Defective Beclin-1 and elevated hypoxia-inducible factor (HIF)-1α expression are closely linked to tumorigenesis, differentiation, and progression of hepatocellular carcinoma

Hypoxia inducible factors in liver disease and hepatocellular carcinoma: Current understanding and future directions

(2014) Garrick K. Wilson et al.   JOURNAL OF HEPATOLOGY

Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials

(2014) Bruna Scaggiante   WORLD JOURNAL OF GASTROENTEROLOGY

Low expression of Beclin 1 and elevated expression of HIF-1α refine distant metastasis risk and predict poor prognosis of ER-positive, HER2-negative breast cancer

(2013) Min Dong et al.   MEDICAL ONCOLOGY

The impact of hypoxia in hepatocellular carcinoma metastasis

(2013) Carmen Chak-Lui Wong et al.   Frontiers of Medicine

Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma

(2012) Hashem B. El-Serag   GASTROENTEROLOGY

Hepatitis C Virus Upregulates Beclin1 for Induction of Autophagy and Activates mTOR Signaling

(2012) Shubham Shrivastava et al.   JOURNAL OF VIROLOGY

Beclin 1 activation enhances chemosensitivity and predicts a favorable outcome for primary duodenal adenocarcinoma

(2012) Xiang-Yuan Wu et al.   TUMOR BIOLOGY

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis

(2011) Seon-Jin Lee et al.   Autophagy

Gene Expression Profiling of Fixed Tissues Identified Hypoxia-Inducible Factor-1α, VEGF, and Matrix Metalloproteinase-2 as Biomarkers of Lymph Node Metastasis in Hepatocellular Carcinoma

(2011) Zuo-Lin Xiang et al.   CLINICAL CANCER RESEARCH

Hepatocyte-specific hypoxia-inducible factor-1α is a determinant of lipid accumulation and liver injury in alcohol-induced steatosis in mice

(2011) Bharath Nath et al.   HEPATOLOGY

Hypoxia-inducible transcription factor 2α promotes steatohepatitis through augmenting lipid accumulation, inflammation, and fibrosis

(2011) Aijuan Qu et al.   HEPATOLOGY

Decreased Beclin-1 expression is correlated with the growth of the primary tumor in patients with squamous cell carcinoma and adenocarcinoma of the lung

(2011) Kyu Yeoun Won et al.   HUMAN PATHOLOGY

A dual role for hypoxia inducible factor-1α in the hepatitis C virus lifecycle and hepatoma migration

(2011) Garrick K. Wilson et al.   JOURNAL OF HEPATOLOGY

The expression of HIF-1α in primary hepatocellular carcinoma and its correlation with radiotherapy response and clinical outcome

(2011) Zuo-Lin Xiang et al.   MOLECULAR BIOLOGY REPORTS

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

The significance of expression of autophagy-related gene Beclin, Bcl-2, and Bax in breast cancer tissues

(2011) Qing Yao et al.   TUMOR BIOLOGY

Interaction of the human cytomegalovirus particle with the host cell induces hypoxia-inducible factor 1 alpha

(2011) Steven McFarlane et al.   VIROLOGY

Elevated Beclin 1 expression is correlated with HIF-1α in predicting poor prognosis of nasopharyngeal carcinoma

(2010) Xiang-Bo Wan et al.   Autophagy

Regulation of Beclin 1 in autophagy

(2009) Qiming Sun et al.   Autophagy

Hypoxia-inducible factor-1 alpha, in association with inflammation, angiogenesis and MYC, is a critical prognostic factor in patients with HCC after surgery

(2009) Chen-Xin Dai et al.   BMC CANCER

Beclin-1 Expression is a Predictor of Clinical Outcome in Patients with Esophageal Squamous Cell Carcinoma and Correlated to Hypoxia-Inducible Factor (HIF)-1α Expression

(2009) Yongshun Chen et al.   PATHOLOGY & ONCOLOGY RESEARCH

Autophagy: Basic Principles and Relevance to Disease

(2008) Mondira Kundu et al.   Annual Review of Pathology-Mechanisms of Disease

Association of Autophagy Defect with a Malignant Phenotype and Poor Prognosis of Hepatocellular Carcinoma

(2008) Z.-B. Ding et al.   CANCER RESEARCH

Hepatitis B virus X protein sensitizes cells to starvation-induced autophagy via up-regulation of beclin 1 expression

(2008) Hong Tang et al.   HEPATOLOGY

Mitochondrial Autophagy Is an HIF-1-dependent Adaptive Metabolic Response to Hypoxia

(2008) Huafeng Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY