Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Astrocyte Transforming Growth Factor Beta 1 Protects Synapses against Aβ Oligomers in Alzheimer's Disease Model

(2017) Luan Pereira Diniz et al.   JOURNAL OF NEUROSCIENCE

Location and Number of Astrocytes Determine Dopaminergic Neuron Survival and Function Under 6-OHDA Stress Mediated Through Differential BDNF Release

(2017) Indrani Datta et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

(2017) Shannon E Mullican et al.   NATURE MEDICINE

The metabolic effects of GDF15 are mediated by the orphan receptor GFRAL

(2017) Paul J Emmerson et al.   NATURE MEDICINE

Identification of diverse astrocyte populations and their malignant analogs

(2017) Chia-Ching John Lin et al.   NATURE NEUROSCIENCE

Gdf-15 deficiency does not alter vulnerability of nigrostriatal dopaminergic system in MPTP-intoxicated mice

(2016) Venissa Machado et al.   CELL AND TISSUE RESEARCH

Protection of cultured dopamine neurons from MPP+requires a combination of neurotrophic factors

(2016) Juliann D. Jaumotte et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Growth/differentiation factor-15 deficiency compromises dopaminergic neuron survival and microglial response in the 6-hydroxydopamine mouse model of Parkinson's disease

(2016) Venissa Machado et al.   NEUROBIOLOGY OF DISEASE

Aquaporin-4 deficiency diminishes the differential degeneration of midbrain dopaminergic neurons in experimental Parkinson’s disease

(2016) Ji Zhang et al.   NEUROSCIENCE LETTERS

GDF15/MIC1 and MMP9 Cerebrospinal Fluid Levels in Parkinson’s Disease and Lewy Body Dementia

(2016) Walter Maetzler et al.   PLoS One

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Differential Roles of M1 and M2 Microglia in Neurodegenerative Diseases

(2015) Yu Tang et al.   MOLECULAR NEUROBIOLOGY

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

Astrocyte heterogeneity in the brain: from development to disease

(2015) Clarissa Schitine et al.   Frontiers in Cellular Neuroscience

Astrocytic TGF-  Signaling Limits Inflammation and Reduces Neuronal Damage during Central Nervous System Toxoplasma Infection

(2014) E. Cekanaviciute et al.   JOURNAL OF IMMUNOLOGY

Comparison of GDF5 and GDNF as neuroprotective factors for postnatal dopamine neurons in ventral mesencephalic cultures

(2014) Juliann D. Jaumotte et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The hTH-GFP Reporter Rat Model for the Study of Parkinson's Disease

(2014) Lorraine Iacovitti et al.   PLoS One

BMP and TGF-β pathway mediators are critical upstream regulators of Wnt signaling during midbrain dopamine differentiation in human pluripotent stem cells

(2013) Jingli Cai et al.   DEVELOPMENTAL BIOLOGY

Secalonic acid A protects dopaminergic neurons from 1-methyl-4-phenylpyridinium (MPP + )-induced cell death via the mitochondrial apoptotic pathway

(2013) Aifeng Zhai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Astrocytes as a Source for Extracellular Matrix Molecules and Cytokines

(2012) Stefan Wiese et al.   Frontiers in Pharmacology

VTA neurons show a potentially protective transcriptional response to MPTP

(2010) Sudarshan Phani et al.   BRAIN RESEARCH

Gypenosides protects dopaminergic neurons in primary culture against MPP+-induced oxidative injury

(2010) Peng Wang et al.   BRAIN RESEARCH BULLETIN

Astrocyte heterogeneity: an underappreciated topic in neurobiology

(2010) Ye Zhang et al.   CURRENT OPINION IN NEUROBIOLOGY

Functions of astrocytes and their potential as therapeutic targets

(2010) Harold K. Kimelberg et al.   Neurotherapeutics

Fibroblast growth factor 9 prevents MPP+-induced death of dopaminergic neurons and is involved in melatonin neuroprotectionin vivoandin vitro

(2009) Jui-Yen Huang et al.   JOURNAL OF NEUROCHEMISTRY

Neuroscience: Glia — more than just brain glue

(2009) Nicola J. Allen et al.   NATURE

Stereological estimates of dopaminergic, GABAergic and glutamatergic neurons in the ventral tegmental area, substantia nigra and retrorubral field in the rat

(2008) R.G. Nair-Roberts et al.   NEUROSCIENCE

Pedicularioside A from Buddleia lindleyana inhibits cell death induced by 1-methyl-4-phenylpyridinium ions (MPP+) in primary cultures of rat mesencephalic neurons

(2007) Yan-Yun Li et al.   EUROPEAN JOURNAL OF PHARMACOLOGY