Bioorthogonal Reaction Pairs Enable Simultaneous, Selective, Multi-Target Imaging

Synthesis and In Vivo Imaging of a 18F-Labeled PARP1 Inhibitor Using a Chemically Orthogonal Scavenger-Assisted High-Performance Method

(2011) Thomas Reiner et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Evaluation of a Series of 1,2,4,5-Tetrazines for Bioorthogonal Conjugation

(2011) Mark R. Karver et al.   BIOCONJUGATE CHEMISTRY

(E,E)-1,5-Cyclooctadiene: a small and fast click-chemistry multitalent

(2011) Henning Stöckmann et al.   CHEMICAL COMMUNICATIONS

Micro-NMR for Rapid Molecular Analysis of Human Tumor Samples

(2011) J. B. Haun et al.   Science Translational Medicine

Readily Accessible Bicyclononynes for Bioorthogonal Labeling and Three-Dimensional Imaging of Living Cells

(2010) Jan Dommerholt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Vivo Chemistry for Pretargeted Tumor Imaging in Live Mice

(2010) Raffaella Rossin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioorthogonal Turn-On Probes for Imaging Small Molecules inside Living Cells

(2010) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine–trans-cyclooctene ligation for the rapid construction of 18F labeled probes

(2010) Zibo Li et al.   CHEMICAL COMMUNICATIONS

Cu-free click cycloaddition reactions in chemical biology

(2010) John C. Jewett et al.   CHEMICAL SOCIETY REVIEWS

Metal-Free Sequential [3 + 2]-Dipolar Cycloadditions using Cyclooctynes and 1,3-Dipoles of Different Reactivity

(2010) Brian C. Sanders et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioorthogonal chemistry amplifies nanoparticle binding and enhances the sensitivity of cell detection

(2010) Jered B. Haun et al.   Nature Nanotechnology

Copper-free click chemistry in living animals

(2010) P. V. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and Sensitive Pretargeted Labeling of Cancer Cells through a Tetrazine/trans-Cyclooctene Cycloaddition

(2009) Neal K. Devaraj et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aza-dibenzocyclooctynes for fast and efficient enzyme PEGylation via copper-free (3+2) cycloaddition

(2009) Marjoke F. Debets et al.   CHEMICAL COMMUNICATIONS

Visualizing Metabolically Labeled Glycoconjugates of Living Cells by Copper-Free and Fast Huisgen Cycloadditions

(2008) Xinghai Ning et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dual Labeling of Biomolecules by Using Click Chemistry: A Sequential Approach

(2008) Péter Kele et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tetrazine-Based Cycloadditions: Application to Pretargeted Live Cell Imaging

(2008) Neal K. Devaraj et al.   BIOCONJUGATE CHEMISTRY

Tetrazine Ligation: Fast Bioconjugation Based on Inverse-Electron-Demand Diels−Alder Reactivity

(2008) Melissa L. Blackman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Hydrophilic Azacyclooctyne for Cu-Free Click Chemistry

(2008) Ellen M. Sletten et al.   ORGANIC LETTERS