Easy Access to 1-Amino and 1-Carbon Substituted Isoquinolines via Cobalt-Catalyzed CH/NO Bond Activation

Cobalt(iii) catalyzed C-8 selective C–H and C–O coupling of quinoline N-oxide with internal alkynes via C–H activation and oxygen atom transfer

(2016) Nagaraju Barsu et al.   CHEMICAL COMMUNICATIONS

Cobalt Catalysis Involving π Components in Organic Synthesis

(2015) Parthasarathy Gandeepan et al.   ACCOUNTS OF CHEMICAL RESEARCH

Rhodium(III)-Catalyzedortho-Arylation of Anilides with Aryl Halides

(2015) Radhakrishnan Haridharan et al.   ADVANCED SYNTHESIS & CATALYSIS

Rhodium(III)-Catalyzed in situ Oxidizing Directing Group- Assisted CH Bond Activation and Olefination: A Route to 2-Vinylanilines

(2015) Krishnamoorthy Muralirajan et al.   ADVANCED SYNTHESIS & CATALYSIS

Cp*CoIIICatalyzed Site-Selective CH Activation of UnsymmetricalO-Acyl Oximes: Synthesis of Multisubstituted Isoquinolines from Terminal and Internal Alkynes

(2015) Bo Sun et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dehydrative Direct CH Allylation with Allylic Alcohols under [Cp*CoIII] Catalysis

(2015) Yudai Suzuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt(III)-Catalyzed Aryl and Alkenyl CH Aminocarbonylation with Isocyanates and Acyl Azides

(2015) Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt(III)-Catalyzed Directed CH Coupling with Diazo Compounds: Straightforward Access towards Extended π-Systems

(2015) Dongbing Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Comparative Catalytic Activity of Group 9 [Cp*MIII] Complexes: Cobalt-Catalyzed CH Amidation of Arenes with Dioxazolones as Amidating Reagents

(2015) Juhyeon Park et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rh-catalyzed oxidizing group-directed ortho C–H vinylation of arenes by vinylstannanes

(2015) Sekar Prakash et al.   CHEMICAL COMMUNICATIONS

Cobalt(III)-Catalyzed Dehydrative [4+2] Annulation of Oxime with Alkyne by CH and NOH Activation

(2015) Malay Sen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt(III)-Catalyzed CH/NO Functionalizations: Isohypsic Access to Isoquinolines

(2015) Hui Wang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Transition-Metal-Catalyzed π-Bond-Assisted CH Bond Functionalization: An Emerging Trend in Organic Synthesis

(2015) Parthasarathy Gandeepan et al.   Chemistry-An Asian Journal

Modification of 3-arylisoquinolines into 3,4-diarylisoquinolines and assessment of their cytotoxicity and topoisomerase inhibition

(2015) Daulat Bikram Khadka et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Selective Cyclization of Arylnitrones to Indolines under External Oxidant-Free Conditions: Dual Role of Rh(III) Catalyst in the C–H Activation and Oxygen Atom Transfer

(2015) Ramesh B. Dateer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt Catalyzed C–H and N–H Bond Annulation of Sulfonamide with Terminal and Internal Alkynes

(2015) Deepti Kalsi et al.   ORGANIC LETTERS

Cobalt(III)-Catalyzed C–H Bond Amidation with Isocyanates

(2015) Joshua R. Hummel et al.   ORGANIC LETTERS

Cobalt-Catalyzed C–H Cyanation of (Hetero)arenes and 6-Arylpurines with N-Cyanosuccinimide as a New Cyanating Agent

(2015) Amit B. Pawar et al.   ORGANIC LETTERS

Cobalt(III)-Catalyzed C–H Amidation of Arenes using Acetoxycarbamates as Convenient Amino Sources under Mild Conditions

(2015) Pitambar Patel et al.   ACS Catalysis

Air-Stable Carbonyl(pentamethylcyclopentadienyl)cobalt Diiodide Complex as a Precursor for Cationic (Pentamethylcyclopentadienyl)cobalt(III) Catalysis: Application for Directed C-2 Selective CH Amidation of Indoles

(2014) Bo Sun et al.   ADVANCED SYNTHESIS & CATALYSIS

Regioselective Synthesis of IndolesviaRhodium-Catalyzed CH Activation Directed by anIn-SituGenerated Redox-Neutral Group

(2014) Krishnamoorthy Muralirajan et al.   ADVANCED SYNTHESIS & CATALYSIS

Formal SN-Type Reactions in Rhodium(III)-Catalyzed CH Bond Activation

(2014) Nadine Kuhl et al.   ADVANCED SYNTHESIS & CATALYSIS

Cobalt-Catalyzed, Aminoquinoline-Directed C(sp2)H Bond Alkenylation by Alkynes

(2014) Liene Grigorjeva et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

One-Pot Synthesis of Highly Substituted Polyheteroaromatic Compounds by Rhodium(III)-Catalyzed Multiple CH Activation and Annulation

(2014) Jayachandran Jayakumar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt-Catalyzed CH Cyanation of Arenes and Heteroarenes

(2014) Jie Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amidines for Versatile Ruthenium(II)-Catalyzed Oxidative CH Activations with Internal Alkynes and Acrylates

(2014) Jie Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium-Catalyzed Synthesis of Isoquinolines and Indenes from Benzylidenehydrazones and Internal Alkynes

(2014) Xiao-Cheng Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

Pyrroloindolone Synthesis via a Cp*CoIII-Catalyzed Redox-Neutral Directed C–H Alkenylation/Annulation Sequence

(2014) Hideya Ikemoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C–H Bond Functionalization/Addition/Cyclization Cascades

(2014) Joshua R. Hummel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Co(III)-Catalyzed C–H Activation/Formal SN-Type Reactions: Selective and Efficient Cyanation, Halogenation, and Allylation

(2014) Da-Gang Yu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Hydroarylative Cyclization of 1,6-Enynes with Aromatic Ketones and Esters via C–H Activation

(2014) Rajagopal Santhoshkumar et al.   ORGANIC LETTERS

Isoquinoline skeleton synthesis via chelation-assisted C−H activation

(2014) Ruoyu He et al.   TETRAHEDRON LETTERS

Rh(iii)-catalyzed C–H functionalization/aromatization cascade with 1,3-dienes: a redox-neutral and regioselective access to isoquinolines

(2014) Dongbing Zhao et al.   Chemical Science

A Cationic High-Valent Cp*CoIIIComplex for the Catalytic Generation of Nucleophilic Organometallic Species: Directed CH Bond Activation

(2013) Tatsuhiko Yoshino et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A regioselective synthesis of 1-haloisoquinolines via ruthenium-catalyzed cyclization of O-methylbenzohydroximoyl halides with alkynes

(2013) Ravi Kiran Chinnagolla et al.   CHEMICAL COMMUNICATIONS

A convenient synthesis of quinolizinium salts through Rh(iii) or Ru(ii)-catalyzed C–H bond activation of 2-alkenylpyridines

(2013) Ching-Zong Luo et al.   CHEMICAL COMMUNICATIONS

Cp*CoIII-Catalyzed C2-Selective Addition of Indoles to Imines

(2013) Tatsuhiko Yoshino et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed Synthesis of Cinnolinium Salts from Azobenzenes and Alkynes: Application to the Synthesis of Indoles and Cinnolines

(2013) Krishnamoorthy Muralirajan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt-Catalyzed Ortho Alkylation of Aromatic Imines with Primary and Secondary Alkyl Halides

(2013) Ke Gao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Isoquinolines via Rh(III)-Catalyzed C–H Activation Using Hydrazone as a New Oxidizing Directing Group

(2013) Sheng-Chieh Chuang et al.   ORGANIC LETTERS

Cobalt-Catalyzed Direct Arylation and Benzylation by CH/CO Cleavage with Sulfamates, Carbamates, and Phosphates

(2012) Weifeng Song et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild Rhodium(III)-Catalyzed CH Activation and Intermolecular Annulation with Allenes

(2012) Honggen Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium(III)-Catalyzed Oxidative CH Coupling ofN-Methoxybenzamides with Aryl Boronic Acids: One-Pot Synthesis of Phenanthridinones

(2012) Jaganathan Karthikeyan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

C–C, C–O and C–N bond formation via rhodium(iii)-catalyzed oxidative C–H activation

(2012) Guoyong Song et al.   CHEMICAL SOCIETY REVIEWS

Synthesis of Isoquinolines and Heterocycle-Fused Pyridines via Three-Component Cascade Reaction of Aryl Ketones, Hydroxylamine, and Alkynes

(2012) Liyao Zheng et al.   JOURNAL OF ORGANIC CHEMISTRY

Cationic Ruthenium Catalysts for Alkyne Annulations with Oximes by C–H/N–O Functionalizations

(2012) Christoph Kornhaaß et al.   JOURNAL OF ORGANIC CHEMISTRY

Rh(III)-Catalyzed Regioselective Synthesis of Pyridines from Alkenes and α,β-Unsaturated Oxime Esters

(2012) Jamie M. Neely et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzed Ortho-Arylation of Aromatic Imines with Aryl Chlorides

(2012) Ke Gao et al.   ORGANIC LETTERS

Ru(II)-Catalyzed Amidation of 2-Arylpyridines with Isocyanates via C–H Activation

(2012) Krishnamoorthy Muralirajan et al.   ORGANIC LETTERS

Ruthenium-Catalyzed Highly Regioselective Cyclization of Ketoximes with Alkynes by C–H Bond Activation: A Practical Route to Synthesize Substituted Isoquinolines

(2012) Ravi Kiran Chinnagolla et al.   ORGANIC LETTERS

Synthesis of Isoquinolines via Rhodium(III)-Catalyzed Dehydrative CC and CN Coupling between Oximines and Alkynes

(2011) Xingping Zhang et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Isoquinolines from α-Aryl Vinyl Azides and Internal Alkynes by Rh-Cu Bimetallic Cooperation

(2011) Yi-Feng Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regioselective Synthesis of Indenols by Rhodium-Catalyzed CH Activation and Carbocyclization of Aryl Ketones and Alkynes

(2011) Krishnamoorthy Muralirajan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Pyridine synthesis from oximes and alkynesviarhodium(iii) catalysis: Cp* and Cptprovide complementary selectivity

(2011) Todd K. Hyster et al.   CHEMICAL COMMUNICATIONS

Towards mild metal-catalyzed C–H bond activation

(2011) Joanna Wencel-Delord et al.   CHEMICAL SOCIETY REVIEWS

Recent advances in the transition metal-catalyzed twofold oxidative C–H bond activation strategy for C–C and C–N bond formation

(2011) Seung Hwan Cho et al.   CHEMICAL SOCIETY REVIEWS

The Catalytic Ability of Various Transition Metals in the Direct Functionalization of Aromatic CH Bonds

(2011) Hu Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Cobalt-Catalyzed Direct Arylation of Unactivated Arenes with Aryl Halides

(2011) Wei Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Ruthenium-Catalyzed Isoquinolone Synthesis through CH Activation Using an Oxidizing Directing Group

(2011) Bin Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Nickel-Catalyzed Cyclization of ortho-Iodoketoximes and ortho-Iodoketimines with Alkynes: Synthesis of Highly Substituted Isoquinolines and Isoquinolinium Salts

(2011) Wei-Chun Shih et al.   Chemistry-An Asian Journal

Synthesis of Azaheterocycles from Aryl KetoneO-Acetyl Oximes and Internal Alkynes by Cu–Rh Bimetallic Relay Catalysts

(2011) Pei Chui Too et al.   JOURNAL OF ORGANIC CHEMISTRY

Computational Elucidation of the Internal Oxidant-Controlled Reaction Pathways in Rh(III)-Catalyzed Aromatic C–H Functionalization

(2011) Liang Xu et al.   JOURNAL OF ORGANIC CHEMISTRY

Organic Electrodes Based on Grafted Oligothiophene Units in Ultrathin, Large-Area Molecular Junctions

(2011) Pascal Martin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies

(2011) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of 1-Aminoisoquinolines via Rh(III)-Catalyzed Oxidative Coupling

(2011) Xiaohong Wei et al.   ORGANIC LETTERS

Pd-catalyzed oxidative coupling with organometallic reagents via C–H activation

(2010) Chang-Liang Sun et al.   CHEMICAL COMMUNICATIONS

Oxidative Coupling of Aromatic Substrates with Alkynes and Alkenes under Rhodium Catalysis

(2010) Tetsuya Satoh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

(2010) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Amination of Aromatic C−H Bonds with Oxime Esters

(2010) Yichen Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cobalt-Catalyzedortho-Alkylation of Secondary Benzamide with Alkyl Chloride through Directed C−H Bond Activation

(2010) Quan Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Therapeutic potential of nucleic acid-binding isoquinoline alkaloids: Binding aspects and implications for drug design

(2010) Kakali Bhadra et al.   MEDICINAL RESEARCH REVIEWS

Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl KetoneO-Acyloxime Derivatives and Internal Alkynes

(2010) Pei Chui Too et al.   ORGANIC LETTERS

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-catalyzed oxidative coupling of aromatic imines with internal alkynes via regioselective C–H bond cleavage

(2009) Tatsuya Fukutani et al.   CHEMICAL COMMUNICATIONS

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

Isoquinolinium Salts fromo-Halobenzaldehydes, Amines, and Alkynes Catalyzed by Nickel Complexes: Synthesis and Applications

(2009) Rajendra Prasad Korivi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Easy Access to Isoquinolines and Tetrahydroquinolines from Ketoximes and Alkynes via Rhodium-Catalyzed C−H Bond Activation

(2009) Kanniyappan Parthasarathy et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C−H Bond Activation

(2008) Jared C. Lewis et al.   ACCOUNTS OF CHEMICAL RESEARCH

Synthesis of Dihydropyridines and Pyridines from Imines and Alkynes via C−H Activation

(2008) Denise A. Colby et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY