Dominant negative PPARγ promotes atherosclerosis, vascular dysfunction, and hypertension through distinct effects in endothelium and vascular muscle

Pro- and Antiatherogenic Effects of a Dominant-Negative P465L Mutation of Peroxisome Proliferator–Activated Receptor-γ in Apolipoprotein E–Null Mic

(2012) Avani A. Pendse et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

Cullin-3 Regulates Vascular Smooth Muscle Function and Arterial Blood Pressure via PPARγ and RhoA/Rho-Kinase

(2012) Christopher J. Pelham et al.   Cell Metabolism

Renal proximal tubule angiotensin AT1A receptors regulate blood pressure

(2011) Huiping Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Disruption of Endothelial Peroxisome Proliferator-Activated Receptor γ Accelerates Diet-Induced Atherogenesis in LDL Receptor-Null Mice

(2011) Aijuan Qu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Pioglitazone-Induced Reductions in Atherosclerosis Occur via Smooth Muscle Cell–Specific Interaction With PPARγ

(2010) Venkateswaran Subramanian et al.   CIRCULATION RESEARCH

Vascular smooth muscle cell peroxisome proliferator-activated receptor-γ deletion promotes abdominal aortic aneurysms

(2010) Milton Hamblin et al.   JOURNAL OF VASCULAR SURGERY

Anti-diabetic drugs inhibit obesity-linked phosphorylation of PPARγ by Cdk5

(2010) Jang Hyun Choi et al.   NATURE

MARQ: an online tool to mine GEO for experiments with similar or opposite gene expression signatures

(2010) Miguel Vazquez et al.   NUCLEIC ACIDS RESEARCH

ANG II infusion promotes abdominal aortic aneurysms independent of increased blood pressure in hypercholesterolemic mice

(2009) Lisa A. Cassis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Dominant-Negative Loss of PPARγ Function Enhances Smooth Muscle Cell Proliferation, Migration, and Vascular Remodeling

(2009) Dane Meredith et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Bioinformatic Analysis of Gene Sets Regulated by Ligand-Activated and Dominant-Negative Peroxisome Proliferator–Activated Receptor γ in Mouse Aorta

(2009) Henry L. Keen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Vascular Smooth Muscle Cell–Selective Peroxisome Proliferator–Activated Receptor-γ Deletion Leads to Hypotension

(2009) Lin Chang et al.   CIRCULATION

Rosiglitazone evaluated for cardiovascular outcomes in oral agent combination therapy for type 2 diabetes (RECORD): a multicentre, randomised, open-label trial

(2009) Philip D Home et al.   LANCET

Interference with PPARγ Function in Smooth Muscle Causes Vascular Dysfunction and Hypertension

(2008) Carmen M. Halabi et al.   Cell Metabolism

Endothelium-Specific Interference With Peroxisome Proliferator Activated Receptor Gamma Causes Cerebral Vascular Dysfunction in Response to a High-Fat Diet

(2008) Andreas M. Beyer et al.   CIRCULATION RESEARCH

Interference With PPARγ Signaling Causes Cerebral Vascular Dysfunction, Hypertrophy, and Remodeling

(2008) Andreas M. Beyer et al.   HYPERTENSION

Comparison of Pioglitazone vs Glimepiride on Progression of Coronary Atherosclerosis in Patients With Type 2 Diabetes

(2008) Steven E. Nissen et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE