Hepatocellular autophagy modulates the unfolded protein response and fasting-induced steatosis in mice

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

(2015) Daniela Senft et al.   TRENDS IN BIOCHEMICAL SCIENCES

Chromosomal mapping of the GFP-LC3 transgene in GFP-LC3 mice

(2014) Akiko Kuma et al.   Autophagy

Autophagy inhibits oxidative stress and tumor suppressors to exert its dual effect on hepatocarcinogenesis

(2014) Y Tian et al.   CELL DEATH AND DIFFERENTIATION

Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming

(2014) Atsushi Miyajima et al.   Cell Stem Cell

Nrf2 promotes the development of fibrosis and tumorigenesis in mice with defective hepatic autophagy

(2014) Hong-Min Ni et al.   JOURNAL OF HEPATOLOGY

Autophagy—a key player in cellular and body metabolism

(2014) Kook Hwan Kim et al.   Nature Reviews Endocrinology

Role of endoplasmic reticulum stress in the pathogenesis of nonalcoholic fatty liver disease

(2014) Xue-Qun Zhang   WORLD JOURNAL OF GASTROENTEROLOGY

Role of autophagy in the pathophysiology of nonalcoholic fatty liver disease: A controversial issue

(2014) Wilhelmus J Kwanten   WORLD JOURNAL OF GASTROENTEROLOGY

Impaired autophagic flux is associated with increased endoplasmic reticulum stress during the development of NAFLD

(2014) Á González-Rodríguez et al.   Cell Death & Disease

Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment

(2014) Liang Ge et al.   eLife

Functions of autophagy in normal and diseased liver

(2013) Mark J. Czaja et al.   Autophagy

Inhibition of hepatocyte autophagy increases tumor necrosis factor-dependent liver injury by promoting caspase-8 activation

(2013) M Amir et al.   CELL DEATH AND DIFFERENTIATION

The eIF2α kinases: their structures and functions

(2013) Neysan Donnelly et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease

(2013) Karima Begriche et al.   HEPATOLOGY

Autophagy Deficiency by Hepatic FIP200 Deletion Uncouples Steatosis From Liver Injury in NAFLD

(2013) Di Ma et al.   MOLECULAR ENDOCRINOLOGY

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcriptional Control of Hepatic Lipid Metabolism by SREBP and ChREBP

(2013) Xu Xu et al.   SEMINARS IN LIVER DISEASE

Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments

(2013) Matthew D. Shoulders et al.   Cell Reports

Analysis of macroautophagy by immunohistochemistry

(2012) Mathias T. Rosenfeldt et al.   Autophagy

Immunohistochemical analysis of macroautophagy

(2012) Wim Martinet et al.   Autophagy

Mitophagy: mechanisms, pathophysiological roles, and analysis

(2012) Wen-Xing Ding et al.   BIOLOGICAL CHEMISTRY

Features, Diagnosis, and Treatment of Nonalcoholic Fatty Liver Disease

(2012) Dawn M. Torres et al.   Clinical Gastroenterology and Hepatology

Autophagy deficiency leads to protection from obesity and insulin resistance by inducing Fgf21 as a mitokine

(2012) Kook Hwan Kim et al.   NATURE MEDICINE

Systematic review: the epidemiology and natural history of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis in adults

(2011) G. Vernon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Autophagy-deficient mice develop multiple liver tumors

(2011) A. Takamura et al.   GENES & DEVELOPMENT

Contributions of new hepatocyte lineages to liver growth, maintenance, and regeneration in mice

(2011) Sonya V. Iverson et al.   HEPATOLOGY

The contribution of endoplasmic reticulum stress to liver diseases

(2011) Lily Dara et al.   HEPATOLOGY

Activating transcription factor 6 plays protective and pathological roles in steatosis due to endoplasmic reticulum stress in zebrafish

(2011) Ayca Cinaroglu et al.   HEPATOLOGY

Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells

(2011) Yoshihiro Inami et al.   JOURNAL OF CELL BIOLOGY

Ductal plates in hepatic ductular reactions. Hypothesis and implications. I. Types of ductular reaction reconsidered

(2011) Valeer J. Desmet   VIRCHOWS ARCHIV

Endoplasmic Reticulum Stress and the Unfolded Protein Response in Nonalcoholic Fatty Liver Disease

(2010) Christopher L. Gentile et al.   ANTIOXIDANTS & REDOX SIGNALING

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

The MAP1-LC3 conjugation system is involved in lipid droplet formation

(2009) Masahiro Shibata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The alpha-fetoprotein enhancer region activates the albumin and alpha-fetoprotein promoters during liver development

(2009) Lin Jin et al.   DEVELOPMENTAL BIOLOGY

Accelerated Fatty Acid Oxidation in Muscle Averts Fasting-induced Hepatic Steatosis in SJL/J Mice

(2009) Hong-Ping Guan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome

(2009) Claudio Hetz et al.   MOLECULAR CELL

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

JNK1-Mediated Phosphorylation of Bcl-2 Regulates Starvation-Induced Autophagy

(2008) Yongjie Wei et al.   MOLECULAR CELL

Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

(2008) Scott L. Friedman   PHYSIOLOGICAL REVIEWS