Nanoparticle/siRNA-based therapy strategies in glioma: which nanoparticles, which siRNAs?

Hypoxia-responsive ionizable liposome delivery siRNA for glioma therapy

(2017) Hong-Mei Liu et al.   International Journal of Nanomedicine

Liposome-polyethylenimine complexes (DPPC-PEI lipopolyplexes) for therapeutic siRNA delivery in vivo

(2017) Alexander Ewe et al.   Nanomedicine-Nanotechnology Biology and Medicine

Multiplexed RNAi therapy against brain tumor-initiating cells via lipopolymeric nanoparticle infusion delays glioblastoma progression

(2017) Dou Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multifunctional PEI-entrapped gold nanoparticles enable efficient delivery of therapeutic siRNA into glioblastoma cells

(2017) Lingdan Kong et al.   Biomaterials Science

Sensitization of glioblastoma tumor micro-environment to chemo- and immunotherapy by Galectin-1 intranasal knock-down strategy

(2017) Matthias Van Woensel et al.   Scientific Reports

Microparticulate poly(vinyl alcohol) hydrogel formulations for embedding and controlled release of polyethylenimine (PEI)-based nanoparticles

(2016) Jan Schulze et al.   Acta Biomaterialia

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Nanoparticles: Novel vehicles in treatment of Glioblastoma

(2016) Fatemeh Pourgholi et al.   BIOMEDICINE & PHARMACOTHERAPY

Brain tumor-targeted therapy by systemic delivery of siRNA with Transferrin receptor-mediated core-shell nanoparticles

(2016) Lin Wei et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of siRNA-loaded chitosan nanoparticles targeting Galectin-1 for the treatment of glioblastoma multiforme via intranasal administration

(2016) Matthias Van Woensel et al.   JOURNAL OF CONTROLLED RELEASE

Nanocarriers for the treatment of glioblastoma multiforme: Current state-of-the-art

(2016) Reatul Karim et al.   JOURNAL OF CONTROLLED RELEASE

Dual Functional Peptide-Driven Nanoparticles for Highly Efficient Glioma-Targeting and Drug Codelivery

(2016) Yuyang Kuang et al.   MOLECULAR PHARMACEUTICS

Nanoparticles for brain-specific drug and genetic material delivery, imaging and diagnosis

(2016) Inmaculada Posadas et al.   Nanomedicine

Localized RNAi Therapeutics of Chemoresistant Grade IV Glioma Using Hyaluronan-Grafted Lipid-Based Nanoparticles

(2015) Zvi R. Cohen et al.   ACS Nano

Efficient RNA delivery by integrin-targeted glutathione responsive polyethyleneimine capped gold nanorods

(2015) Feihu Wang et al.   Acta Biomaterialia

Targeting glucose uptake with siRNA-based nanomedicine for cancer therapy

(2015) Cong-Fei Xu et al.   BIOMATERIALS

Single-component self-assembled RNAi nanoparticles functionalized with tumor-targeting iNGR delivering abundant siRNA for efficient glioma therapy

(2015) Sai An et al.   BIOMATERIALS

Targeting a Plk1-Controlled Polarity Checkpoint in Therapy-Resistant Glioblastoma-Propagating Cells

(2015) R. G. Lerner et al.   CANCER RESEARCH

Nucleic Acid Therapeutics Using Polyplexes: A Journey of 50 Years (and Beyond)

(2015) Ulrich Lächelt et al.   CHEMICAL REVIEWS

Combined anti-Galectin-1 and anti-EGFR siRNA-loaded chitosan-lipid nanocapsules decrease temozolomide resistance in glioblastoma: In vivo evaluation

(2015) Fabienne Danhier et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma

(2015) Pedro M. Costa et al.   JOURNAL OF CONTROLLED RELEASE

Co-delivery of doxorubicin and siRNA for glioma therapy by a brain targeting system: angiopep-2-modified poly(lactic-co-glycolic acid) nanoparticles

(2015) Lei Wang et al.   JOURNAL OF DRUG TARGETING

Peptide-like Polymers Exerting Effective Glioma-Targeted siRNA Delivery and Release for Therapeutic Application

(2015) Sai An et al.   Small

RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

(2015) Tae Jin Lee et al.   Oncotarget

Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance

(2015) Kimmo J. Hatanpaa et al.   NEOPLASIA

Nanoparticle–Cell Interactions: Molecular Structure of the Protein Corona and Cellular Outcomes

(2014) Candace C. Fleischer et al.   ACCOUNTS OF CHEMICAL RESEARCH

NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age

(2014) G Kenneth Gray et al.   Expert Review of Neurotherapeutics

Combination Treatment with Theranostic Nanoparticles for Glioblastoma Sensitization to TMZ

(2014) Byunghee Yoo et al.   MOLECULAR IMAGING AND BIOLOGY

Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival

(2014) Susann Herzog et al.   NEURO-ONCOLOGY

Assessment of drug delivery and anticancer potentials of nanoparticles-loaded siRNA targeting STAT3 in lung cancer, in vitro and in vivo

(2014) Jayeeta Das et al.   TOXICOLOGY LETTERS

Ultrasound-sensitive siRNA-loaded nanobubbles formed by hetero-assembly of polymeric micelles and liposomes and their therapeutic effect in gliomas

(2013) Tinghui Yin et al.   BIOMATERIALS

T7 peptide-functionalized nanoparticles utilizing RNA interference for glioma dual targeting

(2013) Yuyang Kuang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Relationship between SATB1 expression and prognosis in astrocytoma

(2013) Sheng-Hua Chu et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Inhibition of human glioma U251 cells growth in vitro and in vivo by hydroxyapatite nanoparticle-assisted delivery of short hairpin RNAs against SATB1

(2013) Sheng-Hua Chu et al.   MOLECULAR BIOLOGY REPORTS

STAT3 silencing inhibits glioma single cell infiltration and tumor growth

(2013) M. Priester et al.   NEURO-ONCOLOGY

Spherical Nucleic Acid Nanoparticle Conjugates as an RNAi-Based Therapy for Glioblastoma

(2013) S. A. Jensen et al.   Science Translational Medicine

Phosphorylated SATB1 is associated with the progression and prognosis of glioma

(2013) S Han et al.   Cell Death & Disease

Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle

(2013) Shruti R Saptarshi et al.   JOURNAL OF NANOBIOTECHNOLOGY

Upregulation of SATB1 is associated with the development and progression of glioma

(2012) Sheng-Hua Chu et al.   Journal of Translational Medicine

Correlation between SATB1 and Bcl-2 expression in human glioblastoma multiforme

(2012) SHENG-HUA CHU et al.   Molecular Medicine Reports

In Vivo Specific Delivery of c-Met siRNA to Glioblastoma Using Cationic Solid Lipid Nanoparticles

(2011) Juyoun Jin et al.   BIOCONJUGATE CHEMISTRY

Targeting apoptosis pathways in glioblastoma

(2011) Günter Eisele et al.   CANCER LETTERS

Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

(2011) Lydia Alvarez-Erviti et al.   NATURE BIOTECHNOLOGY

Trabedersen to target transforming growth factor- : when the journey is not the reward, in reference to Bogdahn et al. (Neuro-Oncology 2011;13:132-142)

(2011) W. Wick et al.   NEURO-ONCOLOGY

RNA interference targeting survivin exerts antitumoral effects in vitro and in established glioma xenografts in vivo

(2011) S. Hendruschk et al.   NEURO-ONCOLOGY

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

High loading efficiency and sustained release of siRNA encapsulated in PLGA nanoparticles: Quality by design optimization and characterization

(2010) Dongmei Cun et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers

(2010) Paula Ofek et al.   FASEB JOURNAL

Efficient delivery of liposome-mediated MGMT-siRNA reinforces the cytotoxity of temozolomide in GBM-initiating cells

(2010) T Kato et al.   GENE THERAPY

sAPPα antagonizes dendritic degeneration and neuron death triggered by proteasomal stress

(2010) Ekaterini Copanaki et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Targeted therapy for high-grade glioma with the TGF- 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study

(2010) U. Bogdahn et al.   NEURO-ONCOLOGY

Functional Delivery of siRNA in Mice Using Dendriworms

(2009) Amit Agrawal et al.   ACS Nano

Glioblastoma multiforme: a review of where we have been and where we are going

(2009) Cory Adamson et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Glioblastoma multiforme: a review of therapeutic targets

(2009) Okezie O Kanu et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Therapeutic strategies for inhibiting invasion in glioblastoma

(2009) Jan Drappatz et al.   Expert Review of Neurotherapeutics

Tat-BMPs-PAMAM Conjugates Enhance Therapeutic Effect of Small Interference RNA on U251 Glioma Cells In Vitro and In Vivo

(2009) Lei Han et al.   HUMAN GENE THERAPY

Targeted Systemic Delivery of a Therapeutic siRNA with a Multifunctional Carrier Controls Tumor Proliferation in Mice

(2009) Xu-Li Wang et al.   MOLECULAR PHARMACEUTICS

STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells

(2009) Maureen M. Sherry et al.   STEM CELLS

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

(2008) Roger McLendon et al.   NATURE

An Integrated Genomic Analysis of Human Glioblastoma Multiforme

(2008) D. W. Parsons et al.   SCIENCE