Towards mild metal-catalyzed C–H bond activation

Oxidizing Directing Groups Enable Efficient and Innovative CH Activation Reactions

(2011) Frederic W. Patureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Direct Addition of Aryl CH Bonds to N-Sulfonyl Aldimines

(2011) Yang Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Carboxylate-Assisted Transition-Metal-Catalyzed C−H Bond Functionalizations: Mechanism and Scope

(2011) Lutz Ackermann   CHEMICAL REVIEWS

Recent developments in natural product synthesis using metal-catalysed C–H bond functionalisation

(2011) Lindsay McMurray et al.   CHEMICAL SOCIETY REVIEWS

RhIII-Catalyzed Oxidative Olefination of Vinylic CH Bonds: Efficient and Selective Access to Di-unsaturated α-Amino Acid Derivatives and Other Linear 1,3-Butadienes

(2011) Tatiana Besset et al.   CHEMISTRY-A EUROPEAN JOURNAL

Rhodium(III)-Catalyzed Arylation of Boc-Imines via C−H Bond Functionalization

(2011) Andy S. Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh(III)-Catalyzed Directed C−H Olefination Using an Oxidizing Directing Group: Mild, Efficient, and Versatile

(2011) Souvik Rakshit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse Strategies toward Indenol and Fulvene Derivatives: Rh-Catalyzed C−H Activation of Aryl Ketones Followed by Coupling with Internal Alkynes

(2011) Frederic W. Patureau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Convergent Total Synthesis of (+)-Lithospermic Acid via a Late-Stage Intermolecular C−H Olefination

(2011) Dong-Hui Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Heterocycle Synthesis Using an Internal Oxidant: Improved Reactivity and Mechanistic Studies

(2011) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Constructing Multiply Substituted Arenes Using Sequential Palladium(II)-Catalyzed CH Olefination

(2010) Keary M. Engle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Bond Arylation of Electron-Deficient Arenes at Room Temperature

(2010) Matthew J. Tredwell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed Oxidative Olefination of CH Bonds in Acetophenones and Benzamides

(2010) Frederic W. Patureau et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Highly Para-Selective Copper(II)-Catalyzed Direct Arylation of Aniline and Phenol Derivatives

(2010) Claire-Lise Ciana et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper(II)-Catalyzed meta-Selective Direct Arylation of α-Aryl Carbonyl Compounds

(2010) Hung A. Duong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Vinyl Moiety as a Handle for Regiocontrol in the Preparation of Unsymmetrical 2,3-Aliphatic-Substituted Indoles and Pyrroles

(2010) Malcolm P. Huestis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Ligand-Directed C−H Functionalization Reactions

(2010) Thomas W. Lyons et al.   CHEMICAL REVIEWS

C—H Bond Activation in Transition Metal Species from a Computational Perspective

(2010) David Balcells et al.   CHEMICAL REVIEWS

Overview of the Mechanistic Work on the Concerted Metallation–Deprotonation Pathway

(2010) David Lapointe et al.   CHEMISTRY LETTERS

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Mechanistic Analysis of AzineN-Oxide Direct Arylation: Evidence for a Critical Role of Acetate in the Pd(OAc)2Precatalyst

(2010) Ho-Yan Sun et al.   JOURNAL OF ORGANIC CHEMISTRY

Predictable and Site-Selective Functionalization of Poly(hetero)arene Compounds by Palladium Catalysis

(2010) David Lapointe et al.   JOURNAL OF ORGANIC CHEMISTRY

Rhodium(III)-Catalyzed Isoquinolone Synthesis: The N−O Bond as a Handle for C−N Bond Formation and Catalyst Turnover

(2010) Nicolas Guimond et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium-Catalyzed Synthesis of Silafluorene Derivatives via Cleavage of Silicon−Hydrogen and Carbon−Hydrogen Bonds

(2010) Tomonari Ureshino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cationic Palladium(II) Catalysis: C−H Activation/Suzuki−Miyaura Couplings at Room Temperature

(2010) Takashi Nishikata et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ligand-Accelerated C−H Activation Reactions: Evidence for a Switch of Mechanism

(2010) Keary M. Engle et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

On the Mechanism of Palladium-Catalyzed Aromatic C−H Oxidation

(2010) David C. Powers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Investigation of the Mechanism of C(sp3)−H Bond Cleavage in Pd(0)-Catalyzed Intramolecular Alkane Arylation Adjacent to Amides and Sulfonamides

(2010) Sophie Rousseaux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rhodium(III)-Catalyzed Arene and Alkene C−H Bond Functionalization Leading to Indoles and Pyrroles

(2010) David R. Stuart et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rh Catalyzed Olefination and Vinylation of Unactivated Acetanilides

(2010) Frederic W. Patureau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Benzylic Addition of 2-Methyl Azaarenes toN-Sulfonyl Aldimines via C−H Bond Activation

(2010) Bo Qian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room-Temperature Regioselective C−H/Olefin Coupling of Aromatic Ketones Using an Activated Ruthenium Catalyst with a Carbonyl Ligand and Structural Elucidation of Key Intermediates

(2010) Fumitoshi Kakiuchi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room Temperature Palladium-Catalyzed Decarboxylativeortho-Acylation of Acetanilides with α-Oxocarboxylic Acids

(2010) Ping Fang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bimetallic Reductive Elimination from Dinuclear Pd(III) Complexes

(2010) David C. Powers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cationic Pd(II)-Catalyzed Fujiwara−Moritani Reactions at Room Temperature in Water

(2010) Takashi Nishikata et al.   ORGANIC LETTERS

Synthesis of β- and γ-Carbolinones via Pd-Catalyzed Direct Dehydrogenative Annulation (DDA) of Indole-carboxamides with Alkynes Using Air as the Oxidant

(2010) Zhuangzhi Shi et al.   ORGANIC LETTERS

Room-Temperature Direct Arylation of Polyfluorinated Arenes under Biphasic Conditions

(2010) Olivier René et al.   ORGANIC LETTERS

Facile Benzo-Ring Construction via Palladium-Catalyzed Functionalization of Unactivated sp3C−H Bonds under Mild Reaction Conditions

(2010) Yiqing Feng et al.   ORGANIC LETTERS

Chelate-Assisted Oxidative Coupling Reaction of Arylamides and Unactivated Alkenes: Mechanistic Evidence for Vinyl C−H Bond Activation Promoted by an Electrophilic Ruthenium Hydride Catalyst

(2010) Ki-Hyeok Kwon et al.   ORGANOMETALLICS

Amine directed Pd(ii)-catalyzed C–H bond functionalization under ambient conditions

(2010) Benjamin Haffemayer et al.   Chemical Science

Palladium-Catalyzed Oxidation of Phenyl-Substituted Alkenes using Molecular Oxygen as the Sole Oxidant

(2009) Aline C. Bueno et al.   ADVANCED SYNTHESIS & CATALYSIS

Room Temperature CH Activation and Cross-Coupling of Aryl Ureas in Water

(2009) Takashi Nishikata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iridium-Catalyzed Reactions of Trifluoromethylated Compounds with Alkenes: A Csp3H Bond Activation α to the Trifluoromethyl Group

(2009) Yong Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Room-Temperature Palladium-Catalyzed CH Activation:ortho-Carbonylation of Aniline Derivatives

(2009) Chris E. Houlden et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Palladium-Catalyzed Oxidative Cycloaromatization of Biaryls with Alkynes Using Molecular Oxygen as the Oxidant

(2009) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Indoles from Simple Anilines and Alkynes: Palladium-Catalyzed CH Activation Using Dioxygen as the Oxidant

(2009) Zhuangzhi Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed CH Activation/CC Cross-Coupling Reactions: Versatility and Practicality

(2009) Xiao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

High-Oxidation-State Palladium Catalysis: New Reactivity for Organic Synthesis

(2009) Kilian Muñiz   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rhodium-Catalyzed C−C Bond Formation via Heteroatom-Directed C−H Bond Activation

(2009) Denise A. Colby et al.   CHEMICAL REVIEWS

Transition metal-catalyzed C–H activation reactions: diastereoselectivity and enantioselectivity

(2009) Ramesh Giri et al.   CHEMICAL SOCIETY REVIEWS

Organopalladium(iv) chemistry

(2009) Ling-Min Xu et al.   CHEMICAL SOCIETY REVIEWS

Construction of Nitrogen-Containing Heterocycles by CH Bond Functionalization

(2009) Praew Thansandote et al.   CHEMISTRY-A EUROPEAN JOURNAL

Palladium-Catalyzed Direct Synthesis of Carbazoles via One-PotN-Arylation and Oxidative Biaryl Coupling: Synthesis and Mechanistic Study

(2009) Toshiaki Watanabe et al.   JOURNAL OF ORGANIC CHEMISTRY

C−C Bond Formation via C−H Bond Activation Under Protic Conditions: On the Role of Phosphane Ligand and Cosolvent

(2009) Marc-Olivier Simon et al.   JOURNAL OF ORGANIC CHEMISTRY

A Catalytic, Brønsted Base Strategy for Intermolecular Allylic C−H Amination

(2009) Sean A. Reed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Direct Arylation of Azine and AzoleN-Oxides: Reaction Development, Scope and Applications in Synthesis

(2009) Louis-Charles Campeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ruthenium-Catalyzed Carbonylation at Ortho C−H Bonds in Aromatic Amides Leading to Phthalimides: C−H Bond Activation Utilizing a Bidentate System

(2009) Satoshi Inoue et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Allylic C−H Amination for the Preparation ofsyn-1,3-Amino Alcohol Motifs

(2009) Grant T. Rice et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatile Pd(OTf)2·2H2O-Catalyzedortho-Fluorination Using NMP as a Promoter

(2009) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Olefination of Electron-Deficient Arenes Using 2,6-Dialkylpyridine Ligands

(2009) Yang-Hui Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bimetallic Palladium Catalysis: Direct Observation of Pd(III)−Pd(III) Intermediates

(2009) David C. Powers et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed Enantioselective C−H Olefination of Diphenylacetic Acids

(2009) Bing-Feng Shi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzed C−H Activation/Aryl−Aryl Coupling of Phenol Esters

(2009) Bin Xiao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total synthesis and study of 6-deoxyerythronolide B by late-stage C–H oxidation

(2009) Erik M. Stang et al.   Nature Chemistry

Ligand-Enabled Reactivity and Selectivity in a Synthetically Versatile Aryl C-H Olefination

(2009) D.-H. Wang et al.   SCIENCE

A Meta-Selective Copper-Catalyzed C-H Bond Arylation

(2009) R. J. Phipps et al.   SCIENCE

Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C−H Bond Activation

(2008) Jared C. Lewis et al.   ACCOUNTS OF CHEMICAL RESEARCH

PdII-Catalyzed Enantioselective Activation of C(sp2)H and C(sp3)H Bonds Using Monoprotected Amino Acids as Chiral Ligands

(2008) Bing-Feng Shi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

PdII‐Catalyzed MonoselectiveorthoHalogenation of CH Bonds Assisted by Counter Cations: A Complementary Method to Directedortho Lithiation

(2008) Tian‐Sheng Mei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Oxidative Cyclization ofN-Aryl Enamines: From Anilines to Indoles

(2008) Sebastian Würtz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids

(2008) Shang-Dong Yang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intramolecular Pd(II)-Catalyzed Oxidative Biaryl Synthesis Under Air: Reaction Development and Scope

(2008) Benoît Liégault et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Direct C-2 Arylation of Indoles with Potassium Aryltrifluoroborate Salts

(2008) Jinlong Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Intramolecular Hydroarylation of Alkenes via Directed C−H Bond Activation

(2008) Hitoshi Harada et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric Synthesis of (−)-Incarvillateine Employing an Intramolecular Alkylation via Rh-Catalyzed Olefinic C−H Bond Activation

(2008) Andy S. Tsai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Distinct Reactivity of Pd(OTs)2: The Intermolecular Pd(II)-Catalyzed 1,2-Carboamination of Dienes

(2008) Chris E. Houlden et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

C2, C5, and C4 AzoleN-Oxide Direct Arylation Including Room-Temperature Reactions

(2008) Louis-Charles Campeau et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Intermolecular Linear Allylic C−H Amination via Heterobimetallic Catalysis

(2008) Sean A. Reed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Oxidative Pd(II)-Catalyzed C−H Bond Amination to Carbazole at Ambient Temperature

(2008) James A. Jordan-Hore et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Strategy for C−H Activation of Pyridines:  Direct C-2 Selective Alkenylation of Pyridines by Nickel/Lewis Acid Catalysis

(2008) Yoshiaki Nakao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room Temperature and Phosphine Free Palladium Catalyzed Direct C-2 Arylation of Indoles

(2008) Nathalie Lebrasseur et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu(II)-Catalyzed Direct and Site-Selective Arylation of Indoles Under Mild Conditions

(2008) Robert J. Phipps et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Intermolecular Allylic CH Alkylation

(2008) Andrew J. Young et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Analysis of the Concerted Metalation-Deprotonation Mechanism in Palladium-Catalyzed Direct Arylation Across a Broad Range of Aromatic Substrates

(2008) Serge I. Gorelsky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(OAc)2-catalyzed domino reactions of 1,2-dihaloarenes and 2-haloaryl arenesulfonates with Grignard reagents: efficient synthesis of substituted fluorenes

(2008) Cheng-Guo Dong et al.   TETRAHEDRON