Plant breeding at the speed of light: the power of CRISPR/Cas to generate directed genetic diversity at multiple sites

Clonal seeds from hybrid rice by simultaneous genome engineering of meiosis and fertilization genes

(2019) Chun Wang et al.   NATURE BIOTECHNOLOGY

CRISPR Crops: Plant Genome Editing Toward Disease Resistance

(2018) Thorsten Langner et al.   Annual Review of Phytopathology

Towards a more predictable plant breeding pipeline with CRISPR/Cas-induced allelic series to optimize quantitative and qualitative traits

(2018) Armin Scheben et al.   CURRENT OPINION IN PLANT BIOLOGY

Transforming plant biology and breeding with CRISPR/Cas9, Cas12 and Cas13

(2018) Patrick Schindele et al.   FEBS LETTERS

Cutting Edge Genetics: CRISPR/Cas9 Editing of Plant Genomes

(2018) Cara L Soyars et al.   PLANT AND CELL PHYSIOLOGY

CRISPR-guided DNA polymerases enable diversification of all nucleotides in a tunable window

(2018) Shakked O. Halperin et al.   NATURE

Genome editing of upstream open reading frames enables translational control in plants

(2018) Huawei Zhang et al.   NATURE BIOTECHNOLOGY

Multiplex QTL editing of grain-related genes improves yield in elite rice varieties

(2018) Jianping Zhou et al.   PLANT CELL REPORTS

Manipulating mRNA splicing by base editing in plants

(2018) Chenxiao Xue et al.   Science China-Life Sciences

The CRISPR/Cas revolution continues: From efficient gene editing for crop breeding to plant synthetic biology

(2018) Jochen Kumlehn et al.   Journal of Integrative Plant Biology

Efficient C-to-T base editing in plants using a fusion of nCas9 and human APOBEC3A

(2018) Yuan Zong et al.   NATURE BIOTECHNOLOGY

Domestication of wild tomato is accelerated by genome editing

(2018) Tingdong Li et al.   NATURE BIOTECHNOLOGY

De novo domestication of wild tomato using genome editing

(2018) Agustin Zsögön et al.   NATURE BIOTECHNOLOGY

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

(2017) Nicole M. Gaudelli et al.   NATURE

Towards CRISPR/Cas crops - bringing together genomics and genome editing

(2017) Armin Scheben et al.   NEW PHYTOLOGIST

Selective gene dosage by CRISPR-Cas9 genome editing in hexaploid Camelina sativa

(2017) Céline Morineau et al.   PLANT BIOTECHNOLOGY JOURNAL

From classical mutagenesis to nuclease-based breeding - directing natural DNA repair for a natural end-product

(2017) Michael Pacher et al.   PLANT JOURNAL

Rapid generation of genetic diversity by multiplex CRISPR/Cas9 genome editing in rice

(2017) Lan Shen et al.   Science China-Life Sciences

Accelerating the Domestication of New Crops: Feasibility and Approaches

(2017) Jeppe Thulin Østerberg et al.   TRENDS IN PLANT SCIENCE

QTL editing confers opposing yield performance in different rice varieties

(2016) Lan Shen et al.   Journal of Integrative Plant Biology

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

(2016) Alexis C. Komor et al.   NATURE

High-fidelity CRISPR–Cas9 nucleases with no detectable genome-wide off-target effects

(2016) Benjamin P. Kleinstiver et al.   NATURE

Variation in the flowering gene SELF PRUNING 5G promotes day-neutrality and early yield in tomato

(2016) Sebastian Soyk et al.   NATURE GENETICS

Advancing Crop Transformation in the Era of Genome Editing

(2016) Fredy Altpeter et al.   PLANT CELL

Genome engineering and plant breeding: impact on trait discovery and development

(2016) Fabien Nogué et al.   PLANT CELL REPORTS

Kinetics genetics: Incorporating the concept of genomic balance into an understanding of quantitative traits

(2016) James A. Birchler et al.   PLANT SCIENCE

Systematic mapping of functional enhancer–promoter connections with CRISPR interference

(2016) Charles P. Fulco et al.   SCIENCE

Crop Diversity: An Unexploited Treasure Trove for Food Security

(2016) Festo Massawe et al.   TRENDS IN PLANT SCIENCE

Haploids: Constraints and opportunities in plant breeding

(2015) Sangam L. Dwivedi et al.   BIOTECHNOLOGY ADVANCES

Patterns of genomic changes with crop domestication and breeding

(2015) Junpeng Shi et al.   CURRENT OPINION IN PLANT BIOLOGY

Multiplexed, targeted gene editing inNicotiana benthamianafor glyco-engineering and monoclonal antibody production

(2015) Jin Li et al.   PLANT BIOTECHNOLOGY JOURNAL

A multiplex CRISPR/Cas9 platform for fast and efficient editing of multiple genes in Arabidopsis

(2015) Zhengjing Zhang et al.   PLANT CELL REPORTS

Rationally engineered Cas9 nucleases with improved specificity

(2015) I. M. Slaymaker et al.   SCIENCE

Accelerated genome engineering through multiplexing

(2015) Zehua Bao et al.   Wiley Interdisciplinary Reviews-Systems Biology and Medicine

The CRISPR/Cas9 system produces specific and homozygous targeted gene editing in rice in one generation

(2014) Hui Zhang et al.   PLANT BIOTECHNOLOGY JOURNAL

The CRISPR/Cas system can be used as nuclease forin plantagene targeting and as paired nickases for directed mutagenesis in Arabidopsis resulting in heritable progeny

(2014) Simon Schiml et al.   PLANT JOURNAL

Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering inArabidopsis thaliana

(2014) Friedrich Fauser et al.   PLANT JOURNAL

New approaches to facilitate rapid domestication of a wild plant to an oilseed crop: Example pennycress (Thlaspi arvense L.)

(2014) John C. Sedbrook et al.   PLANT SCIENCE

Genomic selection: genome-wide prediction in plant improvement

(2014) Zeratsion Abera Desta et al.   TRENDS IN PLANT SCIENCE

Plant Genome Engineering with Sequence-Specific Nucleases

(2013) Daniel F. Voytas   Annual Review of Plant Biology

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

A Conserved Genetic Pathway Determines Inflorescence Architecture in Arabidopsis and Rice

(2013) Chang Liu et al.   DEVELOPMENTAL CELL

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

(2013) Prashant Mali et al.   NATURE BIOTECHNOLOGY

Multiplex and homologous recombination–mediated genome editing in Arabidopsis and Nicotiana benthamiana using guide RNA and Cas9

(2013) Jian-Feng Li et al.   NATURE BIOTECHNOLOGY

Targeted mutagenesis in the model plant Nicotiana benthamiana using Cas9 RNA-guided endonuclease

(2013) Vladimir Nekrasov et al.   NATURE BIOTECHNOLOGY

Targeted genome modification of crop plants using a CRISPR-Cas system

(2013) Qiwei Shan et al.   NATURE BIOTECHNOLOGY

Evolution of crop species: genetics of domestication and diversification

(2013) Rachel S. Meyer et al.   NATURE REVIEWS GENETICS

Regulation of plant translation by upstream open reading frames

(2013) Albrecht G. von Arnim et al.   PLANT SCIENCE

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence

(2011) Patricia J. Wittkopp et al.   NATURE REVIEWS GENETICS

Evolutionary History of GS3 , a Gene Conferring Grain Length in Rice

(2009) Noriko Takano-Kai et al.   GENETICS

Marker-assisted selection: an approach for precision plant breeding in the twenty-first century

(2007) B. C.Y Collard et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES