Functional changes in the neural retina occur in the absence of mitochondrial dysfunction in a rodent model of diabetic retinopathy

Hypoxia induces heart regeneration in adult mice

(2017) Yuji Nakada et al.   NATURE

Diabetic retinopathy is a neurodegenerative disorder

(2017) Stephanie K. Lynch et al.   VISION RESEARCH

Loss of the antioxidant enzyme CuZnSOD (Sod1) mimics an age-related increase in absolute mitochondrial DNA copy number in the skeletal muscle

(2016) Dustin R. Masser et al.   AGE

Mitochondrial DNA exhibits resistance to induced point and deletion mutations

(2016) William J. Valente et al.   NUCLEIC ACIDS RESEARCH

Retinal neurodegeneration may precede microvascular changes characteristic of diabetic retinopathy in diabetes mellitus

(2016) Elliott H. Sohn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The progress in understanding and treatment of diabetic retinopathy

(2016) Alan W. Stitt et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Oxidative stress, mitochondrial damage and diabetic retinopathy

(2015) Renu A. Kowluru et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A mitochondrial therapeutic reverses visual decline in mouse models of diabetes

(2015) N. M. Alam et al.   Disease Models & Mechanisms

The dynamics of mitochondrial DNA heteroplasmy: implications for human health and disease

(2015) James B. Stewart et al.   NATURE REVIEWS GENETICS

In the Early Stages of Diabetes, Rat Retinal Mitochondria Undergo Mild Uncoupling due to UCP2 Activity

(2015) Ixchel Osorio-Paz et al.   PLoS One

Diabetic retinopathy: loss of neuroretinal adaptation to the diabetic metabolic environment

(2014) Steven F. Abcouwer et al.   Annals of the New York Academy of Sciences

Effect of Intensive Diabetes Therapy on the Progression of Diabetic Retinopathy in Patients With Type 1 Diabetes: 18 Years of Follow-up in the DCCT/EDIC

(2014)   DIABETES

Insulin treatment normalizes retinal neuroinflammation but not markers of synapse loss in diabetic rats

(2014) Dustin R. Masser et al.   EXPERIMENTAL EYE RESEARCH

Extensive pathogenicity of mitochondrial heteroplasmy in healthy human individuals

(2014) K. Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rodent Hyperglycemia-Induced Inner Retinal Deficits are Mirrored in Human Diabetes

(2014) Machelle T. Pardue et al.   Translational Vision Science & Technology

Mitochondrial quality control in neurodegenerative diseases

(2013) Luc Dupuis   BIOCHIMIE

Topical Administration of Somatostatin Prevents Retinal Neurodegeneration in Experimental Diabetes

(2013) C. Hernandez et al.   DIABETES

Diabetic Retinopathy and Other Ocular Findings in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study

(2013) Lloyd Paul Aiello et al.   DIABETES CARE

Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina

(2013) Y. Du et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Focused, high accuracy 5-methylcytosine quantitation with base resolution by benchtop next-generation sequencing

(2013) Dustin R Masser et al.   Epigenetics & Chromatin

Damaged Mitochondrial DNA Replication System and the Development of Diabetic Retinopathy

(2012) Shikha Tewari et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial Dysfunction in Retinal Diseases

(2012) Megha Barot et al.   CURRENT EYE RESEARCH

A compensatory mechanism protects retinal mitochondria from initial insult in diabetic retinopathy

(2012) Julia M. Santos et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chronic insulin treatment of diabetes does not fully normalize alterations in the retinal transcriptome

(2011) Georgina V Bixler et al.   BMC Medical Genomics

Inner retinal visual dysfunction is a sensitive marker of non-proliferative diabetic retinopathy

(2011) Gregory R Jackson et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Multi-Modal Proteomic Analysis of Retinal Protein Expression Alterations in a Rat Model of Diabetic Retinopathy

(2011) Heather D. VanGuilder et al.   PLoS One

Role of Mitochondrial DNA Damage in the Development of Diabetic Retinopathy, and the Metabolic Memory Phenomenon Associated with Its Progression

(2010) Sally A. Madsen–Bouterse et al.   ANTIOXIDANTS & REDOX SIGNALING

Bioenergetic analysis of isolated cerebrocortical nerve terminals on a microgram scale: spare respiratory capacity and stochastic mitochondrial failure

(2009) Sung W. Choi et al.   JOURNAL OF NEUROCHEMISTRY

A multistep validation process of biomarkers for preclinical drug development

(2009) W M Freeman et al.   PHARMACOGENOMICS JOURNAL

Whole genome assessment of the retinal response to diabetes reveals a progressive neurovascular inflammatory response

(2008) Robert M Brucklacher et al.   BMC Medical Genomics

Diabetes downregulates presynaptic proteins and reduces basal synapsin I phosphorylation in rat retina

(2008) Heather D. VanGuilder et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Oxidative stress and diabetic retinopathy: Pathophysiological mechanisms and treatment perspectives

(2008) Sally A. Madsen-Bouterse et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS