The Cholesterol-Modulating Effect of Methanol Extract of Pigeon Pea (Cajanus cajan (L.) Millsp.) Leaves on Regulating LDLR and PCSK9 Expression in HepG2 Cells

Pinostrobin Inhibits Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) Gene Expression through the Modulation of FoxO3a Protein in HepG2 Cells

(2018) Wan-Yun Gao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Stable liver-specific expression of human IDOL in humanized mice raises plasma cholesterol

(2016) Salam Ibrahim et al.   CARDIOVASCULAR RESEARCH

Therapeutic efficacy of PCSK9 monoclonal antibodies in statin-nonresponsive patients with hypercholesterolemia and dyslipidemia: A systematic review and meta-analysis

(2016) Wan Peng et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Anti-Inflammatory Effects of Cajaninstilbene Acid and Its Derivatives

(2016) Mei-Yan Huang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A review of low-density lipoprotein cholesterol, treatment strategies, and its impact on cardiovascular disease morbidity and mortality

(2016) Rishi K. Wadhera et al.   Journal of Clinical Lipidology

Targeting PCSK9 as a promising new mechanism for lowering low-density lipoprotein cholesterol

(2016) Laura A. Della Badia et al.   PHARMACOLOGY & THERAPEUTICS

Tanshinone IIA Modulates Low Density Lipoprotein Uptake via Down-Regulation of PCSK9 Gene Expression in HepG2 Cells

(2016) Hung-Chen Chen et al.   PLoS One

Kaempferol stimulates gene expression of low-density lipoprotein receptor through activation of Sp1 in cultured hepatocytes

(2016) Ayasa Ochiai et al.   Scientific Reports

Non-statin Treatments for Managing LDL Cholesterol and Their Outcomes

(2015) Traci Turner et al.   CLINICAL THERAPEUTICS

Activity of the antiestrogenic cajanin stilbene acid towards breast cancer

(2015) Yujie Fu et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Cell cycle arrest and induction of apoptosis by cajanin stilbene acid from Cajanus cajan in breast cancer cells

(2015) Yujie Fu et al.   PHYTOMEDICINE

The flavonoid profile of pigeonpea, Cajanus cajan: a review

(2015) Aaron Nix et al.   SpringerPlus

Cajaninstilbene Acid Prevents Corticosterone-Induced Apoptosis in PC12 Cells by Inhibiting the Mitochondrial Apoptotic Pathway

(2014) Bao-Ping Jiang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

PCSK9 and LDLR degradation

(2014) Thomas A. Lagace   CURRENT OPINION IN LIPIDOLOGY

Curcumin enhances cell-surface LDLR level and promotes LDL uptake through downregulation of PCSK9 gene expression in HepG2 cells

(2014) Mi-Hsueh Tai et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Potential of Proprotein Convertase Subtilisin/Kexin Type 9 Based Therapeutics

(2013) Evan A. Stein et al.   Current Atherosclerosis Reports

Effect of pigeon pea (Cajanus cajan L.) on high-fat diet-induced hypercholesterolemia in hamsters

(2013) Fan-Jhen Dai et al.   FOOD AND CHEMICAL TOXICOLOGY

Variation in Contents of Main Active Components and Antioxidant Activity in Leaves of Different Pigeon Pea Cultivars during Growth

(2013) Zuo-Fu Wei et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Post-transcriptional regulation of lipoprotein receptors by the E3-ubiquitin ligase inducible degrader of the low-density lipoprotein receptor

(2012) Vincenzo Sorrentino et al.   CURRENT OPINION IN LIPIDOLOGY

Citrus Flavanones: What Is Their Role in Cardiovascular Protection?

(2012) Audrey Chanet et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary curcumin inhibits atherosclerosis by affecting the expression of genes involved in leukocyte adhesion and transendothelial migration

(2012) Dilek Coban et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Antioxidant and anti-inflammatory effects of pigeon pea (Cajanus cajan L.) extracts on hydrogen peroxide- and lipopolysaccharide-treated RAW264.7 macrophages

(2012) Yi-Syuan Lai et al.   Food & Function

Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management

(2011) M. John Chapman et al.   EUROPEAN HEART JOURNAL

Determination and quantification of active phenolic compounds in pigeon pea leaves and its medicinal product using liquid chromatography–tandem mass spectrometry

(2010) Wei Liu et al.   JOURNAL OF CHROMATOGRAPHY A

Flavonoids: Antioxidants Against Atherosclerosis

(2010) Davide Grassi et al.   Nutrients

Cellular and secreted pro-protein convertase subtilisin/kexin type 9 catalytic activity in hepatocytes

(2009) Sanae Kourimate et al.   ATHEROSCLEROSIS

Hepatocyte Nuclear Factor 1α Plays a Critical Role inPCSK9Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine

(2009) Hai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation

(2009) Steve Poirier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidant Activities of Extracts and Main Components of Pigeonpea [Cajanus cajan (L.) Millsp.] Leaves

(2009) Nan Wu et al.   MOLECULES

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

Berberine decreases PCSK9 expression in HepG2 cells

(2008) Jamie Cameron et al.   ATHEROSCLEROSIS

Molecular basis of PCSK9 function

(2008) Gilles Lambert et al.   ATHEROSCLEROSIS

Hypocholesterolemic effect of stilbenes containing extract-fraction from Cajanus cajan L. on diet-induced hypercholesterolemia in mice

(2008) Qing-Feng Luo et al.   PHYTOMEDICINE

PCSK9 and LDL cholesterol: unravelling the target to design the bullet

(2008) Philippe Costet et al.   TRENDS IN BIOCHEMICAL SCIENCES