Gut Leakage of Fungal-Derived Inflammatory Mediators: Part of a Gut-Liver-Kidney Axis in Bacterial Sepsis

Selective digestive and oropharyngeal decontamination in medical and surgical ICU patients: individual patient data meta-analysis

(2018) N.L. Plantinga et al.   CLINICAL MICROBIOLOGY AND INFECTION

The Synergy of Endotoxin and (1→3)-β-D-Glucan, from Gut Translocation, Worsens Sepsis Severity in a Lupus Model of Fc Gamma Receptor IIb-Deficient Mice

(2018) Jiraphorn Issara-Amphorn et al.   Journal of Innate Immunity

Gastrointestinal Colonization of Candida Albicans Increases Serum (1→3)-β-D-Glucan, without Candidemia, and Worsens Cecal Ligation and Puncture Sepsis in Murine Model

(2018) Wimonrat Panpetch et al.   SHOCK

Candida albicans -Induced Epithelial Damage Mediates Translocation through Intestinal Barriers

(2018) Stefanie Allert et al.   mBio

The Microbiome in Cirrhosis and Its Complications

(2018) Chathur Acharya et al.   Clinical Gastroenterology and Hepatology

Clinical and Physiological Perspectives of β-Glucans: The Past, Present, and Future

(2017) Khawaja Muhammad Bashir et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Fungal Mycobiome and Its Interaction with Gut Bacteria in the Host

(2017) Qi Sam et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Intestinal fungi contribute to development of alcoholic liver disease

(2017) An-Ming Yang et al.   JOURNAL OF CLINICAL INVESTIGATION

Patients with chronic kidney disease have abnormal upper gastro-intestinal tract digestive function: A study of uremic enteropathy

(2017) Claire J Grant et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Fc Gamma Receptor IIB Deficient Mice

(2017) Thunnicha Ondee et al.   SHOCK

Acyloxyacyl hydrolase promotes the resolution of lipopolysaccharide-induced acute lung injury

(2017) Benkun Zou et al.   PLoS Pathogens

Oral administration of live- or heat-killed Candida albicans worsened cecal ligation and puncture sepsis in a murine model possibly due to an increased serum (1→3)-β-D-glucan

(2017) Wimonrat Panpetch et al.   PLoS One

Role of the Gut Microbiome in Uremia: A Potential Therapeutic Target

(2016) Ali Ramezani et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Gastrointestinal and hepatic mechanisms limiting entry and dissemination of lipopolysaccharide into the systemic circulation

(2016) Mathilde Guerville et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Enteric immunity, the gut microbiome, and sepsis: Rethinking the germ theory of disease

(2016) Javier Cabrera-Perez et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure

(2016) Jean-Francois Timsit et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Endotoxemia-menace, marker, or mistake?

(2016) Robert S. Munford   JOURNAL OF LEUKOCYTE BIOLOGY

Liver — guardian, modifier and target of sepsis

(2016) Pavel Strnad et al.   Nature Reviews Gastroenterology & Hepatology

Trained immunity: A program of innate immune memory in health and disease

(2016) M. G. Netea et al.   SCIENCE

The Shift of an Intestinal “Microbiome” to a “Pathobiome” Governs the Course and Outcome of Sepsis Following Surgical Injury

(2016) Monika A. Krezalek et al.   SHOCK

Gastrointestinal Leakage Detected by Serum (1→3)-β-D-Glucan in Mouse Models and a Pilot Study in Patients with Sepsis

(2016) Asada Leelahavanichkul et al.   SHOCK

Fungi in the healthy human gastrointestinal tract

(2016) Heather E. Hallen-Adams et al.   Virulence

Microbiota and pathogen ‘pas de deux’: setting up and breaking down barriers to intestinal infection

(2016) Elizabeth S. McKenney et al.   Pathogens and Disease

Enrichment of the lung microbiome with gut bacteria in sepsis and the acute respiratory distress syndrome

(2016) Robert P. Dickson et al.   Nature Microbiology

Extreme Dysbiosis of the Microbiome in Critical Illness

(2016) Daniel McDonald et al.   mSphere

Candida Colonization as a Risk Marker for Invasive Candidiasis in Mixed Medical-Surgical Intensive Care Units: Development and Evaluation of a Simple, Standard Protocol

(2015) Anna F. Lau et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Digestive tract mycobiota: A source of infection

(2015) N. Gouba et al.   MEDECINE ET MALADIES INFECTIEUSES

(1→3)-β-D-glucan and galactomannan testing for the diagnosis of fungal peritonitis in peritoneal dialysis patients, a pilot study

(2015) Navaporn Worasilchai et al.   MEDICAL MYCOLOGY

Detection of (1→3)-β-D-glucan in same-day urine and serum samples obtained from patients with haematological malignancies

(2015) Reinhard B. Raggam et al.   MYCOSES

(1->3)- -D-Glucan and Galactomannan for Differentiating Chemical "Black Particles" and Fungal Particles Inside Peritoneal Dialysis Tubing

(2015) A. Leelahavanichkul et al.   PERITONEAL DIALYSIS INTERNATIONAL

Alkaline Phosphatase Protects Lipopolysaccharide-Induced Early Pregnancy Defects in Mice

(2015) Wei Lei et al.   PLoS One

Sepsis-Associated Acute Kidney Injury

(2015) Rashid Alobaidi et al.   SEMINARS IN NEPHROLOGY

No difference in small bowel microbiota between patients with irritable bowel syndrome and healthy controls

(2015) Aldona Dlugosz et al.   Scientific Reports

Changes in the composition of intestinal fungi and their role in mice with dextran sulfate sodium-induced colitis

(2015) Xinyun Qiu et al.   Scientific Reports

MSG-01: A Randomized, Double-Blind, Placebo-Controlled Trial of Caspofungin Prophylaxis Followed by Preemptive Therapy for Invasive Candidiasis in High-Risk Adults in the Critical Care Setting

(2014) L. Ostrosky-Zeichner et al.   CLINICAL INFECTIOUS DISEASES

Interactions Between the Intestinal Microbiome and Liver Diseases

(2014) Bernd Schnabl et al.   GASTROENTEROLOGY

Candida colonization index and subsequent infection in critically ill surgical patients: 20 years later

(2014) Philippe Eggimann et al.   INTENSIVE CARE MEDICINE

Intestinal Microbiota-Kidney Cross Talk in Acute Kidney Injury and Chronic Kidney Disease

(2014) Sanjeev Noel et al.   NEPHRON CLINICAL PRACTICE

Multistate Point-Prevalence Survey of Health Care–Associated Infections

(2014) Shelley S. Magill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Surface area of the digestive tract – revisited

(2014) Herbert F Helander et al.   SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY

Endotoxemia in End-Stage Kidney Disease

(2014) Jonathan Wong et al.   SEMINARS IN DIALYSIS

Fc gamma receptor-TLR cross-talk elicits pro-inflammatory cytokine production by human M2 macrophages

(2014) Lisa T. C. Vogelpoel et al.   Nature Communications

The Autodigestion Hypothesis for Shock and Multi-organ Failure

(2013) Geert W. Schmid-Schönbein et al.   ANNALS OF BIOMEDICAL ENGINEERING

Empirical Fluconazole versus Placebo for Intensive Care Unit Patients

(2013) Mindy G. Schuster   ANNALS OF INTERNAL MEDICINE

The Gut Microbiome, Kidney Disease, and Targeted Interventions

(2013) A. Ramezani et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Acute kidney injury is surprisingly common and a powerful predictor of mortality in surgical sepsis

(2013) Laura E. White et al.   Journal of Trauma and Acute Care Surgery

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Fungi of the Murine Gut: Episodic Variation and Proliferation during Antibiotic Treatment

(2013) Serena Dollive et al.   PLoS One

The Uremic Toxin Indoxyl Sulphate Enhances Macrophage Response to LPS

(2013) Simona Adesso et al.   PLoS One

Gut Immune Maturation Depends on Colonization with a Host-Specific Microbiota

(2012) Hachung Chung et al.   CELL

C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses

(2012) Lara M Kingeter et al.   Cellular & Molecular Immunology

Septic Shock Attributed to Candida Infection: Importance of Empiric Therapy and Source Control

(2012) M. Kollef et al.   CLINICAL INFECTIOUS DISEASES

Epidemiology, outcomes, and risk factors of invasive fungal infections in adult patients with acute myelogenous leukemia after induction chemotherapy

(2012) Dionissios Neofytos et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Comparison of the potency of a variety of β-glucans to induce cytokine production in human whole blood

(2012) Ilka Noss et al.   Innate Immunity

Colistin resistance in gram-negative bacteria during prophylactic topical colistin use in intensive care units

(2012) Evelien A. N. Oostdijk et al.   INTENSIVE CARE MEDICINE

Class B Scavenger Receptor Types I and II and CD36 Targeting Improves Sepsis Survival and Acute Outcomes in Mice

(2012) A. Leelahavanichkul et al.   JOURNAL OF IMMUNOLOGY

Chronic kidney disease alters intestinal microbial flora

(2012) Nosratola D. Vaziri et al.   KIDNEY INTERNATIONAL

Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

(2012) Christian M Karsten et al.   NATURE MEDICINE

Interactions Between Commensal Fungi and the C-Type Lectin Receptor Dectin-1 Influence Colitis

(2012) I. D. Iliev et al.   SCIENCE

Physiological-based pharmacokinetic modeling of endotoxin in the rat

(2012) Joseph C Hutter et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Leaky gut and the liver: A role for bacterial translocation in nonalcoholic steatohepatitis

(2012) Yaron Ilan   WORLD JOURNAL OF GASTROENTEROLOGY

Immune Dysfunction in Uremia—An Update

(2012) Gerald Cohen et al.   Toxins

Inflammation and gastrointestinal Candida colonization

(2011) Carol A Kumamoto   CURRENT OPINION IN MICROBIOLOGY

Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in Intensive Care Unit (ICU) and non-ICU settings in the SENTRY Antimicrobial Surveillance Program (2008–2009)

(2011) Michael A. Pfaller et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Class B Scavenger Receptor Types I and II and CD36 Mediate Bacterial Recognition and Proinflammatory Signaling Induced by Escherichia coli, Lipopolysaccharide, and Cytosolic Chaperonin 60

(2011) I. N. Baranova et al.   JOURNAL OF IMMUNOLOGY

Chronic kidney disease worsens sepsis and sepsis-induced acute kidney injury by releasing High Mobility Group Box Protein-1

(2011) Asada Leelahavanichkul et al.   KIDNEY INTERNATIONAL

Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of infection in intensive care unit study*

(2010) Daniel H. Kett et al.   CRITICAL CARE MEDICINE

Inadequate Clearance of Translocated Bacterial Products in HIV-Infected Humanized Mice

(2010) Ursula Hofer et al.   PLoS Pathogens

Gastrointestinal symptoms in intensive care patients

(2009) A. REINTAM et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

A Multicenter, Double‐Blind Trial of a High‐Dose Caspofungin Treatment Regimen versus a Standard Caspofungin Treatment Regimen for Adult Patients with Invasive Candidiasis

(2009) Robert F. Betts et al.   CLINICAL INFECTIOUS DISEASES

Candidaemia: incidence, risk factors, characteristics and outcomes in immunocompetent critically ill patients

(2009) K.Z. Vardakas et al.   CLINICAL MICROBIOLOGY AND INFECTION

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses

(2009) T. H. Mogensen   CLINICAL MICROBIOLOGY REVIEWS

Towards the human intestinal microbiota phylogenetic core

(2009) Julien Tap et al.   ENVIRONMENTAL MICROBIOLOGY

Sodium octanoate to reverse indoxyl sulfate and p-cresyl sulfate albumin binding in uremic and normal serum during sample preparation followed by fluorescence liquid chromatography

(2009) Henriette de Loor et al.   JOURNAL OF CHROMATOGRAPHY A

Animal models of sepsis and sepsis-induced kidney injury

(2009) Kent Doi et al.   JOURNAL OF CLINICAL INVESTIGATION

Candida colonisation as a source for candidaemia

(2009) L.N. Miranda et al.   JOURNAL OF HOSPITAL INFECTION

Is the LPS-mediated proteinuria mouse model relevant to human kidney disease?

(2009) Wayne D Comper   NATURE MEDICINE

Acute pancreatitis: Etiology and common pathogenesis

(2009) Guo-Jun Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Tight junctions as targets of infectious agents

(2008) Julian A. Guttman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Dectin-1 synergizes with TLR2 and TLR4 for cytokine production in human primary monocytes and macrophages

(2008) Gerben Ferwerda et al.   CELLULAR MICROBIOLOGY

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

(2008) Kevin M. Dennehy et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Chylomicrons promote intestinal absorption of lipopolysaccharides

(2008) Sarbani Ghoshal et al.   JOURNAL OF LIPID RESEARCH

AP214, an analogue of α-melanocyte-stimulating hormone, ameliorates sepsis-induced acute kidney injury and mortality

(2008) K. Doi et al.   KIDNEY INTERNATIONAL

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

The role of the cell wall in fungal pathogenesis

(2008) David M. Arana et al.   Microbial Biotechnology