Innate Lymphocytes in Adipose Tissue Homeostasis and Their Alterations in Obesity and Colorectal Cancer

Mucosa-associated invariant T cells in malignancies: a faithful friend or formidable foe?

(2018) S. M. Mansour Haeryfar et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Unconventional T Cell Targets for Cancer Immunotherapy

(2018) Dale I. Godfrey et al.   IMMUNITY

Impaired natural killer cell subset phenotypes in human obesity

(2018) Ina Bähr et al.   IMMUNOLOGIC RESEARCH

Heterogeneity of adipose tissue in development and metabolic function

(2018) Theresa Schoettl et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Tissue-Specific Phenotype and Activation of iNKT Cells in Morbidly Obese Subjects: Interaction with Adipocytes and Effect of Bariatric Surgery

(2018) Soledad López et al.   OBESITY SURGERY

Diagnostic value of peripheral blood immune profiling in colorectal cancer

(2018) Joungbum Choi et al.   Annals of Surgical Treatment and Research

Molecular Determinants of Target Cell Recognition by Human γδ T Cells

(2018) André E. Simões et al.   Frontiers in Immunology

Association Between Natural Killer Cell Activity and Colorectal Cancer in High-Risk Subjects Undergoing Colonoscopy

(2017) Gilles Jobin et al.   GASTROENTEROLOGY

Dissecting human ILC heterogeneity: more than just three subsets

(2017) Yannick Simoni et al.   IMMUNOLOGY

Lipodystrophy and obesity are associated with decreased number of T cells with regulatory function and pro-inflammatory macrophage phenotype

(2017) S Berger et al.   INTERNATIONAL JOURNAL OF OBESITY

Natural Killer Cells from the Subcutaneous Adipose Tissue Underexpress the NKp30 and NKp44 in Obese Persons and Are Less Active against Major Histocompatibility Complex Class I Non-Expressing Neoplastic Cells

(2017) Alireza Shoae-Hassani et al.   Frontiers in Immunology

Distinct Blood and Visceral Adipose Tissue Regulatory T Cell and Innate Lymphocyte Profiles Characterize Obesity and Colorectal Cancer

(2017) Gloria Donninelli et al.   Frontiers in Immunology

Innate Lymphoid Cells in Intestinal Inflammation

(2017) Alessandra Geremia et al.   Frontiers in Immunology

Obesity, Inflammation, and Cancer

(2016) Tuo Deng et al.   Annual Review of Pathology-Mechanisms of Disease

Hallmarks of Tissue-Resident Lymphocytes

(2016) Xiying Fan et al.   CELL

Effect of Adipocyte Secretome in Melanoma Progression and Vasculogenic Mimicry

(2016) Pedro Coelho et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The microenvironment of visceral adipose tissue and liver alter natural killer cell viability and function

(2016) Melissa J. Conroy et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Visceral fat adipocytes from obese and colorectal cancer subjects exhibit distinct secretory and ω6 polyunsaturated fatty acid profiles and deliver immunosuppressive signals to innate immunity cells

(2016) Manuela Del Cornò et al.   Oncotarget

Clinical relevance of circulating mucosal-associated invariant T cell levels and their anti-cancer activity in patients with mucosal-associated cancer

(2016) Eun Jeong Won et al.   Oncotarget

Circulating and tumor-infiltrating mucosal associated invariant T (MAIT) cells in colorectal cancer patients

(2016) Limian Ling et al.   Scientific Reports

Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer

(2015) S. Amor et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Azathioprine therapy selectively ablates human Vδ2+ T cells in Crohn’s disease

(2015) Neil E. McCarthy et al.   JOURNAL OF CLINICAL INVESTIGATION

Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients

(2015) Isabelle Magalhaes et al.   JOURNAL OF CLINICAL INVESTIGATION

Altered Distribution and Increased IL-17 Production by Mucosal-Associated Invariant T Cells in Adult and Childhood Obesity

(2015) Eirin Carolan et al.   JOURNAL OF IMMUNOLOGY

Obesity-associated cancer: an immunological perspective

(2015) Melissa J. Conroy et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

iNKT and MAIT Cell Alterations in Diabetes

(2015) Isabelle Magalhaes et al.   Frontiers in Immunology

Obesity Impairs γδ T Cell Homeostasis and Antiviral Function in Humans

(2015) Anne E. Costanzo et al.   PLoS One

Adipose invariant natural killer T cells

(2014) Lydia Lynch   IMMUNOLOGY

The role of adipose tissue immune cells in obesity and low-grade inflammation

(2014) Milos Mraz et al.   JOURNAL OF ENDOCRINOLOGY

Crosstalk between Adipocytes and Immune Cells in Adipose Tissue Inflammation and Metabolic Dysregulation in Obesity

(2014) Jin Young Huh et al.   MOLECULES AND CELLS

Group 2 innate lymphoid cells promote beiging of white adipose tissue and limit obesity

(2014) Jonathan R. Brestoff et al.   NATURE

Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance

(2013) Byung-Cheol Lee et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Adipocyte-derived lipids modulate CD4+T-cell function

(2013) Andreea Ioan-Facsinay et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Impact of Childhood Obesity on Inflammation, Innate Immune Cell Frequency, and Metabolic MicroRNA Expression

(2013) Eirin Carolan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Adipocytes Modulate the Phenotype of Human Macrophages through Secreted Lipids

(2013) I. R. Klein-Wieringa et al.   JOURNAL OF IMMUNOLOGY

Adipose tissue NK cells manifest an activated phenotype in human obesity

(2013) Robert W. O’Rourke et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Secreted Human Adipose Leptin Decreases Mitochondrial Respiration in HCT116 Colon Cancer Cells

(2013) Einav Yehuda-Shnaidman et al.   PLoS One

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

(2012) Lydia Lynch et al.   IMMUNITY

Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity

(2012) Yewei Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural killer T cells in adipose tissue prevent insulin resistance

(2012) Henk S. Schipper et al.   JOURNAL OF CLINICAL INVESTIGATION

A Novel Function of Adipocytes in Lipid Antigen Presentation to iNKT Cells

(2012) J. Y. Huh et al.   MOLECULAR AND CELLULAR BIOLOGY

Adipose tissue-resident immune cells: key players in immunometabolism

(2012) Henk S. Schipper et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue

(2011) J. Lysaght et al.   CANCER LETTERS

Low Levels of Lipogenic Enzymes in Peritumoral Adipose Tissue of Colorectal Cancer Patients

(2011) Maria Notarnicola et al.   LIPIDS

Adipose tissue recruitment of leukocytes

(2010) Emily K Anderson et al.   CURRENT OPINION IN LIPIDOLOGY

Up-regulation of the novel proinflammatory adipokines lipocalin-2, chitinase-3 like-1 and osteopontin as well as angiogenic-related factors in visceral adipose tissue of patients with colon cancer

(2010) Victoria Catalán et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Association of Inflammation-Related and microRNA Gene Expression with Cancer-Specific Mortality of Colon Adenocarcinoma

(2009) A. J. Schetter et al.   CLINICAL CANCER RESEARCH

Invariant NKT cells and CD1d+cells amass in human omentum and are depleted in patients with cancer and obesity

(2009) Lydia Lynch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Are Natural Killer Cells Protecting the Metabolically Healthy Obese Patient?

(2009) Lydia A. Lynch et al.   Obesity

Decreased risk of colorectal cancer with the high natural killer cell activity NKG2D genotype in Japanese

(2008) Hiroki Furue et al.   CARCINOGENESIS