Programmable Nucleic Acid Based Polygons with Controlled Neuroimmunomodulatory Properties for Predictive QSAR Modeling

Versatile RNA tetra-U helix linking motif as a toolkit for nucleic acid nanotechnology

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Immortalization of primary microglia: a new platform to study HIV regulation in the central nervous system

(2016) Yoelvis Garcia-Mesa et al.   JOURNAL OF NEUROVIROLOGY

Role of neuroinflammation in neurodegenerative diseases (Review)

(2016) WEI-WEI CHEN et al.   Molecular Medicine Reports

Design of Potent and Controllable Anticoagulants Using DNA Aptamers and Nanostructures

(2016) Abhijit Rangnekar et al.   MOLECULES

Programmable RNA microstructures for coordinated delivery of siRNAs

(2016) Jaimie Marie Stewart et al.   Nanoscale

Generation of siRNA Nanosheets for Efficient RNA Interference

(2016) Hyejin Kim et al.   Scientific Reports

DNA Nanotechnology for Cancer Therapeutics

(2016) Vinit Kumar et al.   Theranostics

Systemic Delivery of Anti-miRNA for Suppression of Triple Negative Breast Cancer Utilizing RNA Nanotechnology

(2015) Dan Shu et al.   ACS Nano

Delivery of RNA Nanoparticles into Colorectal Cancer Metastases Following Systemic Administration

(2015) Piotr Rychahou et al.   ACS Nano

Pre-clinical immunotoxicity studies of nanotechnology-formulated drugs: Challenges, considerations and strategy

(2015) Marina A. Dobrovolskaia   JOURNAL OF CONTROLLED RELEASE

Bolaamphiphiles as carriers for siRNA delivery: From chemical syntheses to practical applications

(2015) Kshitij Gupta et al.   JOURNAL OF CONTROLLED RELEASE

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

In Silico Design and Enzymatic Synthesis of Functional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Physicochemically Tunable Polyfunctionalized RNA Square Architecture with Fluorogenic and Ribozymatic Properties

(2014) Daniel L. Jasinski et al.   ACS Nano

Layer-by-Layer Assembled Antisense DNA Microsponge Particles for Efficient Delivery of Cancer Therapeutics

(2014) Young Hoon Roh et al.   ACS Nano

Triggering of RNA Interference with RNA–RNA, RNA–DNA, and DNA–RNA Nanoparticles

(2014) Kirill A. Afonin et al.   ACS Nano

Neurogenic Exacerbation of Microglial and Astrocyte Responses to Neisseria meningitidis and Borrelia burgdorferi

(2014) V. S. Chauhan et al.   JOURNAL OF IMMUNOLOGY

Multifunctional RNA Nanoparticles

(2014) Kirill A. Afonin et al.   NANO LETTERS

Microglial priming in neurodegenerative disease

(2014) V. Hugh Perry et al.   Nature Reviews Neurology

Enhancing immunomodulation on innate immunity by shape transition among RNA triangle, square and pentagon nanovehicles

(2014) Emil F. Khisamutdinov et al.   NUCLEIC ACIDS RESEARCH

Sequence Design for a Test Tube of Interacting Nucleic Acid Strands

(2014) Brian R. Wolfe et al.   ACS Synthetic Biology

Delivery of analgesic peptides to the brain by nano-sized bolaamphiphilic vesicles made of monolayer membranes

(2013) Mary Popov et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Activation of different split functionalities on re-association of RNA–DNA hybrids

(2013) Kirill A. Afonin et al.   Nature Nanotechnology

Co-transcriptional production of RNA–DNA hybrids for simultaneous release of multiple split functionalities

(2013) Kirill A. Afonin et al.   NUCLEIC ACIDS RESEARCH

Ocular Delivery of pRNA Nanoparticles: Distribution and Clearance After Subconjunctival Injection

(2013) Liang Feng et al.   PHARMACEUTICAL RESEARCH

Fabrication of 14 different RNA nanoparticles for specific tumor targeting without accumulation in normal organs

(2013) Y. Shu et al.   RNA

In Silico, In Vitro, and In Vivo Studies Indicate the Potential Use of Bolaamphiphiles for Therapeutic siRNAs Delivery

(2013) Taejin Kim et al.   Molecular Therapy-Nucleic Acids

Computational tools and resources for metabolism-related property predictions. 2. Application to prediction of half-life time in human liver microsomes

(2012) Alexey V Zakharov et al.   Future Medicinal Chemistry

Revised AMBER Parameters for Bioorganic Phosphates

(2012) T. Steinbrecher et al.   Journal of Chemical Theory and Computation

Innate immunity in the central nervous system

(2012) Richard M. Ransohoff et al.   JOURNAL OF CLINICAL INVESTIGATION

Scientific workflow systems: Pipeline Pilot and KNIME

(2012) Wendy A. Warr   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

A DNA Nanostructure Platform for Directed Assembly of Synthetic Vaccines

(2012) Xiaowei Liu et al.   NANO LETTERS

Self-assembled RNA interference microsponges for efficient siRNA delivery

(2012) Jong Bum Lee et al.   NATURE MATERIALS

Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery

(2012) Hyukjin Lee et al.   Nature Nanotechnology

Cellular Immunostimulation by CpG-Sequence-Coated DNA Origami Structures

(2011) Verena J. Schüller et al.   ACS Nano

Site-directed decapsulation of bolaamphiphilic vesicles with enzymatic cleavable surface groups

(2011) Mary Popov et al.   JOURNAL OF CONTROLLED RELEASE

Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine

(2011) Kirill A Afonin et al.   Nature Protocols

Nucleic acid sequence design via efficient ensemble defect optimization

(2010) Joseph N. Zadeh et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

NUPACK: Analysis and design of nucleic acid systems

(2010) Joseph N. Zadeh et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Best Practices for QSAR Model Development, Validation, and Exploitation

(2010) Alexander Tropsha   Molecular Informatics

The emerging field of RNA nanotechnology

(2010) Peixuan Guo   Nature Nanotechnology