Probing the Mec1ATRCheckpoint Activation Mechanism with Small Peptides

Yet another job for Dna2: Checkpoint activation

(2015) Paulina H. Wanrooij et al.   DNA REPAIR

Phosphoproteomics Reveals Distinct Modes of Mec1/ATR Signaling during DNA Replication

(2015) Francisco Meirelles Bastos de Oliveira et al.   MOLECULAR CELL

Lagging strand maturation factor Dna2 is a component of the replication checkpoint initiation machinery

(2013) S. Kumar et al.   GENES & DEVELOPMENT

An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular Senescence

(2013) Zhong-Wei Zhou et al.   PLoS Genetics

Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

(2011) Boris Pfander et al.   EMBO JOURNAL

The Unstructured C-terminal Tail of Yeast Dpb11 (Human TopBP1) Protein Is Dispensable for DNA Replication and the S Phase Checkpoint but Required for the G2/M Checkpoint

(2011) Vasundhara M. Navadgi-Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure and Functional Implications of the Human Rad9-Hus1-Rad1 Cell Cycle Checkpoint Complex

(2009) Min Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of the Human Rad9–Hus1–Rad1 Clamp

(2009) Sun Young Sohn et al.   JOURNAL OF MOLECULAR BIOLOGY

The Unstructured C-Terminal Tail of the 9-1-1 Clamp Subunit Ddc1 Activates Mec1/ATR via Two Distinct Mechanisms

(2009) Vasundhara M. Navadgi-Patil et al.   MOLECULAR CELL

Crystal Structure of the Rad9-Rad1-Hus1 DNA Damage Checkpoint Complex—Implications for Clamp Loading and Regulation

(2009) Andrew S. Doré et al.   MOLECULAR CELL

TopBP1 activates ATR through ATRIP and a PIKK regulatory domain

(2008) D. A. Mordes et al.   GENES & DEVELOPMENT

Yeast DNA Replication Protein Dpb11 Activates the Mec1/ATR Checkpoint Kinase

(2008) Vasundhara M. Navadgi-Patil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dpb11 activates the Mec1-Ddc2 complex

(2008) D. A. Mordes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA