Adipose invariant natural killer T cells

Cutting Edge: IL-25 Elicits Innate Lymphoid Type 2 and Type II NKT Cells That Regulate Obesity in Mice

(2013) E. Hams et al.   JOURNAL OF IMMUNOLOGY

Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity

(2013) Lee A Albacker et al.   NATURE MEDICINE

Adipose Tissue Invariant NKT Cells Protect against Diet-Induced Obesity and Metabolic Disorder through Regulatory Cytokine Production

(2012) Lydia Lynch et al.   IMMUNITY

Lipid-Antigen Presentation by CD1d+ B Cells Is Essential for the Maintenance of Invariant Natural Killer T Cells

(2012) Anneleen Bosma et al.   IMMUNITY

Activation of Natural Killer T Cells Promotes M2 Macrophage Polarization in Adipose Tissue and Improves Systemic Glucose Tolerance via Interleukin-4 (IL-4)/STAT6 Protein Signaling Axis in Obesity

(2012) Yewei Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Short Term High Fat Diet Challenge Promotes Alternative Macrophage Polarization in Adipose Tissue via Natural Killer T Cells and Interleukin-4

(2012) Yewei Ji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Natural killer T cells in adipose tissue prevent insulin resistance

(2012) Henk S. Schipper et al.   JOURNAL OF CLINICAL INVESTIGATION

A Novel Function of Adipocytes in Lipid Antigen Presentation to iNKT Cells

(2012) J. Y. Huh et al.   MOLECULAR AND CELLULAR BIOLOGY

Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus

(2012) Federica Facciotti et al.   NATURE IMMUNOLOGY

Lower TCR repertoire diversity in Traj18-deficient mice

(2012) Romain Bedel et al.   NATURE IMMUNOLOGY

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

(2012) Saswata Talukdar et al.   NATURE MEDICINE

Activation of invariant natural killer T cells by lipid excess promotes tissue inflammation, insulin resistance, and hepatic steatosis in obese mice

(2012) L. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microbial Exposure During Early Life Has Persistent Effects on Natural Killer T Cell Function

(2012) T. Olszak et al.   SCIENCE

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

Adipose tissue-resident immune cells: key players in immunometabolism

(2012) Henk S. Schipper et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Development and Function of Invariant Natural Killer T Cells Producing TH2- and TH17-Cytokines

(2012) Hiroshi Watarai et al.   PLOS BIOLOGY

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection

(2011) Manfred Brigl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

PLZF induces an intravascular surveillance program mediated by long-lived LFA-1–ICAM-1 interactions

(2011) Seddon Y. Thomas et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals

(2011) Patrick J Brennan et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

(2011) Yuki Kinjo et al.   NATURE IMMUNOLOGY

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

(2011) Daniel A Winer et al.   NATURE MEDICINE

Mice Lacking NKT Cells but with a Complete Complement of CD8+ T-Cells Are Not Protected against the Metabolic Abnormalities of Diet-Induced Obesity

(2011) Benjamin S. Mantell et al.   PLoS One

Impact of CD1d Deficiency on Metabolism

(2011) Maya E. Kotas et al.   PLoS One

Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis

(2011) D. Wu et al.   SCIENCE

Natural Killer T Cells Are Involved in Adipose Tissues Inflammation and Glucose Intolerance in Diet-Induced Obese Mice

(2009) Kazue Ohmura et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Invariant NKT cells and CD1d+cells amass in human omentum and are depleted in patients with cancer and obesity

(2009) Lydia Lynch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

(2009) Markus Feuerer et al.   NATURE MEDICINE

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

(2009) Satoshi Nishimura et al.   NATURE MEDICINE

Normalization of obesity-associated insulin resistance through immunotherapy

(2009) Shawn Winer et al.   NATURE MEDICINE

Recognition of Lyso-Phospholipids by Human Natural Killer T Lymphocytes

(2009) Lisa M. Fox et al.   PLOS BIOLOGY

Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes

(2008) C. N. Lumeng et al.   DIABETES

The Transcription Factor PLZF Directs the Effector Program of the NKT Cell Lineage

(2008) Adam K. Savage et al.   IMMUNITY

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity

(2008) Asuka Terashima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells

(2008) Xiong Ma et al.   JOURNAL OF HEPATOLOGY

The BTB–zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

(2008) Damian Kovalovsky et al.   NATURE IMMUNOLOGY

NK T cells provide lipid antigen-specific cognate help for B cells

(2008) E. A. Leadbetter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA