Anticancer drug candidate CBL0137, which inhibits histone chaperone FACT, is efficacious in preclinical orthotopic models of temozolomide-responsive and -resistant glioblastoma

Pharmacological Targeting of the Histone Chaperone Complex FACT Preferentially Eliminates Glioblastoma Stem Cells and Prolongs Survival in Preclinical Models

(2016) Josephine Kam Tai Dermawan et al.   CANCER RESEARCH

Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors

(2015) Encouse B. Golden et al.   Neurosurgical Focus

Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells

(2015) Henry Garcia et al.   Oncotarget

Curaxin CBL0137 eradicates drug resistant cancer stem cells and potentiates efficacy of gemcitabine in preclinical models of pancreatic cancer

(2015) Catherine Burkhart et al.   Oncotarget

Bex2 Controls Proliferation of Human Glioblastoma Cells Through NF-κB Signaling Pathway

(2014) Qingming Meng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007-2011

(2014) Q. T. Ostrom et al.   NEURO-ONCOLOGY

Emerging Insights into Barriers to Effective Brain Tumor Therapeutics

(2014) Graeme F. Woodworth et al.   Frontiers in Oncology

Saponin 1 Induces Apoptosis and Suppresses NF-κB-Mediated Survival Signaling in Glioblastoma Multiforme (GBM)

(2013) Juan Li et al.   PLoS One

Current understanding of the role and targeting of tumor suppressor p53 in glioblastoma multiforme

(2013) Bryant England et al.   TUMOR BIOLOGY

Facilitates Chromatin Transcription Complex Is an “Accelerator” of Tumor Transformation and Potential Marker and Target of Aggressive Cancers

(2013) Henry Garcia et al.   Cell Reports

Targeting FACT Complex Suppresses Mammary Tumorigenesis in Her2/neu Transgenic Mice

(2012) I. E. Koman et al.   Cancer Prevention Research

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL