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Title
MAPT mutations, tauopathy, and mechanisms of neurodegeneration
Authors
Keywords
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Journal
LABORATORY INVESTIGATION
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2019-02-11
DOI
10.1038/s41374-019-0197-x
References
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Note: Only part of the references are listed.- Prion-like Spreading in Tauopathies
- (2018) Jacob I. Ayers et al. BIOLOGICAL PSYCHIATRY
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain
- (2018) Sarah L. DeVos et al. Frontiers in Neuroscience
- Clinical, Neuropathological, and Biochemical Characterization of the Novel Tau Mutation P332S
- (2018) Vincent Deramecourt et al. JOURNAL OF ALZHEIMERS DISEASE
- Structures of filaments from Pick’s disease reveal a novel tau protein fold
- (2018) Benjamin Falcon et al. NATURE
- Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies
- (2017) Kevin H. Strang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- GFP-Mutant Human Tau Transgenic Mice Develop Tauopathy Following CNS Injections of Alzheimer's Brain-Derived Pathological Tau or Synthetic Mutant Human Tau Fibrils
- (2017) Garrett S. Gibbons et al. JOURNAL OF NEUROSCIENCE
- Pathological Tau Strains from Human Brains Recapitulate the Diversity of Tauopathies in Nontransgenic Mouse Brain
- (2017) Sneha Narasimhan et al. JOURNAL OF NEUROSCIENCE
- Cryo-EM structures of tau filaments from Alzheimer’s disease
- (2017) Anthony W. P. Fitzpatrick et al. NATURE
- Identification of the Tau phosphorylation pattern that drives its aggregation
- (2017) Clément Despres et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of tau prion seeding activity and strains from formaldehyde-fixed tissue
- (2017) Sarah K. Kaufman et al. Acta Neuropathologica Communications
- Widespread tau seeding activity at early Braak stages
- (2016) Jennifer L. Furman et al. ACTA NEUROPATHOLOGICA
- Heterotypic seeding of Tau fibrillization by pre-aggregated Abeta provides potent seeds for prion-like seeding and propagation of Tau-pathology in vivo
- (2016) Bruno Vasconcelos et al. ACTA NEUROPATHOLOGICA
- High–Molecular-Weight Paired Helical Filaments from Alzheimer Brain Induces Seeding of Wild-Type Mouse Tau into an Argyrophilic 4R Tau Pathology in Vivo
- (2016) Emilie Audouard et al. AMERICAN JOURNAL OF PATHOLOGY
- Like prions: the propagation of aggregated tau and α-synuclein in neurodegeneration
- (2016) Michel Goedert et al. BRAIN
- FTDP-17 with Pick body-like inclusions associated with a novel tau mutation, p.E372G
- (2016) Pawel Tacik et al. BRAIN PATHOLOGY
- Tau and tauopathies
- (2016) Thomas Arendt et al. BRAIN RESEARCH BULLETIN
- Co-immunoprecipitation with Tau Isoform-specific Antibodies Reveals Distinct Protein Interactions and Highlights a Putative Role for 2N Tau in Disease
- (2016) Chang Liu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Short Fibrils Constitute the Major Species of Seed-Competent Tau in the Brains of Mice Transgenic for Human P301S Tau
- (2016) S. J. Jackson et al. JOURNAL OF NEUROSCIENCE
- Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice
- (2016) Julia Gerson et al. JOURNAL OF NEUROTRAUMA
- Primary Fibril Nucleation of Aggregation Prone Tau Fragments PHF6 and PHF6*
- (2016) Florent X. Smit et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Tau Prion Strains Dictate Patterns of Cell Pathology, Progression Rate, and Regional Vulnerability In Vivo
- (2016) Sarah K. Kaufman et al. NEURON
- Tau prions from Alzheimer’s disease and chronic traumatic encephalopathy patients propagate in cultured cells
- (2016) Amanda L. Woerman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau Structures
- (2016) Jesus Avila et al. Frontiers in Aging Neuroscience
- Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability
- (2016) M. Catarina Silva et al. Stem Cell Reports
- Using Human iPSC-Derived Neurons to Model TAU Aggregation
- (2016) An Verheyen et al. PLoS One
- Inefficient induction and spread of seeded tau pathology in P301L mouse model of tauopathy suggests inherent physiological barriers to transmission
- (2015) Paramita Chakrabarty et al. ACTA NEUROPATHOLOGICA
- A novel tau mutation, p.K317N, causes globular glial tauopathy
- (2015) Pawel Tacik et al. ACTA NEUROPATHOLOGICA
- Tau pathology spread in PS19 tau transgenic mice following locus coeruleus (LC) injections of synthetic tau fibrils is determined by the LC’s afferent and efferent connections
- (2015) Michiyo Iba et al. ACTA NEUROPATHOLOGICA
- Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
- (2015) Ilie-Cosmin Stancu et al. ACTA NEUROPATHOLOGICA
- RNA Binds to Tau Fibrils and Sustains Template-Assisted Growth
- (2015) Paul D. Dinkel et al. BIOCHEMISTRY
- Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation
- (2015) Hilda Mirbaha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Tau Mutation in Exon 12, p.Q336H, Causes Hereditary Pick Disease
- (2015) Pawel Tacik et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Tau Assembly: The Dominant Role of PHF6 (VQIVYK) in Microtubule Binding Region Repeat R3
- (2015) Pritam Ganguly et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Regulation of human MAPT gene expression
- (2015) Marie-Laure Caillet-Boudin et al. Molecular Neurodegeneration
- Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells
- (2015) Melissa C. Wren et al. Molecular Neurodegeneration
- Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy
- (2015) Asami Kondo et al. NATURE
- Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
- (2015) Sang-Won Min et al. NATURE MEDICINE
- Tau in physiology and pathology
- (2015) Yipeng Wang et al. NATURE REVIEWS NEUROSCIENCE
- Intracerebral injection of preformed synthetic tau fibrils initiates widespread tauopathy and neuronal loss in the brains of tau transgenic mice
- (2015) Eve Peeraer et al. NEUROBIOLOGY OF DISEASE
- Invited review: Frontotemporal dementia caused bymicrotubule-associated protein taugene (MAPT) mutations: a chameleon for neuropathology and neuroimaging
- (2015) Bernardino Ghetti et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
- (2015) Harindranath Kadavath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy
- (2015) Naomi Kouri et al. Nature Communications
- A mechanistic model of tau amyloid aggregation based on direct observation of oligomers
- (2015) Sarah L. Shammas et al. Nature Communications
- Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms
- (2015) Maxime Derisbourg et al. Scientific Reports
- A novel in vivo model of tau propagation with rapid and progressive neurofibrillary tangle pathology: the pattern of spread is determined by connectivity, not proximity
- (2014) Zeshan Ahmed et al. ACTA NEUROPATHOLOGICA
- Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains
- (2014) Susana Boluda et al. ACTA NEUROPATHOLOGICA
- Tau protein mutation P364S in two sisters: clinical course and neuropathology with emphasis on new, composite neuronal tau inclusions
- (2014) Mara Popović et al. ACTA NEUROPATHOLOGICA
- Lysine methylation is an endogenous post-translational modification of tau protein in human brain and a modulator of aggregation propensity
- (2014) Kristen E. Funk et al. BIOCHEMICAL JOURNAL
- Conformation Determines the Seeding Potencies of Native and Recombinant Tau Aggregates
- (2014) Benjamin Falcon et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
- (2014) David W. Sanders et al. NEURON
- Proteopathic tau seeding predicts tauopathy in vivo
- (2014) B. B. Holmes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau mutants bind tubulin heterodimers with enhanced affinity
- (2014) S. Elbaum-Garfinkle et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of alternative splicing of tau exon 10
- (2014) Wei Qian et al. Neuroscience Bulletin
- The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons
- (2013) Mariangela Iovino et al. ACTA NEUROPATHOLOGICA
- Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
- (2013) Florence Clavaguera et al. ACTA NEUROPATHOLOGICA
- Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
- (2013) Naomi Kouri et al. ACTA NEUROPATHOLOGICA
- Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies
- (2013) David J. Irwin et al. AMERICAN JOURNAL OF PATHOLOGY
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Neurofibrillary tangle-like tau pathology induced by synthetic tau fibrils in primary neurons over-expressing mutant tau
- (2013) Jing L. Guo et al. FEBS LETTERS
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
- (2013) M. Iba et al. JOURNAL OF NEUROSCIENCE
- Axonal transport deficits and neurodegenerative diseases
- (2013) Stéphanie Millecamps et al. NATURE REVIEWS NEUROSCIENCE
- Variation in tau isoform expression in different brain regions and disease states
- (2013) Elisa Majounie et al. NEUROBIOLOGY OF AGING
- Microtubule-associated protein tau is essential for long-term depression in the hippocampus
- (2013) T. Kimura et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- A Novel MAPT Mutation, G55R, in a Frontotemporal Dementia Patient Leads to Altered Tau Function
- (2013) Abhinaya Iyer et al. PLoS One
- Profiling Murine Tau with 0N, 1N and 2N Isoform-Specific Antibodies in Brain and Peripheral Organs Reveals Distinct Subcellular Localization, with the 1N Isoform Being Enriched in the Nucleus
- (2013) Chang Liu et al. PLoS One
- Brain homogenates from human tauopathies induce tau inclusions in mouse brain
- (2013) Florence Clavaguera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tau alternative splicing in familial and sporadic tauopathies
- (2012) Michael Niblock et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- FTDP-17 Tau Mutations Induce Distinct Effects on Aggregation and Microtubule Interactions
- (2012) Benjamin Combs et al. BIOCHEMISTRY
- MAPT expression and splicing is differentially regulated by brain region: relation to genotype and implication for tauopathies
- (2012) Daniah Trabzuni et al. HUMAN MOLECULAR GENETICS
- Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases
- (2012) Giovanni Coppola et al. HUMAN MOLECULAR GENETICS
- Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
- (2012) Katharina Flach et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Trans-cellular Propagation of Tau Aggregation by Fibrillar Species
- (2012) Najla Kfoury et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Paired Helical Filaments from Alzheimer Disease Brain Induce Intracellular Accumulation of Tau Protein in Aggresomes
- (2012) Ismael Santa-Maria et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Conformational Basis for Asymmetric Seeding Barrier in Filaments of Three- and Four-Repeat Tau
- (2012) Ayisha Siddiqua et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The MAPT p.A152T variant is a risk factor associated with tauopathies with atypical clinical and neuropathological features
- (2012) Eleanna Kara et al. NEUROBIOLOGY OF AGING
- Analyses of the MAPT, PGRN, and C9orf72 mutations in Japanese patients with FTLD, PSP, and CBS
- (2012) Kotaro Ogaki et al. PARKINSONISM & RELATED DISORDERS
- Seeding of Normal Tau by Pathological Tau Conformers Drives Pathogenesis of Alzheimer-like Tangles
- (2011) Jing L. Guo et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Neuropathology of Frontotemporal Lobar Degeneration-Tau (FTLD-Tau)
- (2011) Dennis W. Dickson et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Induction of Intracellular Tau Aggregation Is Promoted by -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau
- (2011) E. A. Waxman et al. JOURNAL OF NEUROSCIENCE
- New mutations in MAPT gene causing frontotemporal lobar degeneration: biochemical and structural characterization
- (2011) Giacomina Rossi et al. NEUROBIOLOGY OF AGING
- Post-translational modifications of tau protein: Implications for Alzheimer's disease
- (2011) Ludovic Martin et al. NEUROCHEMISTRY INTERNATIONAL
- Familial early onset frontotemporal dementia caused by a novel S356T MAPT mutation, initially diagnosed as schizophrenia
- (2010) Parastoo Momeni et al. CLINICAL NEUROLOGY AND NEUROSURGERY
- Seeded Aggregation and Toxicity of α-Synuclein and Tau
- (2010) Takashi Nonaka et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration
- (2010) Brian R. Hoover et al. NEURON
- Three Repeat Isoforms of Tau Inhibit Assembly of Four Repeat Tau Filaments
- (2010) Stephanie J. Adams et al. PLoS One
- Essential role of tau phosphorylation in adult hippocampal neurogenesis
- (2009) Xiao-Ping Hong et al. HIPPOCAMPUS
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport
- (2009) Will Stoothoff et al. JOURNAL OF NEUROCHEMISTRY
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
- (2009) Marco D Mukrasch et al. PLOS BIOLOGY
- Proline-directed Pseudo-phosphorylation at AT8 and PHF1 Epitopes Induces a Compaction of the Paperclip Folding of Tau and Generates a Pathological (MC-1) Conformation
- (2008) Sadasivam Jeganathan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons
- (2008) T. L. Spires-Jones et al. JOURNAL OF NEUROSCIENCE
- Tau exon 10 alternative splicing and tauopathies
- (2008) Fei Liu et al. Molecular Neurodegeneration
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