Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure

Autonomic, functional, skeletal muscle, and cardiac abnormalities are associated with increased ergoreflex sensitivity in mitochondrial disease

(2017) Alberto Giannoni et al.   EUROPEAN JOURNAL OF HEART FAILURE

Inflammatory signalling regulates eccentric contraction-induced protein synthesis in cachectic skeletal muscle

(2017) Justin P. Hardee et al.   Journal of Cachexia Sarcopenia and Muscle

Ethical guidelines for publishing in the journal of cachexia, sarcopenia and muscle: update 2017

(2017) Stephan von Haehling et al.   Journal of Cachexia Sarcopenia and Muscle

Acetylation and succinylation contribute to maturational alterations in energy metabolism in the newborn heart

(2016) Arata Fukushima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Acetylation control of cardiac fatty acid β-oxidation and energy metabolism in obesity, diabetes, and heart failure

(2016) Arata Fukushima et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dipeptidyl peptidase-4 inhibitor improved exercise capacity and mitochondrial biogenesis in mice with heart failure via activation of glucagon-like peptide-1 receptor signalling

(2016) Shingo Takada et al.   CARDIOVASCULAR RESEARCH

The influence of iron deficiency on the functioning of skeletal muscles: experimental evidence and clinical implications

(2016) Magdalena Stugiewicz et al.   EUROPEAN JOURNAL OF HEART FAILURE

The impact of ageing, physical activity, and pre-frailty on skeletal muscle phenotype, mitochondrial content, and intramyocellular lipids in men

(2016) Félix St-Jean-Pelletier et al.   Journal of Cachexia Sarcopenia and Muscle

SIRT3 deficiency impairs mitochondrial and contractile function in the heart

(2015) Christoph Koentges et al.   BASIC RESEARCH IN CARDIOLOGY

Mitochondrial complex I defect and increased fatty acid oxidation enhance protein lysine acetylation in the diabetic heart

(2015) Edwin J. Vazquez et al.   CARDIOVASCULAR RESEARCH

Maximal Oxidative Capacity during Exercise Is Associated with Skeletal Muscle Fuel Selection and Dynamic Changes in Mitochondrial Protein Acetylation

(2015) Katherine A. Overmyer et al.   Cell Metabolism

Myocardial Energy Substrate Metabolism in Heart Failure : from Pathways to Therapeutic Targets

(2015) Arata Fukushima et al.   CURRENT PHARMACEUTICAL DESIGN

Skeletal Muscle Abnormalities in Heart Failure

(2015) Shintaro Kinugawa et al.   International Heart Journal

Metabolic Disturbances Identified in Plasma Are Associated With Outcomes in Patients With Heart Failure

(2015) Mei-Ling Cheng et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3

(2015) Vinodkumar B. Pillai et al.   Nature Communications

Mouse SIRT3 Attenuates Hypertrophy-Related Lipid Accumulation in the Heart through the Deacetylation of LCAD

(2015) Tongshuai Chen et al.   PLoS One

Metabolomic Fingerprint of Heart Failure with Preserved Ejection Fraction

(2015) Beshay N. Zordoky et al.   PLoS One

(Pro)renin receptor in skeletal muscle is involved in the development of insulin resistance associated with postinfarct heart failure in mice

(2014) Arata Fukushima et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

(2014) Osama Abo Alrob et al.   CARDIOVASCULAR RESEARCH

Targeting of High Peak Respiratory Exchange Ratio Is Safe and Enhances the Prognostic Power of Peak Oxygen Uptake for Heart Failure Patients

(2014) Michio Nakanishi et al.   CIRCULATION JOURNAL

Energy Metabolic Reprogramming in the Hypertrophied and Early Stage Failing Heart

(2014) Ling Lai et al.   Circulation-Heart Failure

Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin

(2014) S. Gao et al.   DIABETES

Lowering Body Weight in Obese Mice With Diastolic Heart Failure Improves Cardiac Insulin Sensitivity and Function: Implications for the Obesity Paradox

(2014) Sowndramalingam Sankaralingam et al.   DIABETES

Intramyocellular lipid is increased in the skeletal muscle of patients with dilated cardiomyopathy with lowered exercise capacity

(2014) Kagami Hirabayashi et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Metabolic Impairment in Heart Failure

(2014) Wolfram Doehner et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The growing landscape of lysine acetylation links metabolism and cell signalling

(2014) Chunaram Choudhary et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ANG II causes insulin resistance and induces cardiac metabolic switch and inefficiency: a critical role of PDK4

(2013) Jun Mori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure

(2013) Georgios Karamanlidis et al.   Cell Metabolism

Sirt3 Regulates Metabolic Flexibility of Skeletal Muscle Through Reversible Enzymatic Deacetylation

(2013) E. Jing et al.   DIABETES

Systemic Oxidative Stress Is Associated With Lower Aerobic Capacity and Impaired Skeletal Muscle Energy Metabolism in Patients With Metabolic Syndrome

(2013) T. Yokota et al.   DIABETES CARE

The ‘skeletal muscle hypothesis in heart failure’ revised

(2013) Massimo F. Piepoli et al.   EUROPEAN HEART JOURNAL

Decreased serum brain-derived neurotrophic factor levels are correlated with exercise intolerance in patients with heart failure

(2013) Arata Fukushima et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Angiotensin II receptor blocker improves the lowered exercise capacity and impaired mitochondrial function of the skeletal muscle in type 2 diabetic mice

(2013) Shingo Takada et al.   JOURNAL OF APPLIED PHYSIOLOGY

Head-to-Head Comparison of 2 Myocardial Fibrosis Biomarkers for Long-Term Heart Failure Risk Stratification

(2013) Antoni Bayes-Genis et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways

(2013) M. J. Rardin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Animal Models of Heart Failure

(2012) Steven R. Houser et al.   CIRCULATION RESEARCH

Muscle wasting in patients with chronic heart failure: results from the studies investigating co-morbidities aggravating heart failure (SICA-HF)

(2012) S. Fulster et al.   EUROPEAN HEART JOURNAL

Plasma asymmetric dimethylarginine and mortality in patients with acute decompensation of chronic heart failure

(2012) Michael N Zairis et al.   HEART

Posttranslational modifications control FoxO3 activity during denervation

(2011) Enrico Bertaggia et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

(2011) E. Jing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinician’s Guide to Cardiopulmonary Exercise Testing in Adults

(2010) Gary J. Balady et al.   CIRCULATION

SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

(2010) Matthew D. Hirschey et al.   NATURE

Myocardial Fatty Acid Metabolism in Health and Disease

(2010) Gary D. Lopaschuk et al.   PHYSIOLOGICAL REVIEWS

Regulation of Cellular Metabolism by Protein Lysine Acetylation

(2010) S. Zhao et al.   SCIENCE

Metabolomic Profiling of Anionic Metabolites by Capillary Electrophoresis Mass Spectrometry

(2009) Tomoyoshi Soga et al.   ANALYTICAL CHEMISTRY

Quantitative Metabolome Profiling of Colon and Stomach Cancer Microenvironment by Capillary Electrophoresis Time-of-Flight Mass Spectrometry

(2009) A. Hirayama et al.   CANCER RESEARCH

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD + Synthesis in Cardiac Myocytes

(2009) Chiao-Po Hsu et al.   CIRCULATION RESEARCH

Efficacy and Safety of Exercise Training in Patients With Chronic Heart Failure

(2009) Christopher M. O’Connor et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Exogenous NAD Blocks Cardiac Hypertrophic Response via Activation of the SIRT3-LKB1-AMP-activated Kinase Pathway

(2009) Vinodkumar B. Pillai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Label-free, normalized quantification of complex mass spectrometry data for proteomic analysis

(2009) Noelle M Griffin et al.   NATURE BIOTECHNOLOGY