Metabolic Glycoengineering with N -Acyl Side Chain Modified Mannosamines

Fragment screening of N-acetylmannosamine kinase reveals noncarbohydrate inhibitors

(2016) Jonas Aretz et al.   CANADIAN JOURNAL OF CHEMISTRY

A sequential bioorthogonal dual strategy: ManNAl and SiaNAl as distinct tools to unravel sialic acid metabolic pathways

(2016) P. A. Gilormini et al.   CHEMICAL COMMUNICATIONS

Inhibition of the key enzyme of sialic acid biosynthesis by C6-Se modified N-acetylmannosamine analogs

(2016) Olaia Nieto-Garcia et al.   Chemical Science

Sialic Acid Glycoengineering Using an Unnatural Sialic Acid for the Detection of Sialoglycan Biosynthesis Defects and On-Cell Synthesis of Siglec Ligands

(2015) Christian Büll et al.   ACS Chemical Biology

Labeling Cell Surface GPIs and GPI-Anchored Proteins through Metabolic Engineering with Artificial Inositol Derivatives

(2015) Lili Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chemical Remodeling of Cell-Surface Sialic Acids through a Palladium-Triggered Bioorthogonal Elimination Reaction

(2015) Jie Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

LC–MS/MS glycomic analyses of free and conjugated forms of the sialic acids, Neu5Ac, Neu5Gc and KDN in human throat cancers

(2015) Fang Wang et al.   GLYCOBIOLOGY

Molecular characterization and expression analyses of ST8Sia II and IV in piglets during postnatal development: lack of correlation between transcription and posttranslational levels

(2015) Xi Zhu et al.   GLYCOCONJUGATE JOURNAL

Mouse Siglec-1 Mediatestrans-Infection of Surface-bound Murine Leukemia Virus in a Sialic AcidN-Acyl Side Chain-dependent Manner

(2015) Elina Erikson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Bioorthogonal Ligation of Cyclopropenones Mediated by Triarylphosphines

(2015) Hui-Wen Shih et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rapid probing of sialylated glycoproteins in vitro and in vivo via metabolic oligosaccharide engineering of a minimal cyclopropene reporter

(2015) De-Cai Xiong et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A novel cancer immunotherapy based on the combination of a synthetic carbohydrate-pulsed dendritic cell vaccine and glycoengineered cancer cells

(2015) Lei Qiu et al.   Oncotarget

PolySia-Specific Retargeting of Oncolytic Viruses Triggers Tumor-Specific Immune Responses and Facilitates Therapy of Disseminated Lung Cancer

(2015) A. Kloos et al.   Cancer Immunology Research

Identification of sialylated glycoproteins from metabolically oligosaccharide engineered pancreatic cells

(2015) Yuan Tian et al.   Clinical Proteomics

Rapid and Specific Enrichment of Culturable Gram Negative Bacteria Using Non-Lethal Copper-Free Click Chemistry Coupled with Magnetic Beads Separation

(2015) Emilie Fugier et al.   PLoS One

Chemical Tumor-Targeting of Nanoparticles Based on Metabolic Glycoengineering and Click Chemistry

(2014) Sangmin Lee et al.   ACS Nano

Fluorescent Mimetics of CMP-Neu5Ac Are Highly Potent, Cell-Permeable Polarization Probes of Eukaryotic and Bacterial Sialyltransferases and Inhibit Cellular Sialylation

(2014) Johannes J. Preidl et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Identification of LivingLegionella pneumophilaUsing Species-Specific Metabolic Lipopolysaccharide Labeling

(2014) Jordi Mas Pons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Preparation of Well-Defined Antibody-Drug Conjugates through Glycan Remodeling and Strain-Promoted Azide-Alkyne Cycloadditions

(2014) Xiuru Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sweet escape: Sialic acids in tumor immune evasion

(2014) Christian Büll et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Monitoring Dynamic Glycosylation in Vivo Using Supersensitive Click Chemistry

(2014) Hao Jiang et al.   BIOCONJUGATE CHEMISTRY

Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

(2014) Diego O. Croci et al.   CELL

Terminal Alkenes as Versatile Chemical Reporter Groups for Metabolic Oligosaccharide Engineering

(2014) Anne-Katrin Späte et al.   CHEMISTRY-A EUROPEAN JOURNAL

Polysialic acid/neural cell adhesion molecule modulates the formation of ductular reactions in liver injury

(2014) Atsunori Tsuchiya et al.   HEPATOLOGY

A Novel Approach to Decrease Sialic Acid Expression in Cells by a C-3-modifiedN-Acetylmannosamine

(2014) Paul R. Wratil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Systemic Blockade of Sialylation in Mice with a Global Inhibitor of Sialyltransferases

(2014) Matthew S. Macauley et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polysialic Acid, a Glycan with Highly Restricted Expression, Is Found on Human and Murine Leukocytes and Modulates Immune Responses

(2014) P. M. Drake et al.   JOURNAL OF IMMUNOLOGY

Changes in Metabolic Chemical Reporter Structure Yield a Selective Probe of O-GlcNAc Modification

(2014) Kelly N. Chuh et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Glycan Imaging in Intact Rat Hearts and Glycoproteomic Analysis Reveal the Upregulation of Sialylation during Cardiac Hypertrophy

(2014) Jie Rong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure Analysis of the Major Capsid Proteins of Human Polyomaviruses 6 and 7 Reveals an Obstructed Sialic Acid Binding Site

(2014) L. J. Stroh et al.   JOURNAL OF VIROLOGY

Improved cyclopropene reporters for probing protein glycosylation

(2014) David M. Patterson et al.   Molecular BioSystems

The sweet spot: defining virus–sialic acid interactions

(2014) Jennifer E. Stencel-Baerenwald et al.   NATURE REVIEWS MICROBIOLOGY

Sialic Acid Metabolic Engineering: A Potential Strategy for the Neuroblastoma Therapy

(2014) Vinayaga S. Gnanapragassam et al.   PLoS One

Cupulin Is a Zona Pellucida-Like Domain Protein and Major Component of the Cupula from the Inner Ear

(2014) Jens Dernedde et al.   PLoS One

A red meat-derived glycan promotes inflammation and cancer progression

(2014) Annie N. Samraj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialic Acid Rescues Repurified Lipopolysaccharide-Induced Acute Renal Failure via Inhibiting TLR4/PKC/gp91-Mediated Endoplasmic Reticulum Stress, Apoptosis, Autophagy, and Pyroptosis Signaling

(2014) Chih-Ching Yang et al.   TOXICOLOGICAL SCIENCES

Highly accelerated inverse electron-demand cycloaddition of electron-deficient azides with aliphatic cyclooctynes

(2014) Jan Dommerholt et al.   Nature Communications

Cell Labeling and Tracking Method without Distorted Signals by Phagocytosis of Macrophages

(2014) Sun-Woong Kang et al.   Theranostics

HIV-1 Capture and Transmission by Dendritic Cells: The Role of Viral Glycolipids and the Cellular Receptor Siglec-1

(2014) Nuria Izquierdo-Useros et al.   PLoS Pathogens

On-Chip Synthesis and Screening of a Sialoside Library Yields a High Affinity Ligand for Siglec-7

(2013) Cory D. Rillahan et al.   ACS Chemical Biology

Two-Color Glycan Labeling of Live Cells by a Combination of Diels-Alder and Click Chemistry

(2013) Andrea Niederwieser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Imaging Cell Surface Glycosylation in Vivo Using “Double Click” Chemistry

(2013) André A. Neves et al.   BIOCONJUGATE CHEMISTRY

Rapid Labeling of Metabolically Engineered Cell-Surface Glycoconjugates with a Carbamate-Linked Cyclopropene Reporter

(2013) Anne-Katrin Späte et al.   BIOCONJUGATE CHEMISTRY

Metabolic Glycan Imaging by Isonitrile-Tetrazine Click Chemistry

(2013) Shaun Stairs et al.   CHEMBIOCHEM

Fluorescent Live-Cell Imaging of Metabolically Incorporated Unnatural Cyclopropene-Mannosamine Derivatives

(2013) Christian M. Cole et al.   CHEMBIOCHEM

Alkynyl monosaccharide analogues as a tool for evaluating Golgi glycosylation efficiency: application to Congenital Disorders of Glycosylation (CDG)

(2013) Jorick Vanbeselaere et al.   CHEMICAL COMMUNICATIONS

Metabolic glycoengineering of Staphylococcus aureus reduces its adherence to human T24 bladder carcinoma cells

(2013) Elisabeth Memmel et al.   CHEMICAL COMMUNICATIONS

Positive Regulation of Insulin Signaling by Neuraminidase 1

(2013) L. Dridi et al.   DIABETES

Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine

(2013) Suvi Natunen et al.   GLYCOBIOLOGY

Stimulation of human peripheral blood mononuclear cells by the sialic acid precursor N-propanoylmannosamine

(2013) Cora Roehlecke et al.   GLYCOCONJUGATE JOURNAL

Hyaluronan Synthase 1 (HAS1) Requires Higher Cellular UDP-GlcNAc Concentration than HAS2 and HAS3

(2013) Kirsi Rilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bifunctional Unnatural Sialic Acids for Dual Metabolic Labeling of Cell-Surface Sialylated Glycans

(2013) Lianshun Feng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Artificial and Natural Sialic Acid Precursors Influence the Angiogenic Capacity of Human Umbilical Vein Endothelial Cells

(2013) Nils Bayer et al.   MOLECULES

Polysialic Acid: Versatile Modification of NCAM, SynCAM 1 and Neuropilin-2

(2013) Martina Mühlenhoff et al.   NEUROCHEMICAL RESEARCH

Dual-sugar imaging using isonitrile and azido-based click chemistries

(2013) Yéléna A. Wainman et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Short-Chain Fatty Acid-Modified Hexosamine for Tissue-Engineering Osteoarthritic Cartilage

(2013) Jeannine M. Coburn et al.   TISSUE ENGINEERING PART A

H5N1 receptor specificity as a factor in pandemic risk

(2013) James C. Paulson et al.   VIRUS RESEARCH

Interferon-Inducible Mechanism of Dendritic Cell-Mediated HIV-1 Dissemination Is Dependent on Siglec-1/CD169

(2013) Wendy Blay Puryear et al.   PLoS Pathogens

N-Propionyl polysialic acid precursor enhances the susceptibility of multiple myeloma to antitumor effect of anti-NprPSA monoclonal antibody

(2012) Hong Xiong et al.   ACTA PHARMACOLOGICA SINICA

Cell surface glycoprotein profiling of cancer cells based on bioorthogonal chemistry

(2012) Peng-wei Pan et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Glycan-Specific Metabolic Oligosaccharide Engineering of C7-Substituted Sialic Acids

(2012) Heinz Möller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triple Bioorthogonal Ligation Strategy for Simultaneous Labeling of Multiple Enzymatic Activities

(2012) Lianne I. Willems et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genetically Encoded Cyclopropene Directs Rapid, Photoclick-Chemistry-Mediated Protein Labeling in Mammalian Cells

(2012) Zhipeng Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Copper-Free Click Chemistry In Vivo for Tumor-Targeted Delivery of Nanoparticles

(2012) Heebeom Koo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Click-Mediated Labeling of Bacterial Membranes through Metabolic Modification of the Lipopolysaccharide Inner Core

(2012) Audrey Dumont et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Polysialylation of the neural cell adhesion molecule: Interfering with polysialylation and migration in neuroblastoma cells

(2012) Anja Seifert et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Extracellular and intracellular esterase processing of SCFA–hexosamine analogs: Implications for metabolic glycoengineering and drug delivery

(2012) Mohit P. Mathew et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Trypanosoma cruzi trans-sialidase as a multifunctional enzyme in Chagas’ disease

(2012) Sergio S. C. dC-Rubin et al.   CELLULAR MICROBIOLOGY

Chemical Synthesis and Enzymatic Testing of CMP-Sialic Acid Derivatives

(2012) Saskia Wolf et al.   CHEMBIOCHEM

Imaging the Sialome during Zebrafish Development with Copper-Free Click Chemistry

(2012) Karen W. Dehnert et al.   CHEMBIOCHEM

N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation

(2012) Leslie A. Bateman et al.   CHEMICAL COMMUNICATIONS

Metabolic monosaccharides altered cell responses to anticancer drugs

(2012) Long Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Mammalian sialidases: Physiological and pathological roles in cellular functions

(2012) T. Miyagi et al.   GLYCOBIOLOGY

Helicobacter pylori Infection Impairs the Mucin Production Rate and Turnover in the Murine Gastric Mucosa

(2012) Nazanin Navabi et al.   INFECTION AND IMMUNITY

Crystal Structures ofN-Acetylmannosamine Kinase Provide Insights into Enzyme Activity and Inhibition

(2012) Jacobo Martinez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sialic Acid Associated with αvβ3Integrin Mediates HIV-1 Tat Protein Interaction and Endothelial Cell Proangiogenic Activation

(2012) Paola Chiodelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functionalized Cyclopropenes As Bioorthogonal Chemical Reporters

(2012) David M. Patterson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cell-Selective Metabolic Glycan Labeling Based on Ligand-Targeted Liposomes

(2012) Ran Xie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structural Basis of Rotavirus Strain Preference toward N-Acetyl- or N-Glycolylneuraminic Acid-Containing Receptors

(2012) X. Yu et al.   JOURNAL OF VIROLOGY

Metabolic Flux Increases Glycoprotein Sialylation: Implications for Cell Adhesion and Cancer Metastasis

(2012) Ruben T. Almaraz et al.   MOLECULAR & CELLULAR PROTEOMICS

Global metabolic inhibitors of sialyl- and fucosyltransferases remodel the glycome

(2012) Cory D Rillahan et al.   Nature Chemical Biology

Metabolic Labeling of Caenorhabditis elegans Primary Embryonic Cells with Azido-Sugars as a Tool for Glycoprotein Discovery

(2012) Amanda R. Burnham-Marusich et al.   PLoS One

The role of sialic acid as a modulator of the anti-inflammatory activity of IgG

(2012) Sybille Böhm et al.   Seminars in Immunopathology

Siglec-1 Is a Novel Dendritic Cell Receptor That Mediates HIV-1 Trans-Infection Through Recognition of Viral Membrane Gangliosides

(2012) Nuria Izquierdo-Useros et al.   PLOS BIOLOGY

Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection

(2012) Ursula Neu et al.   PLoS Pathogens

From Mechanism to Mouse: A Tale of Two Bioorthogonal Reactions

(2011) Ellen M. Sletten et al.   ACCOUNTS OF CHEMICAL RESEARCH

High-Throughput Screening for Inhibitors of Sialyl- and Fucosyltransferases

(2011) Cory D. Rillahan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging

(2011) Mark R. Karver et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Increasing the Efficacy of Bioorthogonal Click Reactions for Bioconjugation: A Comparative Study

(2011) Christen Besanceney-Webler et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, synthesis and the effect of 1,2,3-triazole sialylmimetic neoglycoconjugates on Trypanosoma cruzi and its cell surface trans-sialidase

(2011) Vanessa L. Campo et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Modified GM3 gangliosides produced by metabolic oligosaccharide engineering

(2011) Chad M. Whitman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemical control of metabolically-engineered voltage-gated K+ channels

(2011) Zhengmao Hua et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Deciphering glycan linkages involved in Jurkat cell interactions with gold-coated nanofibers via sugar-displayed thiols

(2011) Jian Du et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Homeostatic regulation of NCAM polysialylation is critical for correct synaptic targeting

(2011) Johannes Vogt et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Strain-Promoted Alkyne-Azide Cycloadditions (SPAAC) Reveal New Features of Glycoconjugate Biosynthesis

(2011) Ngalle Eric Mbua et al.   CHEMBIOCHEM

Viruses and sialic acids: rules of engagement

(2011) Ursula Neu et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Imaging sialylated tumor cell glycans in vivo

(2011) André A. Neves et al.   FASEB JOURNAL

Biochemical engineering of theN-acyl side chain of sialic acids alters the kinetics of a glycosylated potassium channel Kv3.1

(2011) M. Kristen Hall et al.   FEBS LETTERS

Invasion of Trypanosoma cruzi into host cells is impaired by N-propionylmannosamine and other N-acylmannosamines

(2011) Thorsten Lieke et al.   GLYCOCONJUGATE JOURNAL

Where catabolism meets signalling: neuraminidase 1 as a modulator of cell receptors

(2011) Alexey V. Pshezhetsky et al.   GLYCOCONJUGATE JOURNAL

Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells

(2011) S. P. Thankamony et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The i Blood Group Antigen as a Marker for Umbilical Cord Blood-Derived Mesenchymal Stem Cells

(2011) Tia Hirvonen et al.   STEM CELLS AND DEVELOPMENT

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rolling Cell Adhesion

(2010) Rodger P. McEver et al.   Annual Review of Cell and Developmental Biology

Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

(2010) Arne Homann et al.   Beilstein Journal of Organic Chemistry

Labeling Live Cells by Copper-Catalyzed Alkyne−Azide Click Chemistry

(2010) Vu Hong et al.   BIOCONJUGATE CHEMISTRY

Two-Step Labeling of Endogenous Enzymatic Activities by Diels-Alder Ligation

(2010) Lianne I. Willems et al.   CHEMBIOCHEM

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

Electrostatic Cell-Surface Repulsion Initiates Lumen Formation in Developing Blood Vessels

(2010) Boris Strilić et al.   CURRENT BIOLOGY

A new class of mechanism-based inhibitors for Trypanosoma cruzi trans-sialidase and their influence on parasite virulence

(2010) S. T. Carvalho et al.   GLYCOBIOLOGY

Identification of glycoproteins targeted by Trypanosoma cruzi trans-sialidase, a virulence factor that disturbs lymphocyte glycosylation

(2010) R. P. Muia et al.   GLYCOBIOLOGY

Emerging Role of α2,6-Sialic Acid as a Negative Regulator of Galectin Binding and Function

(2010) Ya Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biocompatible Copper(I) Catalysts for in Vivo Imaging of Glycans

(2010) David Soriano del Amo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Metabolically incorporated photocrosslinking sialic acid covalently captures a ganglioside–protein complex

(2010) Michelle R. Bond et al.   Molecular BioSystems

Synaptic cell adhesion molecule SynCAM 1 is a target for polysialylation in postnatal mouse brain

(2010) S. P. Galuska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sialidase enhances recovery from spinal cord contusion injury

(2010) A. Mountney et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Copper-free click chemistry in living animals

(2010) P. V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In VivoImaging ofCaenorhabditis elegansGlycans

(2009) Scott T. Laughlin et al.   ACS Chemical Biology

Analysis and Optimization of Copper-Catalyzed Azide–Alkyne Cycloaddition for Bioconjugation

(2009) Vu Hong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regulation and pathophysiological implications of UDP-GlcNAc 2-epimerase/ManNAc kinase (GNE) as the key enzyme of sialic acid biosynthesis

(2009) Stefan O. Reinke et al.   BIOLOGICAL CHEMISTRY

Hexosamine analogs: from metabolic glycoengineering to drug discovery

(2009) Zhiyun Wang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Sialic acids as regulators of molecular and cellular interactions

(2009) Roland Schauer   CURRENT OPINION IN STRUCTURAL BIOLOGY

Lessons from GNE-deficient embryonic stem cells: sialic acid biosynthesis is involved in proliferation and gene expression

(2009) Wenke Weidemann et al.   GLYCOBIOLOGY

Metabolic glycoengineering: Sialic acid and beyond

(2009) Jian Du et al.   GLYCOBIOLOGY

Vaccines Containing de- N -Acetyl Sialic Acid Elicit Antibodies Protective against Neisseria meningitidis Groups B and C

(2009) Gregory R. Moe et al.   JOURNAL OF IMMUNOLOGY

Hexosamine Template. A Platform for Modulating Gene Expression and for Sugar-Based Drug Discovery

(2009) Noha Elmouelhi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Hexosamine flux, the O-GlcNAc modification, and the development of insulin resistance in adipocytes

(2009) Chin Fen Teo et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Photocrosslinking of glycoconjugates using metabolically incorporated diazirine-containing sugars

(2009) Michelle R Bond et al.   Nature Protocols

Remodeling bacterial polysaccharides by metabolic pathway engineering

(2009) W. Yi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulated and aberrant glycosylation modulate cardiac electrical signaling

(2009) M. L. Montpetit et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SIALIC ACID REDUCES ACUTE ENDOTOXEMIA-INDUCED LIVER DYSFUNCTION IN THE RAT

(2009) Chien-Hsing Ho et al.   SHOCK

Regioisomeric SCFA Attachment to Hexosamines Separates Metabolic Flux from Cytotoxicity and MUC1 Suppression

(2008) Udayanath Aich et al.   ACS Chemical Biology

A New Generation of SpecificTrypanosoma cruzi trans-Sialidase Inhibitors

(2008) Sabrina Buchini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A FRET-Based Fluorogenic Phosphine for Live-Cell Imaging with the Staudinger Ligation

(2008) Matthew J. Hangauer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Conformational Properties of Methyl α-(2,8)-Di/Trisialosides and TheirN-Acyl Analogues: Implications for Anti-Neisseria meningitidisB Vaccine Design†

(2008) Austin B. Yongye et al.   BIOCHEMISTRY

Fluorination of mammalian cell surfaces via the sialic acid biosynthetic pathway

(2008) Laila Dafik et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells

(2008) Maria Kontou et al.   GLYCOCONJUGATE JOURNAL

Neglected tropical cardiomyopathies: I. Chagas disease

(2008) S. Yacoub et al.   HEART

Sialylation of β1 Integrins Blocks Cell Adhesion to Galectin-3 and Protects Cells against Galectin-3-induced Apoptosis

(2008) Ya Zhuo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Galectin-1, -2, and -3 Exhibit Differential Recognition of Sialylated Glycans and Blood Group Antigens

(2008) Sean R. Stowell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Impact of Meningococcal Serogroup C Conjugate Vaccines on Carriage and Herd Immunity

(2008) Martin C. J. Maiden et al.   JOURNAL OF INFECTIOUS DISEASES

Expression of sialyltransferase activity on intact human neutrophils

(2008) Salahaldin Rifat et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Targeting Pro-Invasive Oncogenes with Short Chain Fatty Acid-Hexosamine Analogues Inhibits the Mobility of Metastatic MDA-MB-231 Breast Cancer Cells

(2008) Christopher T. Campbell et al.   JOURNAL OF MEDICINAL CHEMISTRY

Photoactivatable Crosslinking Sugars for Capturing Glycoprotein Interactions

(2008) Yoshihito Tanaka et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ex vivo glycan engineering of CD44 programs human multipotent mesenchymal stromal cell trafficking to bone

(2008) Robert Sackstein et al.   NATURE MEDICINE

Imaging the glycome

(2008) S. T. Laughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish

(2008) S. T. Laughlin et al.   SCIENCE

Sialic acids in human health and disease

(2008) Ajit Varki   TRENDS IN MOLECULAR MEDICINE

N-Propanoylmannosamine interferes with O-GlcNAc modification of the tyrosine 3-monooxygenase and stimulates dopamine secretion

(2007) Kaya Bork et al.   JOURNAL OF NEUROSCIENCE RESEARCH