Curcumin enhances cell-surface LDLR level and promotes LDL uptake through downregulation of PCSK9 gene expression in HepG2 cells

Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice

(2013) S.T. Hasan et al.   ATHEROSCLEROSIS

Comparison of the effects of curcumin and curcumin glucuronide in human hepatocellular carcinoma HepG2 cells

(2013) Motomu Shoji et al.   FOOD CHEMISTRY

Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction

(2013) Min Zheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Curcuminoids distinctly exhibit antioxidant activities and regulate expression of scavenger receptors and heme oxygenase-1

(2013) Mei-Chun Kou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Down-Regulation of the Oncogene PTTG1 via the KLF6 Tumor Suppressor during Induction of Myeloid Differentiation

(2013) Pei-Yi Chen et al.   PLoS One

Delineation of molecular pathways that regulate hepatic PCSK9 and LDL receptor expression during fasting in normolipidemic hamsters

(2012) Minhao Wu et al.   ATHEROSCLEROSIS

PCSK9 Inhibition

(2012) Robert A. Vogel   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Clinical aspects of PCSK9

(2011) Bertrand Cariou et al.   ATHEROSCLEROSIS

Unexpected roles for PCSK9 in lipid metabolism

(2011) Anne K Soutar   CURRENT OPINION IN LIPIDOLOGY

Regulatory effects of curcumin on lipid accumulation in monocytes/macrophages

(2011) Jean-Marc Zingg et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Citrus flavonoid 5-demethylnobiletin suppresses scavenger receptor expression in THP-1 cells and alters lipid homeostasis in HepG2 liver cells

(2011) Jui-Hung Yen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin: An Anti-Inflammatory Molecule from a Curry Spice on the Path to Cancer Treatment

(2011) Purusotam Basnet et al.   MOLECULES

Beyond LDL Cholesterol, a New Role for PCSK9

(2010) Omar N. Akram et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Huh-7 or HepG2 cells: which is the better model for studying human apolipoprotein-B100 assembly and secretion?

(2010) Steven J. R. Meex et al.   JOURNAL OF LIPID RESEARCH

Strong induction of PCSK9 gene expression through HNF1α and SREBP2: mechanism for the resistance to LDL-cholesterol lowering effect of statins in dyslipidemic hamsters

(2010) Bin Dong et al.   JOURNAL OF LIPID RESEARCH

High-dose atorvastatin causes a rapid sustained increase in human serum PCSK9 and disrupts its correlation with LDL cholesterol

(2010) Greg Welder et al.   JOURNAL OF LIPID RESEARCH

Coffee, broccoli and spices are strong inducers of electrophile response element-dependent transcription in vitro and in vivo - Studies in electrophile response element transgenic mice

(2010) Trude Rakel Balstad et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected From Postprandial Triglyceridemia

(2009) Cédric Le May et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The LDL Receptor

(2009) Joseph L. Goldstein et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Curcumin suppresses expression of low-density lipoprotein (LDL) receptor, leading to the inhibition of LDL-induced activation of hepatic stellate cells

(2009) Qiaohua Kang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Curcumin Inhibitssrebp-2Expression in Activated Hepatic Stellate Cellsin Vitroby Reducing the Activity of Specificity Protein-1

(2009) Qiaohua Kang et al.   ENDOCRINOLOGY

Specific Expression and Regulation of Hepassocin in the Liver and Down-regulation of the Correlation of HNF1α with Decreased Levels of Hepassocin in Human Hepatocellular Carcinoma

(2009) Hai-Tao Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatocyte Nuclear Factor 1α Plays a Critical Role inPCSK9Gene Transcription and Regulation by the Natural Hypocholesterolemic Compound Berberine

(2009) Hai Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LXR Regulates Cholesterol Uptake Through Idol-Dependent Ubiquitination of the LDL Receptor

(2009) Noam Zelcer et al.   SCIENCE

Berberine decreases PCSK9 expression in HepG2 cells

(2008) Jamie Cameron et al.   ATHEROSCLEROSIS

Involvement of anti-inflammatory heme oxygenase-1 in the inhibitory effect of curcumin on the expression of pro-inflammatory inducible nitric oxide synthase in RAW264.7 macrophages

(2008) Ki Mo Kim et al.   BIOMEDICINE & PHARMACOTHERAPY

Pharmacokinetics of Curcumin Conjugate Metabolites in Healthy Human Subjects

(2008) S. K. Vareed et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Proprotein convertase subtilisin/kexin type 9 (PCSK9): Hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration

(2008) Ahmed Zaid et al.   HEPATOLOGY

Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabeticdb/dbmice

(2008) Kwon-Il Seo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Curcumin Up-Regulates LDL Receptor Expression via the Sterol Regulatory Element Pathway in HepG2 Cells

(2008) Xiaobing Dou et al.   PLANTA MEDICA