Dimethylaminomicheliolide ameliorates peritoneal fibrosis through the activation of autophagy

Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation

(2018) Ying Meng et al.   ANTIOXIDANTS & REDOX SIGNALING

Micheliolide alleviates hepatic steatosis in db/db mice by inhibiting inflammation and promoting autophagy via PPAR-γ-mediated NF-кB and AMPK/mTOR signaling

(2018) Juan Zhong et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Natural Product Micheliolide (MCL) Irreversibly Activates Pyruvate Kinase M2 and Suppresses Leukemia

(2018) Jing Li et al.   JOURNAL OF MEDICINAL CHEMISTRY

Targeting Toll-like receptors with soluble Toll-like receptor 2 prevents peritoneal dialysis solution–induced fibrosis

(2018) Anne-Catherine Raby et al.   KIDNEY INTERNATIONAL

Rapamycin Protects Against Peritendinous Fibrosis Through Activation of Autophagy

(2018) Wei Zheng et al.   Frontiers in Pharmacology

Complement Activation in Peritoneal Dialysis–Induced Arteriolopathy

(2017) Maria Bartosova et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

(2017) Lorenzo Galluzzi et al.   NATURE REVIEWS DRUG DISCOVERY

The triterpenoid CDDO-imidazolide ameliorates mouse liver ischemia-reperfusion injury through activating the Nrf2/HO-1 pathway enhanced autophagy

(2017) Dongwei Xu et al.   Cell Death & Disease

Atg5-mediated autophagy deficiency in proximal tubules promotes cell cycle G2/M arrest and renal fibrosis

(2016) Huiyan Li et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

The Current State of Peritoneal Dialysis

(2016) R. Mehrotra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Preventing peritoneal membrane fibrosis in peritoneal dialysis patients

(2016) Qin Zhou et al.   KIDNEY INTERNATIONAL

Changes in the worldwide epidemiology of peritoneal dialysis

(2016) Philip Kam-Tao Li et al.   Nature Reviews Nephrology

Metadherin facilitates podocyte apoptosis in diabetic nephropathy

(2016) Wen-Ting Liu et al.   Cell Death & Disease

Rapamycin Attenuates Cardiac Fibrosis in Experimental Uremic Cardiomyopathy by Reducing Marinobufagenin Levels and Inhibiting Downstream Pro‐Fibrotic Signaling

(2016) Steven T. Haller et al.   Journal of the American Heart Association

Molecular Mechanisms Underlying Peritoneal EMT and Fibrosis

(2016) Raffaele Strippoli et al.   Stem Cells International

Macrophage autophagy protects against liver fibrosis in mice

(2015) Jasper Lodder et al.   Autophagy

Essential role for the ATG4B protease and autophagy in bleomycin-induced pulmonary fibrosis

(2015) Sandra Cabrera et al.   Autophagy

mTOR: a pharmacologic target for autophagy regulation

(2015) Young Chul Kim et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapamycin Protects from Type-I Peritoneal Membrane Failure Inhibiting the Angiogenesis, Lymphangiogenesis, and Endo-MT

(2015) Guadalupe Tirma González-Mateo et al.   Biomed Research International

Atg5 deficiency-mediated mitophagy aggravates cardiac inflammation and injury in response to angiotensin II

(2014) Wei Zhao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Autophagy Regulates TGF-  Expression and Suppresses Kidney Fibrosis Induced by Unilateral Ureteral Obstruction

(2014) Y. Ding et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer

(2014) Emilie Viennois et al.   LABORATORY INVESTIGATION

Autophagy

(2013) Amber N. Hale et al.   Autophagy

Peritoneal changes in patients on long-term peritoneal dialysis

(2013) Raymond T. Krediet et al.   Nature Reviews Nephrology

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Autophagy Promotes Intracellular Degradation of Type I Collagen Induced by Transforming Growth Factor (TGF)-β1

(2012) Sung Il Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Guaianolide Sesquiterpene Lactones, a Source To Discover Agents That Selectively Inhibit Acute Myelogenous Leukemia Stem and Progenitor Cells

(2012) Quan Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Parthenolide Inhibits the LPS-induced Secretion of IL-6 and TNF-α and NF-κB Nuclear Translocation in BV-2 Microglia

(2012) Paolo Magni et al.   PHYTOTHERAPY RESEARCH

Rapamycin Ameliorates Kidney Fibrosis by Inhibiting the Activation of mTOR Signaling in Interstitial Macrophages and Myofibroblasts

(2012) Guochun Chen et al.   PLoS One

Blocking TGF- 1 Protects the Peritoneal Membrane from Dialysate-Induced Damage

(2011) J. Loureiro et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Autophagosome Formation and Molecular Mechanism of Autophagy

(2010) Isei Tanida   ANTIOXIDANTS & REDOX SIGNALING

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(2010) Noboru Mizushima et al.   CELL

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(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF- B/Snail1 pathway

(2008) R. Strippoli et al.   Disease Models & Mechanisms