Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity
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Title
Repositioning tolcapone as a potent inhibitor of transthyretin amyloidogenesis and associated cellular toxicity
Authors
Keywords
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Journal
Nature Communications
Volume 7, Issue -, Pages 10787
Publisher
Springer Nature
Online
2016-02-23
DOI
10.1038/ncomms10787
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- (2014) Lei Z. Robinson et al. BIOCHEMISTRY
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- (2013) Lei Zhao et al. BIOCHEMISTRY
- Effect on disability and safety of Tafamidis in late onset of Met30 transthyretin familial amyloid polyneuropathy
- (2013) P. Lozeron et al. EUROPEAN JOURNAL OF NEUROLOGY
- Tafamidis for transthyretin familial amyloid polyneuropathy: A randomized, controlled trial
- (2013) I. S. J. Merkies NEUROLOGY
- AG10 inhibits amyloidogenesis and cellular toxicity of the familial amyloid cardiomyopathy-associated V122I transthyretin
- (2013) S. C. Penchala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Transthyretin Amyloidoses: From Delineating the Molecular Mechanism of Aggregation Linked to Pathology to a Regulatory-Agency-Approved Drug
- (2012) Steven M. Johnson et al. JOURNAL OF MOLECULAR BIOLOGY
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- (2011) Steve Bourgault et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2011) Estefania P. C. Azevedo et al. BIOCHEMISTRY
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- Do enthalpy and entropy distinguish first in class from best in class?
- (2008) E FREIRE DRUG DISCOVERY TODAY
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- (2008) Steven M. Johnson et al. JOURNAL OF MEDICINAL CHEMISTRY
- Biochemical and Structural Evaluation of Highly Selective 2-Arylbenzoxazole-Based Transthyretin Amyloidogenesis Inhibitors
- (2007) Steven M. Johnson et al. JOURNAL OF MEDICINAL CHEMISTRY
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