Role of cholesterol and sphingolipids in brain development and neurological diseases

N-methyl-D-aspartate receptor–mediated calcium influx connects amyloid-β oligomers to ectopic neuronal cell cycle reentry in Alzheimer's disease

(2018) Erin J. Kodis et al.   Alzheimers & Dementia

DYSREGULATION OF INTRACELLULAR CALCIUM SIGNALING IN ALZHEIMER’S DISEASE

(2018) Elena Popugaeva et al.   ANTIOXIDANTS & REDOX SIGNALING

The role of glucocerebrosidase in Parkinson disease pathogenesis

(2018) Matthew E. Gegg et al.   FEBS Journal

Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function

(2018) Myung Jong Kim et al.   HUMAN MOLECULAR GENETICS

Different Associations of Plasma Biomarkers in Alzheimer's Disease, Mild Cognitive Impairment, Vascular Dementia, and Ischemic Stroke

(2018) Jingwei Shang et al.   Journal of Clinical Neurology

“Force-from-lipids” gating of mechanosensitive channels modulated by PUFAs

(2018) Pietro Ridone et al.   Journal of the Mechanical Behavior of Biomedical Materials

Role of Plant-Derived Flavonoids and Their Mechanism in Attenuation of Alzheimer’s and Parkinson’s Diseases: An Update of Recent Data

(2018) Ghulam Hussain et al.   MOLECULES

APOEε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults

(2018) Shahram Oveisgharan et al.   NEUROLOGY

Accumulation of Cholesterol and Homocysteine in the Nigrostriatal Pathway of Brain Contributes to the Dopaminergic Neurodegeneration in Mice

(2018) Rajib Paul et al.   NEUROSCIENCE

Inhibition of sphingomyelin synthase 1 ameliorates alzheimer-like pathology in APP/PS1 transgenic mice through promoting lysosomal degradation of BACE1

(2018) Mei-Hong Lu et al.   EXPERIMENTAL NEUROLOGY

Early and brain region-specific decrease of de novo cholesterol biosynthesis in Huntington's disease: A cross-validation study in Q175 knock-in mice

(2017) Mahalakshmi Shankaran et al.   NEUROBIOLOGY OF DISEASE

Dietary and Endogenous Sphingolipid Metabolism in Chronic Inflammation

(2017) et al.   Nutrients

Sphingolipids: membrane microdomains in brain development, function and neurological diseases

(2017) Anne S. B. Olsen et al.   Open Biology

Schizophrenia-like phenotypes in mice with NMDA receptor ablation in intralaminar thalamic nucleus cells and gene therapy-based reversal in adults

(2017) K Yasuda et al.   Translational Psychiatry

Determining the Composition of Active Cholesterol in the Plasma Membrane of Single Cells by using Electrochemiluminescence

(2017) Huanzhen Zuo et al.   ChemElectroChem

The role of sphingolipids in neuronal plasticity of the brain

(2016) Sandro Sonnino et al.   JOURNAL OF NEUROCHEMISTRY

Potential health benefits of sphingolipids in milk and dairy products

(2016) Slavica Potočki et al.   Mljekarstvo

Exosomes in Alzheimer's disease

(2016) Tarja Malm et al.   NEUROCHEMISTRY INTERNATIONAL

Potential health benefits of sphingolipids in milk and dairy products

(2016) Slavica Potočki et al.   Mljekarstvo

From Molecules to the Clinic: Linking Schizophrenia and Metabolic Syndrome through Sphingolipids Metabolism

(2016) Rolando I. Castillo et al.   Frontiers in Neuroscience

Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS development

(2015) David Cunningham et al.   HUMAN MOLECULAR GENETICS

Incidental diagnosis of an asymptomatic adult-onset Alexander disease by brain magnetic resonance imaging for preoperative evaluation

(2015) Atsuhiko Sugiyama et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Neuroimaging in autism spectrum disorder: brain structure and function across the lifespan

(2015) Christine Ecker et al.   LANCET NEUROLOGY

Myelin Lipids Inhibit Axon Regeneration Following Spinal Cord Injury: a Novel Perspective for Therapy

(2015) Fernando M. Mar et al.   MOLECULAR NEUROBIOLOGY

Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation

(2015) Céline Galvagnion et al.   Nature Chemical Biology

Cholesterol metabolism and homeostasis in the brain

(2015) Juan Zhang et al.   Protein & Cell

Different oxysterols have opposing actions at N-methyl-d-aspartate receptors

(2014) Andrew J. Linsenbardt et al.   NEUROPHARMACOLOGY

Fingolimod for the treatment of neurological diseases—state of play and future perspectives

(2014) Robert Brunkhorst et al.   Frontiers in Cellular Neuroscience

A plural role for lipids in motor neuron diseases: energy, signaling and structure

(2014) Florent Schmitt et al.   Frontiers in Cellular Neuroscience

Lipid dynamics at dendritic spines

(2014) Carlos Gerardo Dotti et al.   Frontiers in Neuroanatomy

The complexity of sphingolipid biosynthesis in the endoplasmic reticulum

(2013) Rotem Tidhar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Analysis of the protein network of cholesterol homeostasis in different brain regions: An age and sex dependent perspective

(2013) Marco Segatto et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The link between altered cholesterol metabolism and Alzheimer's disease

(2012) Paola Gamba et al.   Annals of the New York Academy of Sciences

Ablation of Neuronal Ceramide Synthase 1 in Mice Decreases Ganglioside Levels and Expression of Myelin-associated Glycoprotein in Oligodendrocytes

(2012) Christina Ginkel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cognitive enhancement by omega-3 fatty acids from child-hood to old age: Findings from animal and clinical studies

(2012) Dirk W. Luchtman et al.   NEUROPHARMACOLOGY

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

(2011) M Carlén et al.   MOLECULAR PSYCHIATRY

Cholesterol: A Novel Regulatory Role in Myelin Formation

(2011) Gesine Saher et al.   NEUROSCIENTIST

Regulation of synaptic strength by sphingosine 1-phosphate in the hippocampus

(2010) T. Kanno et al.   NEUROSCIENCE

Lipids in Ca2+ signalling—An introduction

(2009) Roger C. Hardie et al.   CELL CALCIUM

Tumor necrosis factor-α-induced neutral sphingomyelinase-2 modulates synaptic plasticity by controlling the membrane insertion of NMDA receptors

(2009) David Wheeler et al.   JOURNAL OF NEUROCHEMISTRY

Sphingosine Facilitates SNARE Complex Assembly and Activates Synaptic Vesicle Exocytosis

(2009) Frédéric Darios et al.   NEURON

Roles of l-serine and sphingolipid synthesis in brain development and neuronal survival

(2008) Yoshio Hirabayashi et al.   PROGRESS IN LIPID RESEARCH