An autologous endothelial cell:peripheral blood mononuclear cell assay that detects cytokine storm responses to biologics

Morphology and vasoactive hormone profiles from endothelial cells derived from stem cells of different sources

(2014) Daniel M. Reed et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cytokine release assays: Current practices and future directions

(2014) D. Finco et al.   CYTOKINE

Pathogen Sensing Pathways in Human Embryonic Stem Cell Derived-Endothelial Cells: Role of NOD1 Receptors

(2014) Daniel M. Reed et al.   PLoS One

Cellular and molecular basis of von Willebrand disease: studies on blood outgrowth endothelial cells

(2013) R. D. Starke et al.   BLOOD

Severity of the TGN1412 trial disaster cytokine storm correlated with IL-2 release

(2013) David Eastwood et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

How predictive are in vitro assays for cytokine release syndrome in vivo? A comparison of methods reveals worrying differences in sensitivity and frequency of response

(2013) Susan J. Thorpe et al.   CYTOKINE

Dysfunction of Endothelial Progenitor Cells from Smokers and Chronic Obstructive Pulmonary Disease Patients Due to Increased DNA Damage and Senescence

(2013) Koralia E. Paschalaki et al.   STEM CELLS

Ofatumumab monotherapy in rituximab-refractory follicular lymphoma: results from a multicenter study

(2012) M. S. Czuczman et al.   BLOOD

A whole blood in vitro cytokine release assay with aqueous monoclonal antibody presentation for the prediction of therapeutic protein induced cytokine release syndrome in humans

(2012) Babette Wolf et al.   CYTOKINE

Antibody C Region Influences TGN1412-like Functional Activity In Vitro

(2012) C. Ball et al.   JOURNAL OF IMMUNOLOGY

Establishment of outgrowth endothelial cells from peripheral blood

(2012) Javier Martin-Ramirez et al.   Nature Protocols

A simple whole blood bioassay detects cytokine responses to anti-CD28 SA and anti-CD52 antibodies

(2012) Lucy Bailey et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Endothelial cells co-stimulate peripheral blood mononuclear cell responses to monoclonal antibody TGN1412 in culture

(2011) Lucy Findlay et al.   CYTOKINE

Comparison of novel methods for predicting the risk of pro-inflammatory clinical infusion reactions during monoclonal antibody therapy

(2011) Lucy Findlay et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Endothelial von Willebrand factor regulates angiogenesis

(2010) R. D. Starke et al.   BLOOD

Improved in vitro methods to predict the in vivo toxicity in man of therapeutic monoclonal antibodies including TGN1412

(2009) Lucy Findlay et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Managing Premedications and the Risk for Reactions to Infusional Monoclonal Antibody Therapy

(2008) C. H. Chung   ONCOLOGIST

Signaling Signatures and Functional Properties of Anti-Human CD28 Superagonistic Antibodies

(2008) Zoe Waibler et al.   PLoS One