Cancer mistunes methylation

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

(2013) Olesya A Ulanovskaya et al.   Nature Chemical Biology

Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

(2011) Wei Xu et al.   CANCER CELL

The important role of glycine N-methyltransferase in the carcinogenesis and progression of prostate cancer

(2011) Yoo Hyun Song et al.   MODERN PATHOLOGY

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

(2009) Lenny Dang et al.   NATURE

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

(2009) Arun Sreekumar et al.   NATURE