RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling

Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Definedin VitroSystem

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Direct Role for the Replication Protein Treslin (Ticrr) in the ATR Kinase-mediated Checkpoint Response

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A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment

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Regulation of PCNA–protein interactions for genome stability

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An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence

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In VitroAnalysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling

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Repair complexes of FEN1 endonuclease, DNA, and Rad9-Hus1-Rad1 are distinguished from their PCNA counterparts by functionally important stability

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Characterization of functional domains in human Claspin

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Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)

(2011) Laura A. Lindsey-Boltz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MDC1 collaborates with TopBP1 in DNA replication checkpoint control

(2011) Jiadong Wang et al.   JOURNAL OF CELL BIOLOGY

Contributions of Rad9 to tumorigenesis

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A DNA Damage Response Screen Identifies RHINO, a 9-1-1 and TopBP1 Interacting Protein Required for ATR Signaling

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Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

(2010) Michael G. Kemp et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstitution of RPA-covered single-stranded DNA-activated ATR-Chk1 signaling

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DNA Distress: Just Ring 9-1-1

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The DNA binding domain of human DNA ligase I interacts with both nicked DNA and the DNA sliding clamps, PCNA and hRad9-hRad1-hHus1

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Reconstitution of Human Claspin-mediated Phosphorylation of Chk1 by the ATR (Ataxia Telangiectasia-mutated and Rad3-related) Checkpoint Kinase

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Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex

(2009) Min Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Human Rad9–Hus1–Rad1 Clamp

(2009) Sun Young Sohn et al.   JOURNAL OF MOLECULAR BIOLOGY

The Mre11-Rad50-Nbs1 Complex Mediates Activation of TopBP1 by ATM

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The Unstructured C-Terminal Tail of the 9-1-1 Clamp Subunit Ddc1 Activates Mec1/ATR via Two Distinct Mechanisms

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Crystal Structure of the Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex—Implications for Clamp Loading and Regulation

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ATR: an essential regulator of genome integrity

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Activation of the Cellular DNA Damage Response in the Absence of DNA Lesions

(2008) E. Soutoglou et al.   SCIENCE