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Title
mRNA-to-protein translation in hypoxia
Authors
Keywords
Hypoxia, mRNA-to-protein translation, HIF, Hypoxia-inducible factor, Cancer, HIF inhibitors
Journal
Molecular Cancer
Volume 18, Issue 1, Pages -
Publisher
Springer Nature
Online
2019-03-30
DOI
10.1186/s12943-019-0968-4
References
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Note: Only part of the references are listed.- GSNO promotes functional recovery in experimental TBI by stabilizing HIF-1α
- (2018) Mushfiquddin Khan et al. BEHAVIOURAL BRAIN RESEARCH
- Defining the role of the tumor vasculature in antitumor immunity and immunotherapy
- (2018) Marco B. Schaaf et al. Cell Death & Disease
- TThe role of hypoxia-inducible factors in leukemias
- (2018) Donata Szymczak et al. Advances in Clinical and Experimental Medicine
- Role of hypoxia in Diffuse Large B-cell Lymphoma: Metabolic repression and selective translation of HK2 facilitates development of DLBCL
- (2018) Kavita Bhalla et al. Scientific Reports
- A Phase I/II Study of Evofosfamide, A Hypoxia-activated Prodrug with or without Bortezomib in Subjects with Relapsed/Refractory Multiple Myeloma
- (2018) Jacob P. Laubach et al. CLINICAL CANCER RESEARCH
- Spatial Organization of Single mRNPs at Different Stages of the Gene Expression Pathway
- (2018) Srivathsan Adivarahan et al. MOLECULAR CELL
- LincRNA-p21 knockdown enhances radiosensitivity of hypoxic tumor cells by reducing autophagy through HIF-1/Akt/mTOR/P70S6K pathway
- (2017) Yueming Shen et al. EXPERIMENTAL CELL RESEARCH
- Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia
- (2017) Jolieke G. van Oosterwijk et al. JOURNAL OF CLINICAL INVESTIGATION
- Results from a phase I, dose-escalation study of PX-478, an orally available inhibitor of HIF-1α.
- (2017) R. Tibes et al. JOURNAL OF CLINICAL ONCOLOGY
- Roxadustat (FG-4592) Versus Epoetin Alfa for Anemia in Patients Receiving Maintenance Hemodialysis: A Phase 2, Randomized, 6- to 19-Week, Open-Label, Active-Comparator, Dose-Ranging, Safety and Exploratory Efficacy Study
- (2016) Robert Provenzano et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Efficacy of the nanoparticle–drug conjugate CRLX101 in combination with bevacizumab in metastatic renal cell carcinoma: results of an investigator-initiated phase I–IIa clinical trial
- (2016) S. M. Keefe et al. ANNALS OF ONCOLOGY
- Preclinical Efficacy of Bevacizumab with CRLX101, an Investigational Nanoparticle-Drug Conjugate, in Treatment of Metastatic Triple-Negative Breast Cancer
- (2016) E. Pham et al. CANCER RESEARCH
- A Small-Molecule Antagonist of HIF2α Is Efficacious in Preclinical Models of Renal Cell Carcinoma
- (2016) Eli M. Wallace et al. CANCER RESEARCH
- Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent chronic kidney disease
- (2016) Pablo E. Pergola et al. KIDNEY INTERNATIONAL
- On-target efficacy of a HIF-2α antagonist in preclinical kidney cancer models
- (2016) Hyejin Cho et al. NATURE
- Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
- (2016) Caroline Wigerup et al. PHARMACOLOGY & THERAPEUTICS
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Aryl hydrocarbon receptor nuclear translocator (ARNT) isoforms control lymphoid cancer cell proliferation through differentially regulating tumor suppressor p53 activity
- (2016) Kacie A. Gardella et al. Oncotarget
- Systemic Reprogramming of Translation Efficiencies on Oxygen Stimulus
- (2016) J.J. David Ho et al. Cell Reports
- The Cost of Protein Production
- (2016) Moshe Kafri et al. Cell Reports
- Reengineering the Tumor Microenvironment to Alleviate Hypoxia and Overcome Cancer Heterogeneity
- (2016) John D. Martin et al. Cold Spring Harbor Perspectives in Medicine
- The importin α/β-specific inhibitor Ivermectin affects HIF-dependent hypoxia response pathways
- (2015) Friederike K. Kosyna et al. BIOLOGICAL CHEMISTRY
- Factor inhibiting HIF1α (FIH-1) functions as a tumor suppressor in human colorectal cancer by repressing HIF1α pathway
- (2015) Tao Chen et al. CANCER BIOLOGY & THERAPY
- The hypoxia-inducible miR-429 regulates hypoxia-inducible factor-1α expression in human endothelial cells through a negative feedback loop
- (2015) Sylwia Bartoszewska et al. FASEB JOURNAL
- Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis
- (2015) F. Wein et al. HAEMATOLOGICA
- HIF-1α Upregulation due to Depletion of the Free Ubiquitin Pool
- (2015) Jiyoung Kim et al. JOURNAL OF KOREAN MEDICAL SCIENCE
- Elongation Factor 2 Kinase Is Regulated by Proline Hydroxylation and Protects Cells during Hypoxia
- (2015) Claire E. J. Moore et al. MOLECULAR AND CELLULAR BIOLOGY
- The PI3K/Akt Pathway Regulates Oxygen Metabolism via Pyruvate Dehydrogenase (PDH)-E1 Phosphorylation
- (2015) G. J. Cerniglia et al. MOLECULAR CANCER THERAPEUTICS
- Progress on hypoxia-inducible factor-3: Its structure, gene regulation and biological function (Review)
- (2015) SHENG-LI YANG et al. Molecular Medicine Reports
- Diversity and selectivity in mRNA translation on the endoplasmic reticulum
- (2015) David W. Reid et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
- (2015) Jonas J. Staudacher et al. NUCLEIC ACIDS RESEARCH
- Probing the closed-loop model of mRNA translation in living cells
- (2015) Stuart K Archer et al. RNA Biology
- Immune Response Regulation in the Tumor Microenvironment by Hypoxia
- (2015) Sara Labiano et al. SEMINARS IN ONCOLOGY
- Defective Beclin-1 and elevated hypoxia-inducible factor (HIF)-1α expression are closely linked to tumorigenesis, differentiation, and progression of hepatocellular carcinoma
- (2015) Nisreen A. A. Osman et al. TUMOR BIOLOGY
- Long noncoding RNA HOTAIR, a hypoxia-inducible factor-1α activated driver of malignancy, enhances hypoxic cancer cell proliferation, migration, and invasion in non-small cell lung cancer
- (2015) Chunxia Zhou et al. TUMOR BIOLOGY
- Positive mRNA Translational Control in Germ Cells by Initiation Factor Selectivity
- (2015) Andrew J. Friday et al. Biomed Research International
- Oxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutes
- (2015) Dmitry E Andreev et al. GENOME BIOLOGY
- Potential role of hypoxia in early stages of Hodgkin lymphoma pathogenesis
- (2015) F. Wein et al. HAEMATOLOGICA
- Hypoxia-Induced Energy Stress Inhibits the mTOR Pathway by Activating an AMPK/REDD1 Signaling Axis in Head and Neck Squamous Cell Carcinoma
- (2015) Abraham Schneider et al. NEOPLASIA
- Reduction of ARNT in myeloid cells causes immune suppression and delayed wound healing
- (2014) Christopher Scott et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Exposure of mice to chronic hypoxia attenuates pulmonary arterial contractile responses to acute hypoxia by increases in extracellular hydrogen peroxide
- (2014) Dhara Patel et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Role of AMP-Activated Protein Kinase in Cancer Therapy
- (2014) Gauhar Rehman et al. ARCHIV DER PHARMAZIE
- Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition
- (2014) Gaofeng Xiong et al. BMC CANCER
- Notch Signaling Drives Stemness and Tumorigenicity of Esophageal Adenocarcinoma
- (2014) Z. Wang et al. CANCER RESEARCH
- Cancer Cells Exploit eIF4E2-Directed Synthesis of Hypoxia Response Proteins to Drive Tumor Progression
- (2014) J. Uniacke et al. CANCER RESEARCH
- Hypoxia-Induced SUMOylation of E3 Ligase HAF Determines Specific Activation of HIF2 in Clear-Cell Renal Cell Carcinoma
- (2014) M. Y. Koh et al. CANCER RESEARCH
- Eukaryotic elongation factor 2 kinase confers tolerance to stress conditions in cancer cells
- (2014) Hongcheng Zhu et al. CELL STRESS & CHAPERONES
- Translational Impact of Nanoparticle-Drug Conjugate CRLX101 with or without Bevacizumab in Advanced Ovarian Cancer
- (2014) E. Pham et al. CLINICAL CANCER RESEARCH
- HIF-1 Signaling in Drug Resistance to Chemotherapy
- (2014) N.A. Warfel et al. CURRENT MEDICINAL CHEMISTRY
- Optimal Translational Termination Requires C4 Lysyl Hydroxylation of eRF1
- (2014) Tianshu Feng et al. MOLECULAR CELL
- Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210
- (2014) Haopeng Wang et al. NATURE IMMUNOLOGY
- An Increase in Reactive Oxygen Species by Deregulation of ARNT Enhances Chemotherapeutic Drug-Induced Cancer Cell Death
- (2014) Jiunn-Min Shieh et al. PLoS One
- Cyclin-dependent kinases regulate lysosomal degradation of hypoxia-inducible factor 1 to promote cell-cycle progression
- (2014) M. E. Hubbi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Translation of the human erythropoietin transcript is regulated by an upstream open reading frame in response to hypoxia
- (2014) C. Barbosa et al. RNA
- Prolyl-4-hydroxylase 2 enhances hypoxia-induced glioblastoma cell death by regulating the gene expression of hypoxia-inducible factor-α
- (2014) W Sun et al. Cell Death & Disease
- Hypoxia-Inducible Factor 3 Is an Oxygen-Dependent Transcription Activator and Regulates a Distinct Transcriptional Response to Hypoxia
- (2014) Peng Zhang et al. Cell Reports
- Ribosomal Readthrough at a Short UGA Stop Codon Context Triggers Dual Localization of Metabolic Enzymes in Fungi and Animals
- (2014) Alina C. Stiebler et al. PLoS Genetics
- Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells
- (2013) Carole de Meester et al. CARDIOVASCULAR RESEARCH
- CDK1 stabilizes HIF-1α via direct phosphorylation of Ser668 to promote tumor growth
- (2013) Noel A Warfel et al. CELL CYCLE
- Transcriptional regulation by hypoxia inducible factors
- (2013) Veronica L. Dengler et al. CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY
- A perspective on mammalian upstream open reading frame function
- (2013) Joanna Somers et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Reciprocal Regulation of HIF-1α and LincRNA-p21 Modulates the Warburg Effect
- (2013) Fan Yang et al. MOLECULAR CELL
- VEGF-A mRNA processing, stability and translation: a paradigm for intricate regulation of gene expression at the post-transcriptional level
- (2013) T. Arcondeguy et al. NUCLEIC ACIDS RESEARCH
- Zinc Finger Nuclease–Mediated Knockout of AHR or ARNT in Human Breast Cancer Cells Abolishes Basal and Ligand-Dependent Regulation of CYP1B1 and Differentially Affects Estrogen Receptor α Transactivation
- (2013) Shaimaa Ahmed et al. TOXICOLOGICAL SCIENCES
- The mTOR Signalling Pathway in Human Cancer
- (2012) Helena Pópulo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Prolyl Hydroxylase-dependent Modulation of Eukaryotic Elongation Factor 2 Activity and Protein Translation under Acute Hypoxia
- (2012) Antonio Romero-Ruiz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An oxygen-regulated switch in the protein synthesis machinery
- (2012) James Uniacke et al. NATURE
- The Elongation, Termination, and Recycling Phases of Translation in Eukaryotes
- (2012) T. E. Dever et al. Cold Spring Harbor Perspectives in Biology
- Poly(A) binding proteins: are they all created equal?
- (2012) Dixie J. Goss et al. Wiley Interdisciplinary Reviews-RNA
- The Hypoxia-Associated Factor Switches Cells from HIF-1 - to HIF-2 -Dependent Signaling Promoting Stem Cell Characteristics, Aggressive Tumor Growth and Invasion
- (2011) M. Y. Koh et al. CANCER RESEARCH
- Cellular IRES-mediated translation
- (2011) Anton A Komar et al. CELL CYCLE
- Multihistology, Target-Driven Pilot Trial of Oral Topotecan as an Inhibitor of Hypoxia-Inducible Factor-1 in Advanced Solid Tumors
- (2011) S. Kummar et al. CLINICAL CANCER RESEARCH
- Primary Role for Endoplasmic Reticulum-bound Ribosomes in Cellular Translation Identified by Ribosome Profiling
- (2011) David W. Reid et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential Sensitivity of Hypoxia Inducible Factor Hydroxylation Sites to Hypoxia and Hydroxylase Inhibitors
- (2011) Ya-Min Tian et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia
- (2011) Aude Carreau et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Molecular Mechanism of Scanning and Start Codon Selection in Eukaryotes
- (2011) A. G. Hinnebusch MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Subcellular FIH-1 expression patterns in invasive breast cancer in relation to HIF-1α expression
- (2011) Agon Hyseni et al. CELLULAR ONCOLOGY
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
- (2010) Ming Yang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- An Upstream Open Reading Frame Regulates Translation of GADD34 during Cellular Stresses That Induce eIF2α Phosphorylation
- (2009) Yun-Young Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans
- (2009) S. E. Calvo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PX-478, an inhibitor of hypoxia-inducible factor-1α, enhances radiosensitivity of prostate carcinoma cells
- (2008) Sanjeewani T. Palayoor et al. INTERNATIONAL JOURNAL OF CANCER
- Should I Stay or Should I Go? Eukaryotic Translation Initiation Factors 1 and 1A Control Start Codon Recognition
- (2008) Sarah F. Mitchell et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-mediated Selective mRNA Translation by an Internal Ribosome Entry Site-independent Mechanism
- (2008) Regina M. Young et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Potent and Highly Selective Hypoxia-Activated Achiral Phosphoramidate Mustards as Anticancer Drugs
- (2008) Jian-Xin Duan et al. JOURNAL OF MEDICINAL CHEMISTRY
- Molecular mechanisms for the activity of PX-478, an antitumor inhibitor of the hypoxia-inducible factor-1
- (2008) M. Y. Koh et al. MOLECULAR CANCER THERAPEUTICS
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