GFRAL is the receptor for GDF15 and the ligand promotes weight loss in mice and nonhuman primates

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Mitochondrial energy deficiency leads to hyperproliferation of skeletal muscle mitochondria and enhanced insulin sensitivity

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GDF-15 inhibits integrin activation and mouse neutrophil recruitment through the ALK-5/TGF- RII heterodimer

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Association of Pharmacological Treatments for Obesity With Weight Loss and Adverse Events

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Growth differentiation factor 15 is a myomitokine governing systemic energy homeostasis

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Bone morphogenetic protein-binding endothelial regulator of liver sinusoidal endothelial cells induces iron overload in a fatty liver mouse model

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hNAG-1 increases lifespan by regulating energy metabolism and insulin/IGF-1/mTOR signaling

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Serum Levels of Human MIC-1/GDF15 Vary in a Diurnal Pattern, Do Not Display a Profile Suggestive of a Satiety Factor and Are Related to BMI

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GDF15 regulates Kv2.1-mediated outward K+current through the Akt/mTOR signalling pathway in rat cerebellar granule cells

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Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86

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The Anorectic Actions of the TGFβ Cytokine MIC-1/GDF15 Require an Intact Brainstem Area Postrema and Nucleus of the Solitary Tract

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RET Recognition of GDNF-GFRα1 Ligand by a Composite Binding Site Promotes Membrane-Proximal Self-Association

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Severe malaria is associated with parasite binding to endothelial protein C receptor

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TGF-b Superfamily Cytokine MIC-1/GDF15 Is a Physiological Appetite and Body Weight Regulator

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Growth differentiation factor 15 predicts future insulin resistance and impaired glucose control in obese nondiabetic individuals: results from the XENDOS trial

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Targeting the TGFβ signalling pathway in disease

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Macrophage Inhibitory Cytokine 1 (MIC-1/GDF15) Decreases Food Intake, Body Weight and Improves Glucose Tolerance in Mice on Normal & Obesogenic Diets

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Anorexia/cachexia of chronic diseases: a role for the TGF-β family cytokine MIC-1/GDF15

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Growth differentiation factor 15 deficiency protects against atherosclerosis by attenuating CCR2-mediated macrophage chemotaxis

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Comparison of GFL–GFRα complexes: further evidence relating GFL bend angle to RET signalling

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Caudal Brainstem Processing Is Sufficient for Behavioral, Sympathetic, and Parasympathetic Responses Driven by Peripheral and Hindbrain Glucagon-Like-Peptide-1 Receptor Stimulation

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Identification of Macrophage Inhibitory Cytokine-1 in Adipose Tissue and Its Secretion as an Adipokine by Human Adipocytes

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