Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia

Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans

(2017) Tobias Weil et al.   mSphere

The Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Strains Is Attributed to Attenuating Fungal Virulence

(2016) Wenrui Gu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protein aggregation as a mechanism of adaptive cellular responses

(2016) Juha Saarikangas et al.   CURRENT GENETICS

Targeting efflux pumps to overcome antifungal drug resistance

(2016) Ann R Holmes et al.   Future Medicinal Chemistry

Scope and frequency of fluconazole trailing assessed using EUCAST in invasiveCandidaspp. isolates

(2016) Laura Judith Marcos-Zambrano et al.   MEDICAL MYCOLOGY

diskImageR: quantification of resistance and tolerance to antimicrobial drugs using disk diffusion assays

(2016) Aleeza C. Gerstein et al.   MICROBIOLOGY-SGM

Distinguishing between resistance, tolerance and persistence to antibiotic treatment

(2016) Asher Brauner et al.   NATURE REVIEWS MICROBIOLOGY

Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans

(2016) Shuyuan Liu et al.   PLoS One

Heteroresistance to Fluconazole Is a Continuously Distributed Phenotype among Candida glabrata Clinical Strains Associated with In Vivo Persistence

(2016) Ronen Ben-Ami et al.   mBio

Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach

(2016) Praveen R. Juvvadi et al.   Virulence

In Vitro Susceptibility and Trailing Growth Effect of Clinical Isolates of Candida Species to Azole Drugs

(2016) Kamiar Zomorodian et al.   Jundishapur Journal of Microbiology

Trafficking through the Late Endosome Significantly Impacts Candida albicans Tolerance of the Azole Antifungals

(2015) Arturo Luna-Tapia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Defining the frontiers between antifungal resistance, tolerance and the concept of persistence

(2015) Eric Delarze et al.   DRUG RESISTANCE UPDATES

A LAPF/phafin1-like protein regulates TORC1 and lysosomal membrane permeabilization in response to endoplasmic reticulum membrane stress

(2015) Adam Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Disruption of the Transcriptional Regulator Cas5 Results in Enhanced Killing of Candida albicans by Fluconazole

(2014) Erin M. Vasicek et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

UPC2 Is Universally Essential for Azole Antifungal Resistance in Candida albicans

(2014) Erin M. Vasicek et al.   EUKARYOTIC CELL

Genetic and phenotypic intra-species variation inCandida albicans

(2014) Matthew P. Hirakawa et al.   GENOME RESEARCH

Prognostic factors and historical trends in the epidemiology of candidemia in critically ill patients: an analysis of five multicenter studies sequentially conducted over a 9-year period

(2014) Arnaldo L. Colombo et al.   INTENSIVE CARE MEDICINE

Phenotypic Resistance and the Dynamics of Bacterial Escape from Phage Control

(2014) James J. Bull et al.   PLoS One

Mechanisms of Antifungal Drug Resistance

(2014) Leah E. Cowen et al.   Cold Spring Harbor Perspectives in Medicine

A Tetraploid Intermediate Precedes Aneuploid Formation in Yeasts Exposed to Fluconazole

(2014) Benjamin D. Harrison et al.   PLOS BIOLOGY

Efflux pump proteins in antifungal resistance

(2014) Rajendra Prasad et al.   Frontiers in Pharmacology

ScanLag: High-throughput Quantification of Colony Growth and Lag Time

(2014) Irit Levin-Reisman et al.   Jove-Journal of Visualized Experiments

Using Galleria mellonella–Candida albicans Infection Model to Evaluate Antifungal Agents

(2013) De-Dong Li et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Molecular epidemiology, phylogeny and evolution of Candida albicans

(2013) Brenda A. McManus et al.   INFECTION GENETICS AND EVOLUTION

Kch1 Family Proteins Mediate Essential Responses to Endoplasmic Reticulum Stresses in the YeastsSaccharomyces cerevisiaeandCandida albicans

(2013) Christopher P. Stefan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A problem of persistence: still more questions than answers?

(2013) Nathalie Q. Balaban et al.   NATURE REVIEWS MICROBIOLOGY

Epidemiology of Candidemia in Latin America: A Laboratory-Based Survey

(2013) Marcio Nucci et al.   PLoS One

Potent Synergistic Effect of Doxycycline with Fluconazole against Candida albicans Is Mediated by Interference with Iron Homeostasis

(2012) Alessandro Fiori et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Resistance by Loss of Function of the Sterol Δ5,6-Desaturase Gene (ERG3) in Candida albicans Does Not Necessarily Decrease Virulence

(2012) L. A. Vale-Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Antidepressant Sertraline Provides a Promising Therapeutic Option for Neurotropic Cryptococcal Infections

(2012) Bing Zhai et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of Treatment Strategy on Outcomes in Patients with Candidemia and Other Forms of Invasive Candidiasis: A Patient-Level Quantitative Review of Randomized Trials

(2012) D. R. Andes et al.   CLINICAL INFECTIOUS DISEASES

EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)*

(2012) Maiken C. Arendrup et al.   CLINICAL MICROBIOLOGY AND INFECTION

Persistent candidemia in neonatal care units: risk factors and clinical significance

(2012) Majeda S. Hammoud et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Progress in Antifungal Susceptibility Testing of Candida spp. by Use of Clinical and Laboratory Standards Institute Broth Microdilution Methods, 2010 to 2012

(2012) M. A. Pfaller et al.   JOURNAL OF CLINICAL MICROBIOLOGY

The Hsp90 Co-Chaperone Sgt1 Governs Candida albicans Morphogenesis and Drug Resistance

(2012) Rebecca S. Shapiro et al.   PLoS One

Bet Hedging in Yeast by Heterogeneous, Age-Correlated Expression of a Stress Protectant

(2012) Sasha F. Levy et al.   PLOS BIOLOGY

Mapping the Hsp90 Genetic Interaction Network in Candida albicans Reveals Environmental Contingency and Rewired Circuitry

(2012) Stephanie Diezmann et al.   PLoS Genetics

Regulation of Efflux Pump Expression and Drug Resistance by the Transcription Factors Mrr1, Upc2, and Cap1 in Candida albicans

(2011) Sabrina Schubert et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of Fluconazole on the Secretome, the Wall Proteome, and Wall Integrity of the Clinical Fungus Candida albicans

(2011) Alice G. Sorgo et al.   EUKARYOTIC CELL

The Clinical Predictive Value (or Lack Thereof) of the Results of In Vitro Antimicrobial Susceptibility Tests

(2011) G. V. Doern et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Calcineurin Signaling and Membrane Lipid Homeostasis Regulates Iron Mediated MultiDrug Resistance Mechanisms in Candida albicans

(2011) Saif Hameed et al.   PLoS One

Direct effects of non-antifungal agents used in cancer chemotherapy and organ transplantation on the development and virulence ofCandidaandAspergillusspecies

(2011) Sharon C-A. Chen et al.   Virulence

Trailing end-point phenotype antibiotic-sensitive strains of Candida albicans produce different amounts of aspartyl peptidases

(2010) L.A. Braga-Silva et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Multilocus sequence typing of sequentialCandida albicansisolates from patients with persistent or recurrent fungemia

(2010) Daniel A. Da Matta et al.   MEDICAL MYCOLOGY

PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90

(2010) Shantelle L. LaFayette et al.   PLoS Pathogens

Property Differences among the Four MajorCandida albicansStrain Clades

(2009) Donna M. MacCallum et al.   EUKARYOTIC CELL

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence

(2009) Jennifer L. Reedy et al.   FUNGAL GENETICS AND BIOLOGY

Stress-Induced Phenotypic Switching in Candida albicans

(2009) Kevin Alby et al.   MOLECULAR BIOLOGY OF THE CELL

Harnessing Hsp90 function as a powerful, broadly effective therapeutic strategy for fungal infectious disease

(2009) Leah E. Cowen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synergistic Effect of Calcineurin Inhibitors and Fluconazole against Candida albicans Biofilms

(2008) P. Uppuluri et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Factors influencing the trailing endpoint observed in Candida albicans susceptibility testing using the CLSI procedure

(2008) T. Coenye et al.   CLINICAL MICROBIOLOGY AND INFECTION