RNA Fibers as Optimized Nanoscaffolds for siRNA Coordination and Reduced Immunological Recognition

Structure and Composition Define Immunorecognition of Nucleic Acid Nanoparticles

(2018) Enping Hong et al.   NANO LETTERS

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis

(2018) David Adams et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Oligonucleotide Safety Working Group (OSWG)

(2018) Dave Schubert et al.   Nucleic Acid Therapeutics

Mesoporous Silica Nanoparticles as Carriers for Intracellular Delivery of Nucleic Acids and Subsequent Therapeutic Applications

(2017) Wenzhang Cha et al.   MOLECULES

Composing RNA Nanostructures from a Syntax of RNA Structural Modules

(2017) Cody Geary et al.   NANO LETTERS

Versatile RNA tetra-U helix linking motif as a toolkit for nucleic acid nanotechnology

(2017) My N. Bui et al.   Nanomedicine-Nanotechnology Biology and Medicine

Targeting Therapeutic Oligonucleotides

(2017) Arthur A. Levin   NEW ENGLAND JOURNAL OF MEDICINE

Programmable Nucleic Acid Based Polygons with Controlled Neuroimmunomodulatory Properties for Predictive QSAR Modeling

(2017) Morgan Brittany Johnson et al.   Small

Protein-driven RNA nanostructured devices that function in vitro and control mammalian cell fate

(2017) Tomonori Shibata et al.   Nature Communications

Stimuli-Responsive Mesoporous Silica NPs as Non-viral Dual siRNA/Chemotherapy Carriers for Triple Negative Breast Cancer

(2017) Behrad Darvishi et al.   Molecular Therapy-Nucleic Acids

Role of Type I and II Interferons in Colorectal Cancer and Melanoma

(2017) Simone Di Franco et al.   Frontiers in Immunology

Applications of Discrete Molecular Dynamics in biology and medicine

(2016) Elizabeth A Proctor et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Mucin-1-Antibody-Conjugated Mesoporous Silica Nanoparticles for Selective Breast Cancer Detection in a Mucin-1 Transgenic Murine Mouse Model

(2016) Didier Dréau et al.   Journal of Biomedical Nanotechnology

Specific Delivery of MiRNA for High Efficient Inhibition of Prostate Cancer by RNA Nanotechnology

(2016) Daniel W Binzel et al.   MOLECULAR THERAPY

Programmable RNA microstructures for coordinated delivery of siRNAs

(2016) Jaimie Marie Stewart et al.   Nanoscale

From the RNA world to the clinic

(2016) B. A. Sullenger et al.   SCIENCE

Cellular endocytosis and trafficking of cholera toxin B-modified mesoporous silica nanoparticles

(2016) William A. Walker et al.   Journal of Materials Chemistry B

Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology

(2015) Dan Shu et al.   ACS Nano

Delivery of RNA Nanoparticles into Colorectal Cancer Metastases Following Systemic Administration

(2015) Piotr Rychahou et al.   ACS Nano

iFoldRNA v2: folding RNA with constraints: Fig. 1.

(2015) Andrey Krokhotin et al.   BIOINFORMATICS

Immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics

(2015) Marina A Dobrovolskaia et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Strategy for selecting nanotechnology carriers to overcome immunological and hematological toxicities challenging clinical translation of nucleic acid-based therapeutics

(2015) Marina A Dobrovolskaia et al.   Expert Opinion on Drug Delivery

Pre-clinical immunotoxicity studies of nanotechnology-formulated drugs: Challenges, considerations and strategy

(2015) Marina A. Dobrovolskaia   JOURNAL OF CONTROLLED RELEASE

RNA as a stable polymer to build controllable and defined nanostructures for material and biomedical applications

(2015) Hui Li et al.   Nano Today

Induction of oxidative stress by Taxol® vehicle Cremophor-EL triggers production of interleukin-8 by peripheral blood mononuclear cells through the mechanism not requiring de novo synthesis of mRNA

(2015) Anna N. Ilinskaya et al.   Nanomedicine-Nanotechnology Biology and Medicine

Oligo Safety Working Group Exaggerated Pharmacology Subcommittee Consensus Document

(2015) Doug Kornbrust et al.   Nucleic Acid Therapeutics

In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACCOUNTS OF CHEMICAL RESEARCH

RNA Self-Assembly and RNA Nanotechnology

(2014) Wade W. Grabow et al.   ACCOUNTS OF CHEMICAL RESEARCH

Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACS Nano

Multifunctional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   NANO LETTERS

A single-stranded architecture for cotranscriptional folding of RNA nanostructures

(2014) C. Geary et al.   SCIENCE

Emerging insights into resistance to BRAF inhibitors in melanoma

(2013) Amanda D. Bucheit et al.   BIOCHEMICAL PHARMACOLOGY

Activation of different split functionalities on re-association of RNA–DNA hybrids

(2013) Kirill A. Afonin et al.   Nature Nanotechnology

Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

(2013) Liang Feng et al.   PHARMACEUTICAL RESEARCH

Mesoporous Silica Nanoparticles: Synthesis, Biocompatibility and Drug Delivery

(2012) Fangqiong Tang et al.   ADVANCED MATERIALS

Multifunctional ZnPc-loaded mesoporous silica nanoparticles for enhancement of photodynamic therapy efficacy by endolysosomal escape

(2012) Jing Tu et al.   BIOMATERIALS

RNA-Based Therapeutics: Current Progress and Future Prospects

(2012) John C. Burnett et al.   CHEMISTRY & BIOLOGY

Discrete Molecular Dynamics: An Efficient And Versatile Simulation Method For Fine Protein Characterization

(2012) David Shirvanyants et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Co-transcriptional Assembly of Chemically Modified RNA Nanoparticles Functionalized with siRNAs

(2012) Kirill A. Afonin et al.   NANO LETTERS

Assessing unintended hybridization-induced biological effects of oligonucleotides

(2012) Morten Lindow et al.   NATURE BIOTECHNOLOGY

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Mutant BRAF Melanomas—Dependence and Resistance

(2011) Poulikos I. Poulikakos et al.   CANCER CELL

Structural and Thermodynamic Effects of Post-translational Modifications in Mutant and Wild Type Cu, Zn Superoxide Dismutase

(2011) Elizabeth A. Proctor et al.   JOURNAL OF MOLECULAR BIOLOGY

Self-Assembling RNA Nanorings Based on RNAI/II Inverse Kissing Complexes

(2011) Wade W. Grabow et al.   NANO LETTERS

Thermodynamically stable RNA three-way junction for constructing multifunctional nanoparticles for delivery of therapeutics

(2011) Dan Shu et al.   Nature Nanotechnology

Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine

(2011) Kirill A Afonin et al.   Nature Protocols

Engineered Design of Mesoporous Silica Nanoparticles to Deliver Doxorubicin and P-Glycoprotein siRNA to Overcome Drug Resistance in a Cancer Cell Line

(2010) Huan Meng et al.   ACS Nano

Long-term therapeutic efficacy and toxicity of recombinant interferon-alpha 2a in polycythaemia vera

(2010) P. Foa et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

In vitro assembly of cubic RNA-based scaffolds designed in silico

(2010) Kirill A. Afonin et al.   Nature Nanotechnology

The emerging field of RNA nanotechnology

(2010) Peixuan Guo   Nature Nanotechnology

Strategies in the design of nanoparticles for therapeutic applications

(2010) Robby A. Petros et al.   NATURE REVIEWS DRUG DISCOVERY

Polyethyleneimine Coating Enhances the Cellular Uptake of Mesoporous Silica Nanoparticles and Allows Safe Delivery of siRNA and DNA Constructs

(2009) Tian Xia et al.   ACS Nano

Silencing by small RNAs is linked to endosomal trafficking

(2009) Young Sik Lee et al.   NATURE CELL BIOLOGY

Mesoporous silica nanoparticles as controlled release drug delivery and gene transfection carriers☆

(2008) I SLOWING et al.   ADVANCED DRUG DELIVERY REVIEWS

Colorimetric Determination of Polyamidoamine Dendrimers and their Derivates using a Simple and Rapid Ninhydrin Assay

(2008) Zhenhua Xu et al.   ANALYTICAL LETTERS

Nucleic Acids as Therapeutic Agents

(2008) Luis Alvarez-Salas   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Ab initio RNA folding by discrete molecular dynamics: From structure prediction to folding mechanisms

(2008) F. Ding et al.   RNA

Ab Initio Folding of Proteins with All-Atom Discrete Molecular Dynamics

(2008) Feng Ding et al.   STRUCTURE