IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
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Title
IDH2 mutation-induced histone and DNA hypermethylation is progressively reversed by small-molecule inhibition
Authors
Keywords
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Journal
BLOOD
Volume 125, Issue 2, Pages 296-303
Publisher
American Society of Hematology
Online
2014-11-15
DOI
10.1182/blood-2013-10-533604
References
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- Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation
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- Erratum: Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
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- Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
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