The contribution of endoplasmic reticulum stress to liver diseases

Role of ATF4 in regulation of autophagy and resistance to drugs and hypoxia

(2011) Tomasz Rzymski et al.   CELL CYCLE

Bortezomib blocks the catabolic process of autophagy via a cathepsin-dependent mechanism, affects endoplasmic reticulum stress, and induces caspase-dependent cell death in antiestrogen–sensitive and resistant ER+ breast cancer cells

(2010) Sudharsan Periyasamy-Thandavan et al.   Autophagy

Translational control of the sterol-regulatory transcription factor SREBP-1 mRNA in response to serum starvation or ER stress is mediated by an internal ribosome entry site

(2010) Fabrizio Damiano et al.   BIOCHEMICAL JOURNAL

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

(2010) P. Ferré et al.   DIABETES OBESITY & METABOLISM

Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites

(2010) Brent A. Neuschwander-Tetri   HEPATOLOGY

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro

(2010) Po-Yuan Ke et al.   JOURNAL OF CLINICAL INVESTIGATION

In vivo hepatic endoplasmic reticulum stress in patients with chronic hepatitis C

(2010) Tarik Asselah et al.   JOURNAL OF PATHOLOGY

HIV protease inhibitor lopinavir-induced TNF-α and IL-6 expression is coupled to the unfolded protein response and ERK signaling pathways in macrophages

(2009) Li Chen et al.   BIOCHEMICAL PHARMACOLOGY

Pharmacokinetics of Acetaminophen-Protein Adducts in Adults with Acetaminophen Overdose and Acute Liver Failure

(2009) L. P. James et al.   DRUG METABOLISM AND DISPOSITION

Apolipoprotein B100 acts as a molecular link between lipid-induced endoplasmic reticulum stress and hepatic insulin resistance

(2009) Qiaozhu Su et al.   HEPATOLOGY

Epigenetic regulation of hepatic endoplasmic reticulum stress pathways in the ethanol-fed cystathionine beta synthase-deficient mouse

(2009) Farah Esfandiari et al.   HEPATOLOGY

Differences in betaine-homocysteine methyltransferase expression, endoplasmic reticulum stress response, and liver injury between alcohol-fed mice and rats

(2009) Masao Shinohara et al.   HEPATOLOGY

Structural and functional link between the mitochondrial network and the endoplasmic reticulum

(2009) Carlotta Giorgi et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Homocysteine Supplementation Attenuates the Unfolded Protein Response in a Murine Nutritional Model of Steatohepatitis

(2009) Anne S. Henkel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Phosphorylation of Eukaryotic Translation Initiation Factor 2  Coordinates rRNA Transcription and Translation Inhibition during Endoplasmic Reticulum Stress

(2009) J. B. DuRose et al.   MOLECULAR AND CELLULAR BIOLOGY

Insulin Regulates TRB3 and Other Stress-Responsive Gene Expression through Induction of C/EBPβ

(2009) Keyong Du et al.   MOLECULAR ENDOCRINOLOGY

BGP-15 inhibits caspase-independent programmed cell death in acetaminophen-induced liver injury

(2009) Gábor Nagy et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effect of Transgenic Extrahepatic Expression of Betaine-Homocysteine Methyltransferase on Alcohol or Homocysteine-Induced Fatty Liver

(2008) Cheng Ji et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

CHOP deficiency attenuates cholestasis-induced liver fibrosis by reduction of hepatocyte injury

(2008) Nobuyuki Tamaki et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice

(2008) Seiichi Oyadomari et al.   Cell Metabolism

UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators

(2008) D. Thomas Rutkowski et al.   DEVELOPMENTAL CELL

Endoplasmic Reticulum Stress Is Reduced in Tissues of Obese Subjects After Weight Loss

(2008) M. F. Gregor et al.   DIABETES

Increase in Endoplasmic Reticulum Stress-Related Proteins and Genes in Adipose Tissue of Obese, Insulin-Resistant Individuals

(2008) G. Boden et al.   DIABETES

Induction of incomplete autophagic response by hepatitis C virus via the unfolded protein response

(2008) Donna Sir et al.   HEPATOLOGY

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION

Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injury

(2008) Cheng Ji   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress

(2008) Irina M Bochkis et al.   NATURE MEDICINE

Chromium Alleviates Glucose Intolerance, Insulin Resistance, and Hepatic ER Stress in Obese Mice

(2008) Nair Sreejayan et al.   Obesity

Regulation of Hepatic Lipogenesis by the Transcription Factor XBP1

(2008) A.-H. Lee et al.   SCIENCE

Mechanisms of Disease Progression in Nonalcoholic Fatty Liver Disease

(2008) Janice Jou et al.   SEMINARS IN LIVER DISEASE

Direct monitoring of in vivo ER stress during the development of insulin resistance with ER stress-activated indicator transgenic mice

(2007) Kazutomi Yoshiuchi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS