Canonical Wnt is inhibited by targeting one-carbon metabolism through methotrexate or methionine deprivation

APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway

(2018) Kenyi Saito-Diaz et al.   DEVELOPMENTAL CELL

Arginine methylation of Smad7 by PRMT1 in TGF-β-induced epithelial-mesenchymal transition and epithelial stem cell generation

(2018) Yoko Katsuno et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arginine methylation is required for canonical Wnt signaling and endolysosomal trafficking

(2018) Lauren V. Albrecht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Abstract 4658: Novel paclitaxel medical nanoparticle formulation for breast cancer

(2018) Pallabita Chowdhury et al.   CANCER RESEARCH

Histidine catabolism is a major determinant of methotrexate sensitivity

(2018) Naama Kanarek et al.   NATURE

Bighead is a Wnt antagonist secreted by the Xenopus Spemann organizer that promotes Lrp6 endocytosis

(2018) Yi Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arginine Methylation: The Coming of Age

(2017) Roméo S. Blanc et al.   MOLECULAR CELL

A Metabolic Function for Phospholipid and Histone Methylation

(2017) Cunqi Ye et al.   MOLECULAR CELL

Nutrient acquisition strategies of mammalian cells

(2017) Wilhelm Palm et al.   NATURE

Lysosomal metabolomics reveals V-ATPase- and mTOR-dependent regulation of amino acid efflux from lysosomes

(2017) Monther Abu-Remaileh et al.   SCIENCE

SAMTOR is anS-adenosylmethionine sensor for the mTORC1 pathway

(2017) Xin Gu et al.   SCIENCE

Metabolic control of methylation and acetylation

(2016) Xiaoyang Su et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The importance of serine metabolism in cancer

(2016) Katherine R. Mattaini et al.   JOURNAL OF CELL BIOLOGY

Folate deficiency affects histone methylation

(2016) Benjamin A. Garcia et al.   MEDICAL HYPOTHESES

Mechanism of arginine sensing by CASTOR1 upstream of mTORC1

(2016) Robert A. Saxton et al.   NATURE

Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors

(2016) Shawn M Davidson et al.   NATURE MEDICINE

Preventing and Managing Toxicities of High-Dose Methotrexate

(2016) S. C. Howard et al.   ONCOLOGIST

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

(2016) Konstantinos J. Mavrakis et al.   SCIENCE

Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

(2016) Sara C. Larsen et al.   Science Signaling

Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells

(2016) Sara C. Larsen et al.   Science Signaling

Fundamentals of cancer metabolism

(2016) R. J. DeBerardinis et al.   Science Advances

Post-transcriptional Wnt Signaling Governs Epididymal Sperm Maturation

(2015) Stefan Koch et al.   CELL

Histone Methylation Dynamics and Gene Regulation Occur through the Sensing of One-Carbon Metabolism

(2015) Samantha J. Mentch et al.   Cell Metabolism

MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells

(2015) Diego Ploper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1

(2015) S. Wang et al.   SCIENCE

Wnt Signaling Translocates Lys48-Linked Polyubiquitinated Proteins to the Lysosomal Pathway

(2015) Hyunjoon Kim et al.   Cell Reports

Spina bifida

(2015) Andrew J. Copp et al.   Nature Reviews Disease Primers

Quantitation of Cellular Metabolic Fluxes of Methionine

(2014) Tomer Shlomi et al.   ANALYTICAL CHEMISTRY

Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer

(2014) K. T. Pate et al.   EMBO JOURNAL

The quantified cell

(2014) Avi Flamholz et al.   MOLECULAR BIOLOGY OF THE CELL

Multivesicular GSK3 Sequestration upon Wnt Signaling Is Controlled by p120-Catenin/Cadherin Interaction with LRP5/6

(2014) Meritxell Vinyoles et al.   MOLECULAR CELL

Mitotic Wnt Signaling Promotes Protein Stabilization and Regulates Cell Size

(2014) Sergio P. Acebron et al.   MOLECULAR CELL

Methionine Inhibits Autophagy and Promotes Growth by Inducing the SAM-Responsive Methylation of PP2A

(2013) Benjamin M. Sutter et al.   CELL

WNT-LRP5 Signaling Induces Warburg Effect through mTORC2 Activation during Osteoblast Differentiation

(2013) Emel Esen et al.   Cell Metabolism

Nutritional Control of Epigenetic Processes in Yeast and Human Cells

(2013) Meru J. Sadhu et al.   GENETICS

Arginine Methylation Initiates BMP-Induced Smad Signaling

(2013) Jian Xu et al.   MOLECULAR CELL

Defining the RGG/RG Motif

(2013) Palaniraja Thandapani et al.   MOLECULAR CELL

Cancer mistunes methylation

(2013) Tomer Shlomi et al.   Nature Chemical Biology

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

(2013) Olesya A Ulanovskaya et al.   Nature Chemical Biology

Thyroid Hormone Activates Protein Arginine Methyltransferase 1 Expression by Directly Inducing c-Myc Transcription during Xenopus Intestinal Stem Cell Development

(2012) Kenta Fujimoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-adenosylmethionine in Liver Health, Injury, and Cancer

(2012) Shelly C. Lu et al.   PHYSIOLOGICAL REVIEWS

Influence of Threonine Metabolism on S-Adenosylmethionine and Histone Methylation

(2012) N. Shyh-Chang et al.   SCIENCE

Regulation of protein stability by GSK3 mediated phosphorylation

(2011) Chong Xu et al.   CELL CYCLE

Endocytic Trafficking and Wnt/β-Catenin Signaling

(2011) Oscar Pellon-Cardenas et al.   CURRENT DRUG TARGETS

Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis

(2011) J. Y. Guo et al.   GENES & DEVELOPMENT

GSK-3: Functional Insights from Cell Biology and Animal Models

(2011) Oksana Kaidanovich-Beilin et al.   Frontiers in Molecular Neuroscience

Wnt Signaling: Multivesicular Bodies Hold GSK3 Captive

(2010) Christof Niehrs et al.   CELL

Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

(2010) Vincent F. Taelman et al.   CELL

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

An Essential and Evolutionarily Conserved Role of Protein Arginine Methyltransferase 1 for Adult Intestinal Stem Cells During Postembryonic Development

(2010) Hiroki Matsuda et al.   STEM CELLS

Cell Cycle Control of Wnt Receptor Activation

(2009) Gary Davidson et al.   DEVELOPMENTAL CELL

Rab7 Regulates Late Endocytic Trafficking Downstream of Multivesicular Body Biogenesis and Cargo Sequestration

(2009) Phillip A. Vanlandingham et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mouse PRMT1 Null Allele Defines an Essential Role for Arginine Methylation in Genome Maintenance and Cell Proliferation

(2009) Z. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Protein Arginine Methylation in Mammals: Who, What, and Why

(2009) Mark T. Bedford et al.   MOLECULAR CELL

The PRMT1 gene expression pattern in colon cancer

(2008) K Mathioudaki et al.   BRITISH JOURNAL OF CANCER

Novel Functions of Protein Arginine Methyltransferase 1 in Thyroid Hormone Receptor-Mediated Transcription and in the Regulation of Metamorphic Rate in Xenopus laevis

(2008) H. Matsuda et al.   MOLECULAR AND CELLULAR BIOLOGY

Direct Inhibition of GSK3β by the Phosphorylated Cytoplasmic Domain of LRP6 in Wnt/β-Catenin Signaling

(2008) Shunfu Piao et al.   PLoS One