Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a

Published 2017 View Full Article

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Title
Structural Basis for Guide RNA Processing and Seed-Dependent DNA Targeting by CRISPR-Cas12a
Authors
Keywords
CRISPR-Cas, Cpf1, Cas12a, Cas9, CRISPR RNA, crRNA processing, seed sequence, R-loop, target DNA cleavage, nuclease
Journal
MOLECULAR CELL
Volume 66, Issue 2, Pages 221-233.e4
Publisher
Elsevier BV
Online
2017-04-21
DOI
10.1016/j.molcel.2017.03.016

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