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Title
Epigenetic Targeting of Glioblastoma
Authors
Keywords
-
Journal
Frontiers in Oncology
Volume 8, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-10-16
DOI
10.3389/fonc.2018.00448
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Note: Only part of the references are listed.- PARP Inhibitor Drugs in the Treatment of Breast, Ovarian, Prostate and Pancreatic Cancers: An Update of Clinical Trials
- (2018) Dalia Kamel et al. CURRENT DRUG TARGETS
- Targeting histone demethylases KDM5A and KDM5B in AML cancer cells: A comparative view
- (2018) Gelareh Shokri et al. LEUKEMIA RESEARCH
- DNA methylation-based classification of central nervous system tumours
- (2018) David Capper et al. NATURE
- WHO 2016 Classification of gliomas
- (2018) P. Wesseling et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02
- (2017) Evanthia Galanis et al. NEURO-ONCOLOGY
- Glioma epigenetics: From subclassification to novel treatment options
- (2017) Olga Gusyatiner et al. SEMINARS IN CANCER BIOLOGY
- AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
- (2017) Katharine Yen et al. Cancer Discovery
- Glioblastoma: new therapeutic strategies to address cellular and genomic complexity
- (2017) Xue Cai et al. Oncotarget
- Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells
- (2017) Barbara Banelli et al. Oncotarget
- Epigenetic therapy with inhibitors of histone methylation suppresses DNA damage signaling and increases glioma cell radiosensitivity
- (2017) Ozge Gursoy-Yuzugullu et al. Oncotarget
- The pharmacological role of histone demethylase JMJD3 inhibitor GSK-J4 on glioma cells
- (2017) Aixia Sui et al. Oncotarget
- Tumor suppression via inhibition of SWI/SNF complex-dependent NF-κB activation
- (2017) Kazuyoshi Kobayashi et al. Scientific Reports
- Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors
- (2017) Maithili P. Dalvi et al. Cell Reports
- The role of the SWI/SNF chromatin remodeling complex in maintaining the stemness of glioma initiating cells
- (2017) Hiroaki Hiramatsu et al. Scientific Reports
- Epigenetic dysregulation in neuroblastoma: A tale of miRNAs and DNA methylation
- (2016) Federica Parodi et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Mutations of Chromatin Structure Regulating Genes in Human Malignancies
- (2016) Jian Chen et al. CURRENT PROTEIN & PEPTIDE SCIENCE
- Targeted Therapeutics in Patients With High-Grade Gliomas: Past, Present, and Future
- (2016) Ricky Chen et al. CURRENT TREATMENT OPTIONS IN ONCOLOGY
- Targeting SWI/SNF mutant cancers with tyrosine kinase inhibitor therapy
- (2016) Paul H Huang Expert Review of Anticancer Therapy
- Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs
- (2016) Rohit Mathur et al. HAEMATOLOGICA
- Phase I trial of panobinostat and fractionated stereotactic re-irradiation therapy for recurrent high grade gliomas
- (2016) Wenyin Shi et al. JOURNAL OF NEURO-ONCOLOGY
- An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
- (2016) Maia Vinogradova et al. Nature Chemical Biology
- Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma
- (2016) Tara A. Barone et al. NEURO-ONCOLOGY
- Altered expression of miRNAs and methylation of their promoters are correlated in neuroblastoma
- (2016) Marco Maugeri et al. Oncotarget
- Inhibition of demethylase KDM6B sensitizes diffuse large B-cell lymphoma to chemotherapeutic drugs
- (2016) Rohit Mathur et al. HAEMATOLOGICA
- Chromatin remodelers: We are the drivers!!
- (2016) Monica Tyagi et al. Nucleus
- Chromatin remodelers: We are the drivers!!
- (2016) Monica Tyagi et al. Nucleus
- MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin
- (2015) Marco Gallo et al. CANCER CELL
- The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma
- (2015) Barbara Banelli et al. CELL CYCLE
- Deregulation of histone-modifying enzymes and chromatin structure modifiers contributes to glioma development
- (2015) Marta Maleszewska et al. Future Oncology
- A Phase 2 Study of Concurrent Radiation Therapy, Temozolomide, and the Histone Deacetylase Inhibitor Valproic Acid for Patients With Glioblastoma
- (2015) Andra V. Krauze et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Phase II study of panobinostat in combination with bevacizumab for recurrent glioblastoma and anaplastic glioma
- (2015) E. Q. Lee et al. NEURO-ONCOLOGY
- Epigenetic targets and drug discovery Part 2: Histone demethylation and DNA methylation
- (2015) Ke Liu et al. PHARMACOLOGY & THERAPEUTICS
- KDM1 is a novel therapeutic target for the treatment of gliomas
- (2015) Gangadhara R Sareddy et al. Oncotarget
- 5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft
- (2015) Alexandra Borodovsky et al. Oncotarget
- Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.
- (2015) Sevin Turcan et al. Oncotarget
- IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
- (2014) A. Kernytsky et al. BLOOD
- Molecular characterizations of glioblastoma, targeted therapy, and clinical results to date
- (2014) Jayson I. L. Bastien et al. CANCER
- Vulnerabilities of Mutant SWI/SNF Complexes in Cancer
- (2014) Katherine C. Helming et al. CANCER CELL
- Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
- (2014) Panagiotis Ntziachristos et al. NATURE
- A vaccine targeting mutant IDH1 induces antitumour immunity
- (2014) Theresa Schumacher et al. NATURE
- Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
- (2014) Rintaro Hashizume et al. NATURE MEDICINE
- Epigenetic modulation of the drug resistance genes MGMT, ABCB1 and ABCG2 in glioblastoma multiforme
- (2013) Moritz C Oberstadt et al. BMC CANCER
- Reduced H3K27me3 and DNA Hypomethylation Are Major Drivers of Gene Expression in K27M Mutant Pediatric High-Grade Gliomas
- (2013) Sebastian Bender et al. CANCER CELL
- Inhibition of PRC2 Activity by a Gain-of-Function H3 Mutation Found in Pediatric Glioblastoma
- (2013) P. W. Lewis et al. SCIENCE
- An Inhibitor of Mutant IDH1 Delays Growth and Promotes Differentiation of Glioma Cells
- (2013) D. Rohle et al. SCIENCE
- Targeted Inhibition of Mutant IDH2 in Leukemia Cells Induces Cellular Differentiation
- (2013) F. Wang et al. SCIENCE
- Nucleosome Remodeling and Epigenetics
- (2013) P. B. Becker et al. Cold Spring Harbor Perspectives in Biology
- O6-methylguanine DNA methyltransferase as a promising target for the treatment of temozolomide-resistant gliomas
- (2013) C-H Fan et al. Cell Death & Disease
- A small molecule modulates Jumonji histone demethylase activity and selectively inhibits cancer growth
- (2013) Lei Wang et al. Nature Communications
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- (2013) Lynn Bjerke et al. Cancer Discovery
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- (2012) G. J. Kitange et al. CLINICAL CANCER RESEARCH
- Epigenomics and Interindividual Differences in Drug Response
- (2012) M Ivanov et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The good, the bad and the ugly: Epigenetic mechanisms in glioblastoma
- (2012) Helena Carén et al. MOLECULAR ASPECTS OF MEDICINE
- IDH mutation impairs histone demethylation and results in a block to cell differentiation
- (2012) Chao Lu et al. NATURE
- IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
- (2012) Sevin Turcan et al. NATURE
- Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
- (2012) Jeremy Schwartzentruber et al. NATURE
- H3K4 demethylation by Jarid1a and Jarid1b contributes to retinoblastoma-mediated gene silencing during cellular senescence
- (2012) A. Chicas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours
- (2011) H A Tawbi et al. BRITISH JOURNAL OF CANCER
- Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
- (2011) Wei Xu et al. CANCER CELL
- Correlation of MGMT promoter methylation status with gene and protein expression levels in glioblastoma
- (2011) Miyuki Uno et al. Clinics
- CpG islands and the regulation of transcription
- (2011) A. M. Deaton et al. GENES & DEVELOPMENT
- The Histone Chaperone FACT: Structural Insights and Mechanisms for Nucleosome Reorganization
- (2011) Duane D. Winkler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phase II trial of vorinostat in combination with bortezomib in recurrent glioblastoma: a north central cancer treatment group study
- (2011) B. B. Friday et al. NEURO-ONCOLOGY
- A phase I/II trial of the histone deacetylase inhibitor romidepsin for adults with recurrent malignant glioma: North American Brain Tumor Consortium Study 03-03
- (2011) Fabio M. Iwamoto et al. NEURO-ONCOLOGY
- Identification of additional IDH mutations associated with oncometabolite R(−)-2-hydroxyglutarate production
- (2011) P S Ward et al. ONCOGENE
- Comprehensive Analysis of MGMT Promoter Methylation: Correlation with MGMT Expression and Clinical Response in GBM
- (2011) Nameeta Shah et al. PLoS One
- Drug-Tolerant Cancer Cells Show Reduced Tumor-Initiating Capacity: Depletion of CD44+ Cells and Evidence for Epigenetic Mechanisms
- (2011) Hong Yan et al. PLoS One
- Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
- (2010) Houtan Noushmehr et al. CANCER CELL
- Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
- (2010) Roel G.W. Verhaak et al. CANCER CELL
- A Chromatin-Mediated Reversible Drug-Tolerant State in Cancer Cell Subpopulations
- (2010) Sreenath V. Sharma et al. CELL
- A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
- (2010) Alexander Roesch et al. CELL
- Molecular and Enzymatic Profiles of Mammalian DNA Methyltransferases: Structures and Targets for Drugs
- (2010) F. Xu et al. CURRENT MEDICINAL CHEMISTRY
- The PARP Side of the Nucleus: Molecular Actions, Physiological Outcomes, and Clinical Targets
- (2010) Raga Krishnakumar et al. MOLECULAR CELL
- Histone variants — ancient wrap artists of the epigenome
- (2010) Paul B. Talbert et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A multi-institution phase II study of poly-ICLC and radiotherapy with concurrent and adjuvant temozolomide in adults with newly diagnosed glioblastoma
- (2010) M. R. Rosenfeld et al. NEURO-ONCOLOGY
- Phase II Trial of Temozolomide Plus O6-Benzylguanine in Adults With Recurrent, Temozolomide-Resistant Malignant Glioma
- (2009) Jennifer A. Quinn et al. JOURNAL OF CLINICAL ONCOLOGY
- Phase II Trial of Vorinostat in Recurrent Glioblastoma Multiforme: A North Central Cancer Treatment Group Study
- (2009) Evanthia Galanis et al. JOURNAL OF CLINICAL ONCOLOGY
- Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial
- (2009) Roger Stupp et al. LANCET ONCOLOGY
- Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma
- (2009) Jennifer A. Quinn et al. NEURO-ONCOLOGY
- IDH1andIDH2Mutations in Gliomas
- (2009) Hai Yan et al. NEW ENGLAND JOURNAL OF MEDICINE
- Methylation status of a single CpG site in theIL6promoter is related toIL6messenger RNA levels and rheumatoid arthritis
- (2008) Christoper J. Nile et al. ARTHRITIS AND RHEUMATISM
- Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
- (2008) P. A.C. Cloos et al. GENES & DEVELOPMENT
- Comprehensive genomic characterization defines human glioblastoma genes and core pathways
- (2008) Roger McLendon et al. NATURE
- An Integrated Genomic Analysis of Human Glioblastoma Multiforme
- (2008) D. W. Parsons et al. SCIENCE
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