Dysregulation of Circular RNAs in Myotonic Dystrophy Type 1

Circular RNA circHIPK3 Promotes the Proliferation and Differentiation of Chicken Myoblast Cells by Sponging miR-30a-3p

(2019) Biao Chen et al.   Cells

Circular RNA HIPK3 regulates human lens epithelial cells proliferation and apoptosis by targeting the miR-193a/CRYAA axis

(2018) Xin Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cytoplasmic functions of long noncoding RNAs

(2018) Ji Heon Noh et al.   Wiley Interdisciplinary Reviews-RNA

A Zfp609 circular RNA regulates myoblast differentiation by sponging miR-194-5p

(2018) YanHong Wang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Circular RNAs: Methodological challenges and perspectives in cardiovascular diseases

(2018) Matteo Carrara et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Z-band and M-band titin splicing and regulation by RNA binding motif 20 in striated muscles

(2018) Zhilong Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Analysis of extracellular mRNA in human urine reveals splice variant biomarkers of muscular dystrophies

(2018) Layal Antoury et al.   Nature Communications

Transcriptome alterations in myotonic dystrophy skeletal muscle and heart

(2018) Eric T Wang et al.   HUMAN MOLECULAR GENETICS

Circular RNAs in Muscle Function and Disease

(2018) Simona Greco et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Translation of CircRNAs

(2017) Nagarjuna Reddy Pamudurti et al.   MOLECULAR CELL

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

Circular RNAs in cancer: opportunities and challenges in the field

(2017) L S Kristensen et al.   ONCOGENE

Receptor and post-receptor abnormalities contribute to insulin resistance in myotonic dystrophy type 1 and type 2 skeletal muscle

(2017) Laura Valentina Renna et al.   PLoS One

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

(2017) Monika Piwecka et al.   SCIENCE

Myotonic Dystrophies: State of the Art of New Therapeutic Developments for the CNS

(2017) Genevieve Gourdon et al.   Frontiers in Cellular Neuroscience

Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p

(2017) Xuefeng Wei et al.   Cell Death & Disease

Identifying and Characterizing circRNA-Protein Interaction

(2017) William W Du et al.   Theranostics

Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential Diagnostic Biomarkers for Human Cancers

(2017) Zuozhang Yang et al.   Theranostics

Silencing Of Circular RNA-ZNF609 Ameliorates Vascular Endothelial Dysfunction

(2017) Chang Liu et al.   Theranostics

Circular RNAs: Identification, biogenesis and function

(2016) Karoline K. Ebbesen et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Autoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript

(2016) Patryk Konieczny et al.   NUCLEIC ACIDS RESEARCH

Unravelling the myotonic dystrophy type 1 clinical spectrum: A systematic registry-based study with implications for disease classification

(2016) M. De Antonio et al.   REVUE NEUROLOGIQUE

Circular RNA profiling reveals an abundant circHIPK3 that regulates cell growth by sponging multiple miRNAs

(2016) Qiupeng Zheng et al.   Nature Communications

Validation of plasma microRNAs as biomarkers for myotonic dystrophy type 1

(2016) A. Perfetti et al.   Scientific Reports

Staufen1 Regulates Multiple Alternative Splicing Events either Positively or Negatively in DM1 Indicating Its Role as a Disease Modifier

(2016) Emma Bondy-Chorney et al.   PLoS Genetics

Dose-Dependent Regulation of Alternative Splicing by MBNL Proteins Reveals Biomarkers for Myotonic Dystrophy

(2016) Stacey D. Wagner et al.   PLoS Genetics

Myotonic dystrophies: An update on clinical aspects, genetic, pathology, and molecular pathomechanisms

(2015) Giovanni Meola et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Circular RNA is enriched and stable in exosomes: a promising biomarker for cancer diagnosis

(2015) Yan Li et al.   CELL RESEARCH

Antagonistic regulation of mRNA expression and splicing by CELF and MBNL proteins

(2015) Eric T. Wang et al.   GENOME RESEARCH

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

RNA mis-splicing in disease

(2015) Marina M. Scotti et al.   NATURE REVIEWS GENETICS

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CIRI: an efficient and unbiased algorithm for de novo circular RNA identification

(2015) Yuan Gao et al.   GENOME BIOLOGY

RNA-binding protein RBM20 represses splicing to orchestrate cardiac pre-mRNA processing

(2014) Henrike Maatz et al.   JOURNAL OF CLINICAL INVESTIGATION

Loss of MBNL Leads to Disruption of Developmentally Regulated Alternative Polyadenylation in RNA-Mediated Disease

(2014) Ranjan Batra et al.   MOLECULAR CELL

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Plasma microRNAs as biomarkers for myotonic dystrophy type 1

(2014) Alessandra Perfetti et al.   NEUROMUSCULAR DISORDERS

MBNL proteins and their target RNAs, interaction and splicing regulation

(2014) Patryk Konieczny et al.   NUCLEIC ACIDS RESEARCH

Splicing biomarkers of disease severity in myotonic dystrophy

(2013) Masayuki Nakamori et al.   ANNALS OF NEUROLOGY

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Identification and Characterization of DM1 Patients by a New Diagnostic Certified Assay: Neuromuscular and Cardiac Assessments

(2013) Rea Valaperta et al.   Biomed Research International

Circular RNAs Are the Predominant Transcript Isoform from Hundreds of Human Genes in Diverse Cell Types

(2012) Julia Salzman et al.   PLoS One

Deregulated MicroRNAs in Myotonic Dystrophy Type 2

(2012) Simona Greco et al.   PLoS One

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats

(2011) François-Xavier Laurent et al.   NUCLEIC ACIDS RESEARCH

Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy

(2010) Hongqing Du et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Health supervision and anticipatory guidance in adult myotonic dystrophy type 1

(2010) C. Gagnon et al.   NEUROMUSCULAR DISORDERS

Dysregulation and cellular mislocalization of specific miRNAs in myotonic dystrophy type 1

(2010) Riccardo Perbellini et al.   NEUROMUSCULAR DISORDERS

MicroRNA signatures in peripheral blood mononuclear cells of chronic heart failure patients

(2010) Christine Voellenkle et al.   PHYSIOLOGICAL GENOMICS

Common micro-RNA signature in skeletal muscle damage and regeneration induced by Duchenne muscular dystrophy and acute ischemia

(2009) Simona Greco et al.   FASEB JOURNAL

Genetic and Chemical Modifiers of a CUG Toxicity Model in Drosophila

(2008) Amparo Garcia-Lopez et al.   PLoS One

A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart

(2008) A. Kalsotra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA