Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions
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Title
Comparison of Effects of Anti-thrombin Aptamers HD1 and HD22 on Aggregation of Human Platelets, Thrombin Generation, Fibrin Formation, and Thrombus Formation Under Flow Conditions
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-02-20
DOI
10.3389/fphar.2019.00068
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- Development of Antithrombotic Aptamers: From Recognizing Elements to Drugs
- (2016) Elena Zavyalova et al. CURRENT PHARMACEUTICAL DESIGN
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- (2013) R. T. McGrath et al. BLOOD
- Ligand Binding to Anion-binding Exosites Regulates Conformational Properties of Thrombin
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- (2013) Sven Danckwardt et al. JOURNAL OF MOLECULAR MEDICINE-JMM
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- (2012) H. Coenraad Hemker et al. THROMBOSIS RESEARCH
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- (2011) G. Mayer et al. Hamostaseologie
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- (2011) Elisabetta Castoldi et al. THROMBOSIS RESEARCH
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- (2011) Erica De Candia THROMBOSIS RESEARCH
- Long Range Communication between Exosites 1 and 2 Modulates Thrombin Function
- (2009) Nicolas S. Petrera et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- HD1, a thrombin- and prothrombin-binding DNA aptamer, inhibits thrombin generation by attenuating prothrombin activation and thrombin feedback reactions
- (2009) C. A. Kretz et al. THROMBOSIS AND HAEMOSTASIS
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- (2008) J. MÜLLER et al. JOURNAL OF THROMBOSIS AND HAEMOSTASIS
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- (2007) Moonkyu Kang et al. BLOOD CELLS MOLECULES AND DISEASES
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