Diacylglycerol kinase control of protein kinase C

Protein kinase C: perfectly balanced

(2018) Alexandra C. Newton   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

The invasin D protein fromYersinia pseudotuberculosisselectively binds the Fab region of host antibodies and affects colonization of the intestine

(2018) Pooja Sadana et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential roles of PKC isoforms (PKCs) in GnRH stimulation of MAPK phosphorylation in gonadotrope derived cells

(2018) Shany Mugami et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

PKCα integrates spatiotemporally distinct Ca2+ and autocrine BDNF signaling to facilitate synaptic plasticity

(2018) Lesley A Colgan et al.   NATURE NEUROSCIENCE

The phosphatidic acid paradox: Too many actions for one molecule class? Lessons from plants

(2018) Igor Pokotylo et al.   PROGRESS IN LIPID RESEARCH

A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling

(2018) Jae-Sung You et al.   Science Signaling

A DGKζ-FoxO-ubiquitin proteolytic axis controls fiber size during skeletal muscle remodeling

(2018) Jae-Sung You et al.   Science Signaling

The Physiology of Optimizing Health with a Focus on Exercise as Medicine

(2018) Bente Klarlund Pedersen   Annual Review of Physiology

Predominant contribution of DGKζ over DGKα in the control of PKC/PDK-1-regulated functions in T cells

(2017) Antonia Ávila-Flores et al.   IMMUNOLOGY AND CELL BIOLOGY

Protein kinase C in cancer: The top five unanswered questions

(2017) Mariana Cooke et al.   MOLECULAR CARCINOGENESIS

SNX27 links DGKζ to the control of transcriptional and metabolic programs in T lymphocytes

(2017) M. Tello-Lafoz et al.   Scientific Reports

Diacylglycerol Kinase ζ Limits Cytokine-dependent Expansion of CD8 + T Cells with Broad Antitumor Capacity

(2017) Elena Andrada et al.   EBioMedicine

Signaling and Polarized Communication Across the T Cell Immunological Synapse

(2016) Michael L. Dustin et al.   Annual Review of Cell and Developmental Biology

Diacylglycerol Kinase ζ Is a Target To Enhance NK Cell Function

(2016) Enjun Yang et al.   JOURNAL OF IMMUNOLOGY

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Diacylglycerol kinase   limits the polarized recruitment of diacylglycerol-enriched organelles to the immune synapse in T cells

(2016) E. Andrada et al.   Science Signaling

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer’s disease

(2016) Stephanie I. Alfonso et al.   Science Signaling

FAM21 directs SNX27–retromer cargoes to the plasma membrane by preventing transport to the Golgi apparatus

(2016) Seongju Lee et al.   Nature Communications

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Trisomy 21 consistently activates the interferon response

(2016) Kelly D Sullivan et al.   eLife

Diacylglycerol kinase   limits the polarized recruitment of diacylglycerol-enriched organelles to the immune synapse in T cells

(2016) E. Andrada et al.   Science Signaling

Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer’s disease

(2016) Stephanie I. Alfonso et al.   Science Signaling

Cancer-Associated Protein Kinase C Mutations Reveal Kinase’s Role as Tumor Suppressor

(2015) Corina E. Antal et al.   CELL

Functional and Physical Interaction of Diacylglycerol Kinase   with Protein Kinase C  Is Required for Cerebellar Long-Term Depression

(2015) D. Lee et al.   JOURNAL OF NEUROSCIENCE

Loss of Diacylglycerol Kinase-Ζ Inhibits Cell Proliferation and Survival in Human Gliomas

(2015) Jinfu Diao et al.   MOLECULAR NEUROBIOLOGY

RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines

(2015) O Ksionda et al.   ONCOGENE

Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1

(2015) P Torres-Ayuso et al.   Oncogenesis

Tuning the signalling output of protein kinase C

(2014) Corina E. Antal et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Increased diacylglycerol kinase ζ expression in human metastatic colon cancer cells augments Rho GTPase activity and contributes to enhanced invasion

(2014) Kun Cai et al.   BMC CANCER

Polarised cell migration: intrinsic and extrinsic drivers

(2014) Emma F Woodham et al.   CURRENT OPINION IN CELL BIOLOGY

Synapto-depressive effects of amyloid beta require PICK1

(2014) Stephanie Alfonso et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Lipid dynamics at dendritic spines

(2014) Carlos Gerardo Dotti et al.   Frontiers in Neuroanatomy

Sorting Nexin 27 Regulates Aβ Production through Modulating γ-Secretase Activity

(2014) Xin Wang et al.   Cell Reports

Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells

(2013) Kai Cai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases

(2013) M. J. Riese et al.   CANCER RESEARCH

Interleukin-2 at the Crossroads of Effector Responses, Tolerance, and Immunotherapy

(2013) Wei Liao et al.   IMMUNITY

Transient PKC  shuttling to the immunological synapse is governed by DGK  and regulates L-selectin shedding

(2013) S. I. Gharbi et al.   JOURNAL OF CELL SCIENCE

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Loss of sorting nexin 27 contributes to excitatory synaptic dysfunction by modulating glutamate receptor recycling in Down's syndrome

(2013) Xin Wang et al.   NATURE MEDICINE

Diacylglycerol Kinase   Limits B Cell Antigen Receptor-Dependent Activation of ERK Signaling to Inhibit Early Antibody Responses

(2013) M. L. Wheeler et al.   Science Signaling

The   Isoform of Diacylglycerol Kinase Plays a Predominant Role in Regulatory T Cell Development and TCR-Mediated Ras Signaling

(2013) R. P. Joshi et al.   Science Signaling

Diacylglycerol Kinase   Limits the Generation of Natural Regulatory T Cells

(2013) A. M. Schmidt et al.   Science Signaling

Diacylglycerol kinase α controls RCP-dependent integrin trafficking to promote invasive migration

(2012) Elena Rainero et al.   JOURNAL OF CELL BIOLOGY

Translocation dynamics of sorting nexin 27 in activated T cells

(2011) E. Rincon et al.   JOURNAL OF CELL SCIENCE

Deficiency of Sorting Nexin 27 (SNX27) Leads to Growth Retardation and Elevated Levels of N-Methyl-D-Aspartate Receptor 2C (NR2C)

(2011) L. Cai et al.   MOLECULAR AND CELLULAR BIOLOGY

Diacylglycerol kinase ζ controls diacylglycerol metabolism at the immunological synapse

(2011) Severine I. Gharbi et al.   MOLECULAR BIOLOGY OF THE CELL

A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells

(2011) Emily J Quann et al.   NATURE IMMUNOLOGY

A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28

(2011) Kok-Fai Kong et al.   NATURE IMMUNOLOGY

Diacylglycerol kinase ζ: At the crossroads of lipid signaling and protein complex organization

(2011) Esther Rincón et al.   PROGRESS IN LIPID RESEARCH

Shaping up the membrane: diacylglycerol coordinates spatial orientation of signaling

(2011) María Almena et al.   TRENDS IN BIOCHEMICAL SCIENCES

Identification of a functional nuclear export sequence in diacyl glycerol kinase-ζ

(2010) Camilla Evangelisti et al.   CELL CYCLE

DGKι regulates presynaptic release during mGluR-dependent LTD

(2010) Jinhee Yang et al.   EMBO JOURNAL

Regulation of hippocampal long-term potentiation and long-term depression by diacylglycerol kinaseζ

(2010) Jinsoo Seo et al.   HIPPOCAMPUS

p23/Tmp21 Differentially Targets the Rac-GAP β2-Chimaerin and Protein Kinase C via Their C1 Domains

(2010) HongBin Wang et al.   MOLECULAR BIOLOGY OF THE CELL

Phosphatidic Acid Plays a Regulatory Role in Clathrin-mediated Endocytosis

(2010) Costin N. Antonescu et al.   MOLECULAR BIOLOGY OF THE CELL

Taxonomy and function of C1 protein kinase C homology domains

(2010) James H. Hurley et al.   PROTEIN SCIENCE

Synaptic removal of diacylglycerol by DGKζ and PSD-95 regulates dendritic spine maintenance

(2009) Karam Kim et al.   EMBO JOURNAL

The kinase PDK1 integrates T cell antigen receptor and CD28 coreceptor signaling to induce NF-κB and activate T cells

(2009) Sung-Gyoo Park et al.   NATURE IMMUNOLOGY

Signaling at the membrane interface by the DGK/SK enzyme family

(2008) Daniel M. Raben et al.   JOURNAL OF LIPID RESEARCH

Diacylglycerol kinases: at the hub of cell signalling

(2007) Isabel Mérida et al.   BIOCHEMICAL JOURNAL