Diacylglycerol Kinase ζ Is a Target To Enhance NK Cell Function

SHIP1 Intrinsically Regulates NK Cell Signaling and Education, Resulting in Tolerance of an MHC Class I–Mismatched Bone Marrow Graft in Mice

(2015) Matthew Gumbleton et al.   JOURNAL OF IMMUNOLOGY

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors

(2014) Michele Ardolino et al.   JOURNAL OF CLINICAL INVESTIGATION

Measuring Cytotoxicity by Bioluminescence Imaging Outperforms the Standard Chromium-51 Release Assay

(2014) Mobin A. Karimi et al.   PLoS One

Diacylglycerol kinase   establishes T cell polarity by shaping diacylglycerol accumulation at the immunological synapse

(2014) A. Chauveau et al.   Science Signaling

SHP-1-mediated inhibitory signals promote responsiveness and anti-tumour functions of natural killer cells

(2014) Charlotte Viant et al.   Nature Communications

Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function

(2013) R. M. May et al.   BLOOD

Enhanced Effector Responses in Activated CD8+ T Cells Deficient in Diacylglycerol Kinases

(2013) M. J. Riese et al.   CANCER RESEARCH

NK cell-based immunotherapy for malignant diseases

(2013) Min Cheng et al.   Cellular & Molecular Immunology

The   Isoform of Diacylglycerol Kinase Plays a Predominant Role in Regulatory T Cell Development and TCR-Mediated Ras Signaling

(2013) R. P. Joshi et al.   Science Signaling

Diacylglycerol Kinase   Limits the Generation of Natural Regulatory T Cells

(2013) A. M. Schmidt et al.   Science Signaling

Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses

(2011) Gregory F. Wu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Decreased Diacylglycerol Metabolism Enhances ERK Activation and Augments CD8+T Cell Functional Responses

(2010) Matthew J. Riese et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Poly I:C-Induced Activation of NK Cells by CD8 + Dendritic Cells via the IPS-1 and TRIF-Dependent Pathways

(2009) T. Miyake et al.   JOURNAL OF IMMUNOLOGY

Continuous engagement of a self-specific activation receptor induces NK cell tolerance

(2008) Sandeep K. Tripathy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Up on the tightrope: natural killer cell activation and inhibition

(2008) Lewis L Lanier   NATURE IMMUNOLOGY