Protein misfolding and aggregation in neurodegenerative diseases: a review of pathogeneses, novel detection strategies, and potential therapeutics
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Title
Protein misfolding and aggregation in neurodegenerative diseases: a review of pathogeneses, novel detection strategies, and potential therapeutics
Authors
Keywords
-
Journal
REVIEWS IN THE NEUROSCIENCES
Volume -, Issue -, Pages -
Publisher
Walter de Gruyter GmbH
Online
2019-02-11
DOI
10.1515/revneuro-2016-0035
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- (2018) Robert H Scannevin CURRENT OPINION IN CHEMICAL BIOLOGY
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- Binding affinity of amyloid oligomers to cellular membranes is a generic indicator of cellular dysfunction in protein misfolding diseases
- (2016) Elisa Evangelisti et al. Scientific Reports
- 2015 Alzheimer's disease facts and figures
- (2015) Alzheimers & Dementia
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- (2015) Greet De Baets et al. BIOINFORMATICS
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- (2015) J. J. Greenlee et al. ILAR JOURNAL
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- (2015) Pietro Sormanni et al. JOURNAL OF MOLECULAR BIOLOGY
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- 2013 Alzheimer's disease facts and figures
- (2013) Alzheimers & Dementia
- Huntington's disease: underlying molecular mechanisms and emerging concepts
- (2013) John Labbadia et al. TRENDS IN BIOCHEMICAL SCIENCES
- Mechanisms, models and biomarkers in amyotrophic lateral sclerosis
- (2013) Martin R. Turner et al. Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration
- Amyotrophic Lateral Sclerosis: An update for 2013 Clinical Features, Pathophysiology, Management and Therapeutic Trials
- (2013) Paul Gordon et al. Aging and Disease
- The Ever Expanding Spinocerebellar Ataxias. Editorial
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- Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation
- (2012) Igor F. Tsigelny et al. FEBS Journal
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- The unfolded protein response: controlling cell fate decisions under ER stress and beyond
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- Ion channels induced by the prion protein
- (2012) Isaac H. Solomon et al. Prion
- Tafamidis, a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade
- (2012) C. E. Bulawa et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Neurodegeneration as a consequence of failed mitochondrial maintenance
- (2011) Mariusz Karbowski et al. ACTA NEUROPATHOLOGICA
- Parkinson's Disease: Genetics and Pathogenesis
- (2011) Joshua M. Shulman et al. Annual Review of Pathology-Mechanisms of Disease
- Amyotrophic lateral sclerosis
- (2011) Matthew C Kiernan et al. LANCET
- Molecular chaperones in protein folding and proteostasis
- (2011) F. Ulrich Hartl et al. NATURE
- The Revitalized Tau Hypothesis on Alzheimer's Disease
- (2010) Ricardo B. Maccioni et al. ARCHIVES OF MEDICAL RESEARCH
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- Generating a Prion with Bacterially Expressed Recombinant Prion Protein
- (2010) F. Wang et al. SCIENCE
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- (2009) S. Lesage et al. HUMAN MOLECULAR GENETICS
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- (2009) Anatoly Nikolaev et al. NATURE
- The ribosome as a platform for co-translational processing, folding and targeting of newly synthesized proteins
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- Prion Diseases: From Protein to Cell Pathology
- (2008) Gabor G. Kovacs et al. AMERICAN JOURNAL OF PATHOLOGY
- Pathophysiology of Parkinsonism
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