RNA interference targeting hypoxia-inducible factor 1α via a novel multifunctional surfactant attenuates glioma growth in an intracranial mouse model

In Vivo c-Met Pathway Inhibition Depletes Human Glioma Xenografts of Tumor-Propagating Stem-Like Cells

(2014) Prakash Rath et al.   Translational Oncology

Molecular analysis of a recurrent glioblastoma treated with bevacizumab

(2013) Takuya Furuta et al.   Brain Tumor Pathology

Glioblastoma Resistance to Anti-VEGF Therapy: Has the Challenge Been MET?

(2013) J. H. McCarty   CLINICAL CANCER RESEARCH

HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations

(2013) Gregg L. Semenza   JOURNAL OF CLINICAL INVESTIGATION

Suppression of Tumor Growth by Designed Dimeric Epidithiodiketopiperazine Targeting Hypoxia-Inducible Transcription Factor Complex

(2013) Ramin Dubey et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Highly Potent and Specific MET Therapeutic Protein Antagonist with Both Ligand-Dependent and Ligand-Independent Activity

(2013) Shane A. Olwill et al.   MOLECULAR CANCER THERAPEUTICS

Targeting Src Family Kinases Inhibits Bevacizumab-Induced Glioma Cell Invasion

(2013) Deborah Huveldt et al.   PLoS One

Arginase II Expressed in Cancer-Associated Fibroblasts Indicates Tissue Hypoxia and Predicts Poor Outcome in Patients with Pancreatic Cancer

(2013) Yoshinori Ino et al.   PLoS One

Pyruvate dehydrogenase kinase as a novel therapeutic target in oncology

(2013) Gopinath Sutendra et al.   Frontiers in Oncology

Lipid-Based Nanoparticles for siRNA Delivery in Cancer Therapy: Paradigms and Challenges

(2012) Lígia C. Gomes-da-Silva et al.   ACCOUNTS OF CHEMICAL RESEARCH

Tissue biomarkers as prognostic variables of cervical cancer

(2012) Angiolo Gadducci et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

A tumor hypoxic niche protects human colon cancer stem cells from chemotherapy

(2012) Qin Mao et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2005-2009

(2012) T. A. Dolecek et al.   NEURO-ONCOLOGY

Mitochondrial activation by inhibition of PDKII suppresses HIF1a signaling and angiogenesis in cancer

(2012) G Sutendra et al.   ONCOGENE

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

A novel approach to cancer therapy using PX-478 as a HIF-1α inhibitor

(2011) Kyeong Lee et al.   ARCHIVES OF PHARMACAL RESEARCH

The Addition of Bevacizumab to Standard Radiation Therapy and Temozolomide Followed by Bevacizumab, Temozolomide, and Irinotecan for Newly Diagnosed Glioblastoma

(2011) J. J. Vredenburgh et al.   CLINICAL CANCER RESEARCH

Glioma Stem Cell Maintenance: The Role of the Microenvironment

(2011) John M. Heddleston et al.   CURRENT PHARMACEUTICAL DESIGN

HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells

(2011) Giuseppina Comito et al.   FREE RADICAL BIOLOGY AND MEDICINE

Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme

(2011) Amparo Wolf et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Outcome after bevacizumab clinical trial therapy among recurrent grade III malignant glioma patients

(2011) David A. Reardon et al.   JOURNAL OF NEURO-ONCOLOGY

Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of  -ketoglutarate to citrate to support cell growth and viability

(2011) D. R. Wise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma

(2011) Olivier Keunen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidative phosphorylation in cancer cells

(2010) Giancarlo Solaini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Glioma proteomics: Status and perspectives

(2010) Simone P. Niclou et al.   Journal of Proteomics

Knock down of HIF-1α in glioma cells reduces migration in vitro and invasion in vivo and impairs their ability to form tumor spheres

(2010) Olga Méndez et al.   Molecular Cancer

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MET molecular mechanisms and therapies in lung cancer

(2010) Ryan E. Lawrence et al.   Cell Adhesion & Migration

Future of convection-enhanced delivery in the treatment of brain tumors

(2009) Dani S Bidros et al.   Future Oncology

Development of HIF-1 inhibitors for cancer therapy

(2009) Barbara Onnis et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target

(2009) Randy L. Jensen   JOURNAL OF NEURO-ONCOLOGY

Targeted Systemic Delivery of a Therapeutic siRNA with a Multifunctional Carrier Controls Tumor Proliferation in Mice

(2009) Xu-Li Wang et al.   MOLECULAR PHARMACEUTICS

Strategies for targeted nonviral delivery of siRNAs in vivo

(2009) Sang-Soo Kim et al.   TRENDS IN MOLECULAR MEDICINE

Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme

(2008) Jeannette R. Flynn et al.   CANCER

Tumor Angiogenic and Hypoxic Profiles Predict Radiographic Response and Survival in Malignant Astrocytoma Patients Treated With Bevacizumab and Irinotecan

(2008) Sith Sathornsumetee et al.   JOURNAL OF CLINICAL ONCOLOGY