The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins

Deciphering Protein O-Glycosylation: Solid-Phase Chemoenzymatic Cleavage and Enrichment

(2018) Shuang Yang et al.   ANALYTICAL CHEMISTRY

Effective Assignment of α2,3/α2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics

(2018) Christian Pett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment

(2018) María T. Elola et al.   CELLULAR IMMUNOLOGY

Physical biology of the cancer cell glycocalyx

(2018) Joe Chin-Hun Kuo et al.   Nature Physics

The benefits of hybrid fragmentation methods for glycoproteomics

(2018) Karli R. Reiding et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Mapping the O‐glycoproteome using site‐specific extraction of O‐linked glycopeptides (EXoO)

(2018) Weiming Yang et al.   Molecular Systems Biology

Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties

(2017) Huifeng Yu et al.   GLYCOBIOLOGY

Viewing Siglecs through the lens of tumor immunology

(2017) Isabella Fraschilla et al.   IMMUNOLOGICAL REVIEWS

Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer

(2017) Jos P.M. van Putten et al.   Journal of Innate Immunity

Recognition of protein-linked glycans as a determinant of peptidase activity

(2017) Ilit Noach et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

O-acetylation of the serine-rich repeat glycoprotein GspB is coordinated with accessory Sec transport

(2017) Ravin Seepersaud et al.   PLoS Pathogens

A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression

(2017) Elliot C Woods et al.   eLife

Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Cancer Cell Behaviors

(2017) Carolyn R. Shurer et al.   ACS Biomaterials-Science & Engineering

Genetically Encoded Toolbox for Glycocalyx Engineering: Tunable Control of Cell Adhesion, Survival, and Cancer Cell Behaviors

(2017) Carolyn R. Shurer et al.   ACS Biomaterials Science & Engineering

Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis

(2016) Spencer A. Freeman et al.   CELL

Engineered CAR T Cells Targeting the Cancer-Associated Tn-Glycoform of the Membrane Mucin MUC1 Control Adenocarcinoma

(2016) Avery D. Posey et al.   IMMUNITY

Engagement of distinct epitopes on CD43 induces different co-stimulatory pathways in human T cells

(2016) Madhura Modak et al.   IMMUNOLOGY

Protein O-Mannosylation in the Murine Brain: Occurrence of Mono-O-Mannosyl Glycans and Identification of New Substrates

(2016) Markus F. Bartels et al.   PLoS One

Precision glycocalyx editing as a strategy for cancer immunotherapy

(2016) Han Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints

(2016) Shohei Koyama et al.   Nature Communications

Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential

(2015) Padmanee Sharma et al.   CELL

Distinctive MS/MS Fragmentation Pathways of Glycopeptide-Generated Oxonium Ions Provide Evidence of the Glycan Structure

(2015) Jin Yu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Isotope-targeted glycoproteomics (IsoTaG): a mass-independent platform for intact N- and O-glycopeptide discovery and analysis

(2015) Christina M Woo et al.   NATURE METHODS

Chemically tunable mucin chimeras assembled on living cells

(2015) Jessica R. Kramer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane proximal ectodomain cleavage of MUC16 occurs in the acidifying Golgi/post-Golgi compartments

(2015) Srustidhar Das et al.   Scientific Reports

Synthesis of a Glycopeptide Vaccine Conjugate for Induction of Antibodies Recognizing O-Mannosyl Glycopeptides

(2014) Jin Yu et al.   CHEMBIOCHEM

CD43 Regulates Th2 Differentiation and Inflammation

(2014) J. L. Cannon et al.   JOURNAL OF IMMUNOLOGY

Site-specific analysis of the O-glycosylation of bovine fetuin by electron-transfer dissociation mass spectrometry

(2014) Markus Windwarder et al.   Journal of Proteomics

MUC16 (CA125): tumor biomarker to cancer therapy, a work in progress

(2014) Mildred Felder et al.   Molecular Cancer

Structural basis for simultaneous recognition of an O-glycan and its attached peptide of mucin family by immune receptor PILR 

(2014) K. Kuroki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced Mass Spectrometric Mapping of the Human GalNAc-typeO-Glycoproteome with SimpleCells

(2013) Sergey Y. Vakhrushev et al.   MOLECULAR & CELLULAR PROTEOMICS

Total cellular glycomics allows characterizing cells and streamlining the discovery process for cellular biomarkers

(2013) N. Fujitani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Architecture and function of metallopeptidase catalytic domains

(2013) Núria Cerdà-Costa et al.   PROTEIN SCIENCE

Multifarious roles of sialic acids in immunity

(2012) Ajit Varki et al.   Annals of the New York Academy of Sciences

MUC1 Vaccine for Individuals with Advanced Adenoma of the Colon: A Cancer Immunoprevention Feasibility Study

(2012) T. Kimura et al.   Cancer Prevention Research

O-Linked glycome and proteome of high-molecular-mass proteins in human ovarian cancer ascites: Identification of sulfation, disialic acid and O-linked fucose

(2012) Niclas G Karlsson et al.   GLYCOBIOLOGY

A Novel Extracellular Metallopeptidase Domain Shared by Animal Host-Associated Mutualistic and Pathogenic Microbes

(2012) Sirintra Nakjang et al.   PLoS One

Structural Insight into the Bacterial Mucinase StcE Essential to Adhesion and Immune Evasion during Enterohemorrhagic E. coli Infection

(2012) Angel C.Y. Yu et al.   STRUCTURE

Mucin 1 C-Terminal Subunit Oncoprotein Is a Target for Small-Molecule Inhibitors

(2011) Y. Zhou et al.   MOLECULAR PHARMACOLOGY

Ovarian cancer biomarkers for molecular biosensors and translational medicine

(2010) K Stephen Suh et al.   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

T Cell Ig and Mucin Domain Proteins and Immunity

(2010) L. P. Kane   JOURNAL OF IMMUNOLOGY

Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes

(2010) Jennifer A. Belisle et al.   Molecular Cancer

Quantitative site-specific analysis of protein glycosylation by LC-MS using different glycopeptide-enrichment strategies

(2009) Jessica Wohlgemuth et al.   ANALYTICAL BIOCHEMISTRY

The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers

(2009) Nicolas Jonckheere et al.   BIOCHIMIE

Glycomics Profiling of Chinese Hamster Ovary Cell Glycosylation Mutants RevealsN-Glycans of a Novel Size and Complexity

(2009) Simon J. North et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High-efficiency labeling of sialylated glycoproteins on living cells

(2009) Ying Zeng et al.   NATURE METHODS

Expression of podocalyxin enhances the adherence, migration, and intercellular communication of cells

(2008) Susana Larrucea et al.   EXPERIMENTAL CELL RESEARCH