Common motifs in ETAA1 and TOPBP1 required for ATR kinase activation

Quantitative phosphoproteomics reveals mitotic function of the ATR activator ETAA1

(2019) Thomas E. Bass et al.   JOURNAL OF CELL BIOLOGY

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

Targeting the replication stress response in cancer

(2018) Josep V. Forment et al.   PHARMACOLOGY & THERAPEUTICS

An intrinsic S/G2 checkpoint enforced by ATR

(2018) Joshua C. Saldivar et al.   SCIENCE

ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response

(2017) Andrew N. Blackford et al.   MOLECULAR CELL

The essential kinase ATR: ensuring faithful duplication of a challenging genome

(2017) Joshua C. Saldivar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RPA-Binding Protein ETAA1 Is an ATR Activator Involved in DNA Replication Stress Response

(2016) Yuan-Cho Lee et al.   CURRENT BIOLOGY

ETAA1 acts at stalled replication forks to maintain genome integrity

(2016) Thomas E. Bass et al.   NATURE CELL BIOLOGY

Activation of the ATR kinase by the RPA-binding protein ETAA1

(2016) Peter Haahr et al.   NATURE CELL BIOLOGY

RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling

(2015) Laura A Lindsey-Boltz et al.   CELL CYCLE

Probing the Mec1ATRCheckpoint Activation Mechanism with Small Peptides

(2015) Paulina H. Wanrooij et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery

(2013) S. Kumar et al.   GENES & DEVELOPMENT

NBS1 directly activates ATR independently of MRE11 and TOPBP1

(2013) Masahiko Kobayashi et al.   GENES TO CELLS

A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment

(2013) Anja M. Duursma et al.   MOLECULAR CELL

Causes and consequences of replication stress

(2013) Michelle K. Zeman et al.   NATURE CELL BIOLOGY

The Unstructured C-terminal Tail of Yeast Dpb11 (Human TopBP1) Protein Is Dispensable for DNA Replication and the S Phase Checkpoint but Required for the G2/M Checkpoint

(2011) Vasundhara M. Navadgi-Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

(2011) C. Cotta-Ramusino et al.   SCIENCE

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Structure and function of the Rad9-binding region of the DNA-damage checkpoint adaptor TopBP1

(2010) Mathieu Rappas et al.   NUCLEIC ACIDS RESEARCH

The Unstructured C-Terminal Tail of the 9-1-1 Clamp Subunit Ddc1 Activates Mec1/ATR via Two Distinct Mechanisms

(2009) Vasundhara M. Navadgi-Patil et al.   MOLECULAR CELL

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

(2008) D. A. Mordes et al.   GENES & DEVELOPMENT

Yeast DNA Replication Protein Dpb11 Activates the Mec1/ATR Checkpoint Kinase

(2008) Vasundhara M. Navadgi-Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dpb11 activates the Mec1-Ddc2 complex

(2008) D. A. Mordes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA