Dissecting human ILC heterogeneity: more than just three subsets

Human Group 1 Innate Lymphocytes Are Negative for Surface CD3ε but Express CD5

(2017) Florence Roan et al.   IMMUNITY

Human Innate Lymphoid Cell Subsets Possess Tissue-Type Based Heterogeneity in Phenotype and Frequency

(2017) Yannick Simoni et al.   IMMUNITY

How Many Subsets of Innate Lymphoid Cells Do We Need?

(2017) Kafi N. Ealey et al.   IMMUNITY

Human ILC1: To Be or Not to Be

(2017) Jochem H. Bernink et al.   IMMUNITY

Toward Meaningful Definitions of Innate-Lymphoid-Cell Subsets

(2017) Yannick Simoni et al.   IMMUNITY

Are ILC2s Jekyll and Hyde in airway inflammation?

(2017) Kafi N. Ealey et al.   IMMUNOLOGICAL REVIEWS

A phenotypically and functionally distinct human T H 2 cell subpopulation is associated with allergic disorders

(2017) Erik Wambre et al.   Science Translational Medicine

Neuropilin-1 Is Expressed on Lymphoid Tissue Residing LTi-like Group 3 Innate Lymphoid Cells and Associated with Ectopic Lymphoid Aggregates

(2017) Medya Mara Shikhagaie et al.   Cell Reports

Compartment-specific distribution of human intestinal innate lymphoid cells is altered in HIV patients under effective therapy

(2017) Benjamin Krämer et al.   PLoS Pathogens

A novel IL-10-producing innate lymphoid cells (ILC10) in a contact hypersensitivity mouse model

(2016) Hyuk Soon Kim et al.   BMB Reports

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

(2016) Meital Gury-BenAri et al.   CELL

Differentiation of human innate lymphoid cells (ILCs)

(2016) Kerstin Juelke et al.   CURRENT OPINION IN IMMUNOLOGY

A Progenitor Cell Expressing Transcription Factor RORγt Generates All Human Innate Lymphoid Cell Subsets

(2016) Steven D. Scoville et al.   IMMUNITY

Innate Lymphoid Cells Are Depleted Irreversibly during Acute HIV-1 Infection in the Absence of Viral Suppression

(2016) Henrik N. Kløverpris et al.   IMMUNITY

IL-12 drives functional plasticity of human group 2 innate lymphoid cells

(2016) Ai Ing Lim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CD4+Group 1 Innate Lymphoid Cells (ILC) Form a Functionally Distinct ILC Subset That Is Increased in Systemic Sclerosis

(2016) Florence Roan et al.   JOURNAL OF IMMUNOLOGY

Mass cytometry: blessed with the curse of dimensionality

(2016) Evan W Newell et al.   NATURE IMMUNOLOGY

The heterogeneity of human CD127+ innate lymphoid cells revealed by single-cell RNA sequencing

(2016) Åsa K Björklund et al.   NATURE IMMUNOLOGY

Evidence of innate lymphoid cell redundancy in humans

(2016) Frédéric Vély et al.   NATURE IMMUNOLOGY

IL-1 is a critical regulator of group 2 innate lymphoid cell function and plasticity

(2016) Yoichiro Ohne et al.   NATURE IMMUNOLOGY

IL-1β, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs

(2016) Suzanne M Bal et al.   NATURE IMMUNOLOGY

Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

(2016) Jonathan S Silver et al.   NATURE IMMUNOLOGY

Transient inhibition of ROR-γt therapeutically limits intestinal inflammation by reducing TH17 cells and preserving group 3 innate lymphoid cells

(2016) David R Withers et al.   NATURE MEDICINE

ILC3 GM-CSF production and mobilisation orchestrate acute intestinal inflammation

(2016) Claire Pearson et al.   eLife

CXCR6 marks a novel subset of T-betloEomeshi natural killer cells residing in human liver

(2016) Kerstin A. Stegmann et al.   Scientific Reports

ICOS regulates the pool of group 2 innate lymphoid cells under homeostatic and inflammatory conditions in mice

(2015) Daniela Paclik et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Identification of a Human Natural Killer Cell Lineage-Restricted Progenitor in Fetal and Adult Tissues

(2015) Virginie M. Renoux et al.   IMMUNITY

Interleukin-12 and -23 Control Plasticity of CD127+ Group 1 and Group 3 Innate Lymphoid Cells in the Intestinal Lamina Propria

(2015) Jochem H. Bernink et al.   IMMUNITY

ICOS:ICOS-Ligand Interaction Is Required for Type 2 Innate Lymphoid Cell Function, Homeostasis, and Induction of Airway Hyperreactivity

(2015) Hadi Maazi et al.   IMMUNITY

Group 2 Innate Lymphoid Cells Express Functional NKp30 Receptor Inducing Type 2 Cytokine Production

(2015) Maryam Salimi et al.   JOURNAL OF IMMUNOLOGY

The biology of innate lymphoid cells

(2015) David Artis et al.   NATURE

IL-6 as a keystone cytokine in health and disease

(2015) Christopher A Hunter et al.   NATURE IMMUNOLOGY

Group 3 innate lymphoid cells continuously require the transcription factor GATA-3 after commitment

(2015) Chao Zhong et al.   NATURE IMMUNOLOGY

Targeting GM-CSF in inflammatory diseases

(2015) Ian P. Wicks et al.   Nature Reviews Rheumatology

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4+ T cells

(2015) M. R. Hepworth et al.   SCIENCE

Versatile functions for IL-6 in metabolism and cancer

(2015) Jan Mauer et al.   TRENDS IN IMMUNOLOGY

NCR+ILC3 concentrate in human lung cancer and associate with intratumoral lymphoid structures

(2015) Paolo Carrega et al.   Nature Communications

Human innate lymphoid cells

(2014) M. D. Hazenberg et al.   BLOOD

Human RORγt+CD34+ Cells Are Lineage-Specified Progenitors of Group 3 RORγt+ Innate Lymphoid Cells

(2014) Elisa Montaldo et al.   IMMUNITY

Innate Lymphoid Cells in Inflammation and Immunity

(2014) Andrew N.J. McKenzie et al.   IMMUNITY

Development, Differentiation, and Diversity of Innate Lymphoid Cells

(2014) Andreas Diefenbach et al.   IMMUNITY

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells

(2014) Luzheng Xue et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

CD56brightPerforinlow Noncytotoxic Human NK Cells Are Abundant in Both Healthy and Neoplastic Solid Tissues and Recirculate to Secondary Lymphoid Organs via Afferent Lymph

(2014) P. Carrega et al.   JOURNAL OF IMMUNOLOGY

Identification of diverse innate lymphoid cells in human decidua

(2014) P Vacca et al.   Mucosal Immunology

CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages

(2014) Joannah R. Fergusson et al.   Cell Reports

Recognition Strategies of Group 3 Innate Lymphoid Cells

(2014) Monica Killig et al.   Frontiers in Immunology

Human NK cell receptors/markers: A tool to analyze NK cell development, subsets and function

(2013) Elisa Montaldo et al.   CYTOMETRY PART A

RORγt+ Innate Lymphoid Cells Acquire a Proinflammatory Program upon Engagement of the Activating Receptor NKp44

(2013) Timor Glatzer et al.   IMMUNITY

Intraepithelial Type 1 Innate Lymphoid Cells Are a Unique Subset of IL-12- and IL-15-Responsive IFN-γ-Producing Cells

(2013) Anja Fuchs et al.   IMMUNITY

A role for IL-25 and IL-33–driven type-2 innate lymphoid cells in atopic dermatitis

(2013) Maryam Salimi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human CD4+CD3- Innate-Like T Cells Provide a Source of TNF and Lymphotoxin-   and Are Elevated in Rheumatoid Arthritis

(2013) V. Bekiaris et al.   JOURNAL OF IMMUNOLOGY

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

(2013) Matthew R. Hepworth et al.   NATURE

Human type 1 innate lymphoid cells accumulate in inflamed mucosal tissues

(2013) Jochem H Bernink et al.   NATURE IMMUNOLOGY

Natural Cytotoxicity Receptors: Broader Expression Patterns and Functions in Innate and Adaptive Immune Cells

(2013) Kelly Hudspeth et al.   Frontiers in Immunology

Interleukin-18 and IL-18 Binding Protein

(2013) Charles A. Dinarello et al.   Frontiers in Immunology

The Transcription Factor GATA3 Is Essential for the Function of Human Type 2 Innate Lymphoid Cells

(2012) Jenny Mjösberg et al.   IMMUNITY

Interleukin-6: from an inflammatory marker to a target for inflammatory diseases

(2012) Mercedes Rincon   TRENDS IN IMMUNOLOGY

Functional Differences between Human NKp44− and NKp44+ RORC+ Innate Lymphoid Cells

(2012) Kerim Hoorweg et al.   Frontiers in Immunology

Role of the Aryl Hydrocarbon Receptor in Controlling Maintenance and Functional Programs of RORγt+ Innate Lymphoid Cells and Intraepithelial Lymphocytes

(2012) Elina A. Kiss et al.   Frontiers in Immunology

Induction of Lectin-like Transcript 1 (LLT1) Protein Cell Surface Expression by Pathogens and Interferon-γ Contributes to Modulate Immune Responses

(2011) Claire Germain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

Expansion of human NK-22 cells with IL-7, IL-2, and IL-1  reveals intrinsic functional plasticity

(2010) M. Cella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-  on activation

(2010) A. De Maria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of human NK-cell cytokine and chemokine production by target cell recognition

(2009) C. Fauriat et al.   BLOOD

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Microbial Flora Drives Interleukin 22 Production in Intestinal NKp46+ Cells that Provide Innate Mucosal Immune Defense

(2008) Naoko Satoh-Takayama et al.   IMMUNITY

CD56brightnatural killer (NK) cells: an important NK cell subset

(2008) Aurélie Poli et al.   IMMUNOLOGY

A human natural killer cell subset provides an innate source of IL-22 for mucosal immunity

(2008) Marina Cella et al.   NATURE

Human fetal lymphoid tissue–inducer cells are interleukin 17–producing precursors to RORC+ CD127+ natural killer–like cells

(2008) Tom Cupedo et al.   NATURE IMMUNOLOGY