Toll-Like Receptor-Mediated Recognition of Nucleic Acid Nanoparticles (NANPs) in Human Primary Blood Cells

Targeting the mTOR Signaling Pathway Utilizing Nanoparticles: A Critical Overview

(2019) Mariia Lunova et al.   Cancers

Dynamic Behavior of RNA Nanoparticles Analyzed by AFM on a Mica/Air Interface

(2018) Sameer Sajja et al.   LANGMUIR

Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles

(2018) Enping Hong et al.   NANO LETTERS

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition

(2018) Lauren Rackley et al.   ADVANCED FUNCTIONAL MATERIALS

Roadmap and strategy for overcoming infusion reactions to nanomedicines

(2018) Janos Szebeni et al.   Nature Nanotechnology

RNA–DNA fibers and polygons with controlled immunorecognition activate RNAi, FRET and transcriptional regulation of NF-κB in human cells

(2018) Weina Ke et al.   NUCLEIC ACIDS RESEARCH

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

Functionally-interdependent shape-switching nanoparticles with controllable properties

(2017) Justin R. Halman et al.   NUCLEIC ACIDS RESEARCH

Programmable Nucleic Acid Based Polygons with Controlled Neuroimmunomodulatory Properties for Predictive QSAR Modeling

(2017) Morgan Brittany Johnson et al.   Small

Development of Guanidinium-Rich Protein Mimics for Efficient siRNA Delivery into Human T Cells

(2015) Brittany M. deRonde et al.   BIOMACROMOLECULES

An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics

(2015) Daniel M. Reed et al.   FASEB JOURNAL

Pre-clinical immunotoxicity studies of nanotechnology-formulated drugs: Challenges, considerations and strategy

(2015) Marina A. Dobrovolskaia   JOURNAL OF CONTROLLED RELEASE

Cytokine release assays for the prediction of therapeutic mAb safety in first-in man trials — Whole blood cytokine release assays are poorly predictive for TGN1412 cytokine storm

(2015) S. Vessillier et al.   JOURNAL OF IMMUNOLOGICAL METHODS

In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACS Nano

Cytokine release assays: Current practices and future directions

(2014) D. Finco et al.   CYTOKINE

An efficient siRNA-mediated gene silencing in primary human monocytes, dendritic cells and macrophages

(2014) Anthony Troegeler et al.   IMMUNOLOGY AND CELL BIOLOGY

Multifunctional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   NANO LETTERS

A single-stranded architecture for cotranscriptional folding of RNA nanostructures

(2014) C. Geary et al.   SCIENCE

Stable RNA nanoparticles as potential new generation drugs for cancer therapy

(2013) Yi Shu et al.   ADVANCED DRUG DELIVERY REVIEWS

Computational and experimental characterization of RNA cubic nanoscaffolds

(2013) Kirill A. Afonin et al.   METHODS

Conference Scene: Advances in RNA nanotechnology promise to transform medicine

(2013) Neocles Leontis et al.   Nanomedicine

Activation of different split functionalities on re-association of RNA–DNA hybrids

(2013) Kirill A. Afonin et al.   Nature Nanotechnology

Fabrication of pRNA nanoparticles to deliver therapeutic RNAs and bioactive compounds into tumor cells

(2013) Yi Shu et al.   Nature Protocols

Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

(2013) Liang Feng et al.   PHARMACEUTICAL RESEARCH

Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

(2013) Y. Shu et al.   RNA

After TGN1412: Recent developments in cytokine release assays

(2012) R. Stebbings et al.   Journal of Immunotoxicology

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Making Sense of the Cytokine Storm: A Conceptual Framework for Understanding, Diagnosing, and Treating Hemophagocytic Syndromes

(2012) Scott W. Canna et al.   PEDIATRIC CLINICS OF NORTH AMERICA

Self-Assembling RNA Nanorings Based on RNAI/II Inverse Kissing Complexes

(2011) Wade W. Grabow et al.   NANO LETTERS

Synthetic RNA–protein complex shaped like an equilateral triangle

(2011) Hirohisa Ohno et al.   Nature Nanotechnology

Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine

(2011) Kirill A Afonin et al.   Nature Protocols

Self-assembling RNA square

(2011) S. M. Dibrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunostimulatory Potential of Silencing RNAs Can Be Mediated by a Non-Uridine-Rich Toll-Like Receptor 7 Motif

(2011) Marion Jurk et al.   Nucleic Acid Therapeutics

In vitro assembly of cubic RNA-based scaffolds designed in silico

(2010) Kirill A. Afonin et al.   Nature Nanotechnology

The emerging field of RNA nanotechnology

(2010) Peixuan Guo   Nature Nanotechnology

Synthetic biology with RNA motifs

(2008) Hirohide Saito et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY