Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK
Authors
Keywords
-
Journal
NEUROTOXICITY RESEARCH
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-05-06
DOI
10.1007/s12640-019-00047-5
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Endothelial PPARγ (Peroxisome Proliferator–Activated Receptor-γ) Is Essential for Preventing Endothelial Dysfunction With AgingNovelty and Significance
- (2018) T. Michael De Silva et al. HYPERTENSION
- Functional Regulation of PPARs through Post-Translational Modifications
- (2018) Reinhard Brunmeir et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Comparison of cytokine modulation by natural peroxisome proliferator–activated receptor γ ligands with synthetic ligands in intestinal-like Caco-2 cells and human dendritic cells—potential for dietary modulation of peroxisome proliferator–activated receptor γ in intestinal inflammation
- (2018) Rachel Marion-Letellier et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- PPARγ1 as a Molecular Target of Eicosapentaenoic Acid in Human Colon Cancer (HT-29) Cells
- (2018) Clinton D. Allred et al. JOURNAL OF NUTRITION
- The RhoA/ROCK Pathway Ameliorates Adhesion and Inflammatory Infiltration Induced by AGEs in Glomerular Endothelial Cells
- (2017) Jialing Rao et al. Scientific Reports
- Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling
- (2017) Connor A. Emdin et al. CIRCULATION
- Endothelial PPAR-γ provides vascular protection from IL-1β-induced oxidative stress
- (2016) Masashi Mukohda et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Inflammatory Bowel Disease in Asia: A Second Chance at Uncovering Environmental Factors
- (2016) Lindsey Konkel ENVIRONMENTAL HEALTH PERSPECTIVES
- PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease
- (2016) Juan Carlos Corona et al. FREE RADICAL BIOLOGY AND MEDICINE
- Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular FunctionNovelty and Significance
- (2016) T. Michael De Silva et al. HYPERTENSION
- Practical alternatives to chronic caloric restriction for optimizing vascular function with ageing
- (2016) Christopher R. Martens et al. JOURNAL OF PHYSIOLOGY-LONDON
- Interference with PPARγ in endothelium accelerates angiotensin II-induced endothelial dysfunction
- (2016) Chunyan Hu et al. PHYSIOLOGICAL GENOMICS
- Endothelial PPAR-γ Protects Against Vascular Thrombosis by Downregulating P-Selectin ExpressionSignificance
- (2015) Hong Jin et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Prostaglandin D2-loaded microspheres effectively activate macrophage effector functions
- (2015) Priscilla Aparecida Tartari Pereira et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Protective effect of pioglitazone on sepsis-induced intestinal injury in a rodent model
- (2015) Min Gao et al. JOURNAL OF SURGICAL RESEARCH
- PPARγand the Innate Immune System Mediate the Resolution of Inflammation
- (2015) Amanda Croasdell et al. PPAR Research
- Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review
- (2014) Limei Wang et al. BIOCHEMICAL PHARMACOLOGY
- Cyclo-oxygenase-2 inhibition and endothelium-dependent vasodilation in youngervs. older healthy adults
- (2014) John H. Eisenach et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- IL-13 Attenuates Gastrointestinal Candidiasis in Normal and Immunodeficient RAG-2-/- Mice via Peroxisome Proliferator-Activated Receptor- Activation
- (2014) A. Coste et al. JOURNAL OF IMMUNOLOGY
- The Peroxisome Proliferator-Activated Receptor Agonist Rosiglitazone Ameliorates Murine Lupus by Induction of Adiponectin
- (2014) T. Aprahamian et al. JOURNAL OF IMMUNOLOGY
- Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease
- (2014) Augusta Pisanu et al. NEUROBIOLOGY OF DISEASE
- You're Only as Old as Your Arteries: Translational Strategies for Preserving Vascular Endothelial Function with Aging
- (2014) Douglas R. Seals et al. PHYSIOLOGY
- PPAR Gamma agonists regulate tobacco smoke-induced toll like receptor 4 expression in alveolar macrophages
- (2014) Yan Yin et al. RESPIRATORY RESEARCH
- Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase
- (2013) Peter Toth et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Dominant negative PPARγ promotes atherosclerosis, vascular dysfunction, and hypertension through distinct effects in endothelium and vascular muscle
- (2013) Christopher J. Pelham et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Rho/Rho-Associated Coiled-Coil Forming Kinase Pathway as Therapeutic Targets for Statins in Atherosclerosis
- (2013) Naoki Sawada et al. ANTIOXIDANTS & REDOX SIGNALING
- Increased risk of CVD after VT is determined by common etiologic factors
- (2013) R. E. J. Roach et al. BLOOD
- Targeting the “Cytokine Storm” for Therapeutic Benefit
- (2013) Riccardo V. D'Elia et al. Clinical and Vaccine Immunology
- Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes
- (2013) Masato Kajikawa et al. HYPERTENSION
- The Nitrated Fatty Acid 10-Nitro-Oleate Attenuates Allergic Airway Disease
- (2013) A. T. Reddy et al. JOURNAL OF IMMUNOLOGY
- Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells
- (2013) Anke Jaudszus et al. JOURNAL OF LIPID RESEARCH
- Proinflammation: the key to arterial aging
- (2013) Mingyi Wang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Peroxisome proliferator-activated receptor-γ protects against vascular aging
- (2012) Mary L. Modrick et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Pro- and Antiatherogenic Effects of a Dominant-Negative P465L Mutation of Peroxisome Proliferator–Activated Receptor-γ in Apolipoprotein E–Null Mic
- (2012) Avani A. Pendse et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Effects of peroxisome proliferator-activated receptor-γ agonists on the generation of microparticles by monocytes/macrophages
- (2012) Tommaso Neri et al. CARDIOVASCULAR RESEARCH
- Age-related differences in the effects of α and γ peroxisome proliferator-activated receptor subtype agonists on endothelial vasodilation in human microvessels
- (2012) Javier Angulo et al. EXPERIMENTAL GERONTOLOGY
- Emerging PPARγ-Independent Role of PPARγLigands in Lung Diseases
- (2012) Ajit A. Kulkarni et al. PPAR Research
- PPARγin Inflammatory Bowel Disease
- (2012) Vito Annese et al. PPAR Research
- Differential Modulation of Nitric Oxide Synthases in Aging: Therapeutic Opportunities
- (2012) Stefany B. A. Cau et al. Frontiers in Physiology
- Mechanisms Involved in the Aging-Induced Vascular Dysfunction
- (2012) Mariam El Assar et al. Frontiers in Physiology
- Arterial–Ventricular Coupling with Aging and Disease
- (2012) Paul D. Chantler et al. Frontiers in Physiology
- Superoxide-lowering therapy with TEMPOL reverses arterial dysfunction with aging in mice
- (2011) Bradley S. Fleenor et al. AGING CELL
- Protecting against vascular disease in brain
- (2011) Frank M. Faraci AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Aerobic exercise reverses arterial inflammation with aging in mice
- (2011) Lisa A. Lesniewski et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation
- (2011) Tamas Varga et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Linoleic acid enhances angiogenesis through suppression of angiostatin induced by plasminogen activator inhibitor 1
- (2011) N Nishioka et al. BRITISH JOURNAL OF CANCER
- Aging and vascular endothelial function in humans
- (2011) Douglas R. Seals et al. CLINICAL SCIENCE
- Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
- (2011) Jeng-Jiann Chiu et al. PHYSIOLOGICAL REVIEWS
- Optimizing clinical use of mesalazine (5-aminosalicylic acid) in inflammatory bowel disease
- (2011) Chadwick Williams et al. Therapeutic Advances in Gastroenterology
- Cardiovascular Pathology in Hutchinson-Gilford Progeria: Correlation With the Vascular Pathology of Aging
- (2010) Michelle Olive et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Glucagon-Like Peptide 1 Prevents Reactive Oxygen Species–Induced Endothelial Cell Senescence Through the Activation of Protein Kinase A
- (2010) Hisko Oeseburg et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Analyses of association between PPAR gamma and EPHX1 polymorphisms and susceptibility to COPD in a Hungarian cohort, a case-control study
- (2010) Andras Penyige et al. BMC Medical Genetics
- Pioglitazone improves lipid and insulin levels in overweight rats on a high cholesterol and fructose diet by decreasing hepatic inflammation
- (2010) Massimo Collino et al. BRITISH JOURNAL OF PHARMACOLOGY
- Reactive oxygen species and vascular biology: implications in human hypertension
- (2010) Rhian M Touyz et al. HYPERTENSION RESEARCH
- Does Peroxisome Proliferator-activated Receptor-γ (PPARγ) Protect from Hypertension Directly through Effects in the Vasculature?
- (2010) Pimonrat Ketsawatsomkron et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mechanisms of Vascular Aging: New Perspectives
- (2010) Z. Ungvari et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components
- (2010) Harry Martin MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5
- (2010) Jang Hyun Choi et al. NATURE
- PPARγagonist rosiglitazone is neuroprotective after traumatic spinal cord injury via anti-inflammatory in adult rats
- (2010) Qin Zhang et al. NEUROLOGICAL RESEARCH
- Endothelial dysfunction in aged humans is related with oxidative stress and vascular inflammation
- (2009) Leocadio Rodríguez-Mañas et al. AGING CELL
- Role of oxidative stress and AT1 receptors in cerebral vascular dysfunction with aging
- (2009) Mary L. Modrick et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- PPAR Variant Influences Angiographic Outcome and 10-Year Cardiovascular Risk in Male Symptomatic Coronary Artery Disease Patients
- (2009) J. J. Regieli et al. DIABETES CARE
- Oxidative stress and accelerated vascular aging: implications for cigarette smoking
- (2009) Anna Csiszar Frontiers in Bioscience-Landmark
- Endothelial and Vascular Muscle PPARγ in Arterial Pressure Regulation
- (2009) Curt D. Sigmund HYPERTENSION
- Distribution of peroxisome proliferator–activated receptor–gamma polymorphisms in Chinese and Dutch patients with inflammatory bowel disease
- (2009) Umid Kumar Shrestha et al. INFLAMMATORY BOWEL DISEASES
- Inflammatory bowel disease: A survey of the epidemiology in Asia
- (2009) KL GOH et al. Journal of Digestive Diseases
- The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity
- (2009) Luisa Klotz et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The fate of an endothelium layer after preconditioning
- (2009) Saami K. Yazdani et al. JOURNAL OF VASCULAR SURGERY
- Erratum: PPAR-γ agonist attenuates renal interstitial fibrosis and inflammation through reduction of TGF-β
- (2009) Toru Kawai et al. LABORATORY INVESTIGATION
- PPARγ activation in adipocytes is sufficient for systemic insulin sensitization
- (2009) Shigeki Sugii et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Association of peroxisome proliferator-activated receptor-gamma gene polymorphisms with the development of asthma
- (2009) Sun-Hee Oh et al. RESPIRATORY MEDICINE
- Dietary Modulation of Inflammation-Induced Colorectal Cancer through PPARγ
- (2009) Ashlee B. Carter et al. PPAR Research
- Pparγ2 Is a Key Driver of Longevity in the Mouse
- (2009) Carmen Argmann et al. PLoS Genetics
- Aging is associated with greater nuclear NFκB, reduced IκBα, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans
- (2008) Anthony J. Donato et al. AGING CELL
- Sepsis-induced inhibition of neutrophil chemotaxis is mediated by activation of peroxisome proliferator-activated receptor-
- (2008) R. C. Reddy et al. BLOOD
- Rosiglitazone, a PPAR gamma agonist, attenuates inflammation after surgical brain injury in rodents
- (2008) Amy Hyong et al. BRAIN RESEARCH
- Endothelium-Specific Interference With Peroxisome Proliferator Activated Receptor Gamma Causes Cerebral Vascular Dysfunction in Response to a High-Fat Diet
- (2008) Andreas M. Beyer et al. CIRCULATION RESEARCH
- Peroxisome Proliferator-Activated Receptor-γ–Mediated Effects in the Vasculature
- (2008) Sheng Zhong Duan et al. CIRCULATION RESEARCH
- Rosiglitazone for Active Ulcerative Colitis: A Randomized Placebo-Controlled Trial
- (2008) James D. Lewis et al. GASTROENTEROLOGY
- Comparison of Pioglitazone vs Glimepiride on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes
- (2008) Steven E. Nissen et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARγ−/−, PPARδ−/−, PPARγδ−/−, or LXRαβ−/−bone marrow
- (2008) Chaitra Marathe et al. JOURNAL OF LIPID RESEARCH
- Structural Insight into PPARγ Activation Through Covalent Modification with Endogenous Fatty Acids
- (2008) Tsuyoshi Waku et al. JOURNAL OF MOLECULAR BIOLOGY
- Duration of feeding linseed diet influences peroxisome proliferator-activated receptor γ and tumor necrosis factor gene expression, and muscle mass of growing–finishing barrows
- (2008) F.R. Huang et al. Livestock Science
- Age-Related Alterations in Reactivity of Cerebral Arterioles: Role of Oxidative Stress
- (2008) William G. Mayhan et al. MICROCIRCULATION
- Structural basis for the activation of PPARγ by oxidized fatty acids
- (2008) Toshimasa Itoh et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Association of the PPARγ gene polymorphism Pro12Ala with delayed onset of multiple sclerosis
- (2008) Luisa Klotz et al. NEUROSCIENCE LETTERS
- Amelioration of pulmonary dysfunction and neutrophilic inflammation by PPARγ agonist in LPS-exposed guinea pigs
- (2008) Rohini Sharma et al. PULMONARY PHARMACOLOGY & THERAPEUTICS
- A clinical trial of combined use of rosiglitazone and 5-aminosalicylate for ulcerative colitis
- (2008) Hong-Liang Liang et al. WORLD JOURNAL OF GASTROENTEROLOGY
- SOCS 3 and PPAR-γ ligands inhibit the expression of IL-6 and TGF-β1 by regulating JAK2/STAT3 signaling in pancreas
- (2007) Ji Hoon Yu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation