Interplay Between the Unfolded Protein Response and Immune Function in the Development of Neurodegenerative Diseases
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Title
Interplay Between the Unfolded Protein Response and Immune Function in the Development of Neurodegenerative Diseases
Authors
Keywords
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Journal
Frontiers in Immunology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-11-02
DOI
10.3389/fimmu.2018.02541
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Related references
Note: Only part of the references are listed.- Innate Immunity and Neurodegeneration
- (2018) Larisa I. Labzin et al. Annual Review of Medicine
- Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration
- (2018) Aleksandra Deczkowska et al. CELL
- Antigen presentation unfolded: identifying convergence points between the UPR and antigen presentation pathways
- (2018) Fabiola Osorio et al. CURRENT OPINION IN IMMUNOLOGY
- The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway
- (2018) Daniel Hughes et al. FEBS Journal
- High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease
- (2018) Dunja Mrdjen et al. IMMUNITY
- The role of immune cells in brain development and neurodevelopmental diseases
- (2018) Shogo Tanabe et al. INTERNATIONAL IMMUNOLOGY
- The Unfolded Protein Response and Cell Fate Control
- (2018) Claudio Hetz et al. MOLECULAR CELL
- Gene Therapy Strategies to Restore ER Proteostasis in Disease
- (2018) Vicente Valenzuela et al. MOLECULAR THERAPY
- Targeting PERK signaling with the small molecule GSK2606414 prevents neurodegeneration in a model of Parkinson's disease
- (2018) Gabriela Mercado et al. NEUROBIOLOGY OF DISEASE
- ER Proteostasis Control of Neuronal Physiology and Synaptic Function
- (2018) Gabriela Martínez et al. TRENDS IN NEUROSCIENCES
- Endoplasmic reticulum stress leads to accumulation of wild-type SOD1 aggregates associated with sporadic amyotrophic lateral sclerosis
- (2018) Danilo B. Medinas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteostasis disturbance in amyotrophic lateral sclerosis
- (2017) Danilo B. Medinas et al. HUMAN MOLECULAR GENETICS
- Myeloid Cells in the Central Nervous System
- (2017) Jasmin Herz et al. IMMUNITY
- The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
- (2017) Susanne Krasemann et al. IMMUNITY
- Fine-tuning PERK signaling for neuroprotection
- (2017) Mark Halliday et al. JOURNAL OF NEUROCHEMISTRY
- Neuronal activity-dependent local activation of dendritic unfolded protein response promotes expression of brain-derived neurotrophic factor in cell soma
- (2017) Atsushi Saito et al. JOURNAL OF NEUROCHEMISTRY
- T cells from patients with Parkinson’s disease recognize α-synuclein peptides
- (2017) David Sulzer et al. NATURE
- Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival
- (2017) Simon J. Tavernier et al. NATURE CELL BIOLOGY
- ER stress and the unfolded protein response in neurodegeneration
- (2017) Claudio Hetz et al. Nature Reviews Neurology
- Potential importance of B cells in aging and aging-associated neurodegenerative diseases
- (2017) Arya Biragyn et al. Seminars in Immunopathology
- Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration
- (2017) Duraisamy Kempuraj et al. Frontiers in Cellular Neuroscience
- PDI is an essential redox-sensitive activator of PERK during the unfolded protein response (UPR)
- (2017) Philip Kranz et al. Cell Death & Disease
- The Endoplasmic Reticulum Unfolded Protein Response in Neurodegenerative Disorders and Its Potential Therapeutic Significance
- (2017) Paolo Remondelli et al. Frontiers in Molecular Neuroscience
- The unfolded protein response: mechanisms and therapy of neurodegeneration
- (2016) Heather L. Smith et al. BRAIN
- Linking T cells to Alzheimer's disease: from neurodegeneration to neurorepair
- (2016) Karen J Bryson et al. CURRENT OPINION IN PHARMACOLOGY
- Attenuation of PKR-like ER Kinase (PERK) Signaling Selectively Controls Endoplasmic Reticulum Stress-induced Inflammation Without Compromising Immunological Responses
- (2016) Lauren N. Guthrie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Atf6αdeficiency suppresses microglial activation and ameliorates pathology of experimental autoimmune encephalomyelitis
- (2016) Hieu Minh Ta et al. JOURNAL OF NEUROCHEMISTRY
- The transcription factor XBP1s restores hippocampal synaptic plasticity and memory by control of the Kalirin-7 pathway in Alzheimer model
- (2016) M Cissé et al. MOLECULAR PSYCHIATRY
- Origin, fate and dynamics of macrophages at central nervous system interfaces
- (2016) Tobias Goldmann et al. NATURE IMMUNOLOGY
- Understanding the Role of T Cells in CNS Homeostasis
- (2016) Erik Ellwardt et al. TRENDS IN IMMUNOLOGY
- Emerging Roles for the Unfolded Protein Response in the Developing Nervous System
- (2016) Juliette D. Godin et al. TRENDS IN NEUROSCIENCES
- Schlafen2 mutation unravels a role for chronic ER stress in the loss of T cell quiescence
- (2016) Ibrahim Omar et al. Oncotarget
- Regulation of Memory Formation by the Transcription Factor XBP1
- (2016) Gabriela Martínez et al. Cell Reports
- Activation of the unfolded protein response promotes axonal regeneration after peripheral nerve injury
- (2016) Maritza Oñate et al. Scientific Reports
- The unfolded protein response in neurodegenerative diseases: a neuropathological perspective
- (2015) Wiep Scheper et al. ACTA NEUROPATHOLOGICA
- The Role of Endoplasmic Reticulum Stress in Human Pathology
- (2015) Scott A. Oakes et al. Annual Review of Pathology-Mechanisms of Disease
- Endoplasmic Reticulum Stress–Induced IRE1α Activation Mediates Cross-Talk of GSK-3β and XBP-1 To Regulate Inflammatory Cytokine Production
- (2015) Sena Kim et al. JOURNAL OF IMMUNOLOGY
- Erratum: Proteostasis control by the unfolded protein response
- (2015) Claudio Hetz et al. NATURE CELL BIOLOGY
- Immune attack: the role of inflammation in Alzheimer disease
- (2015) Frank L. Heppner et al. NATURE REVIEWS NEUROSCIENCE
- Neuromodulatory properties of inflammatory cytokines and their impact on neuronal excitability
- (2015) Annamaria Vezzani et al. NEUROPHARMACOLOGY
- Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease
- (2015) Michael Phillip Kurnellas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Myeloid Dendritic Cells are Potential Players in Human Neurodegenerative Diseases
- (2015) Paola Bossù et al. Frontiers in Immunology
- Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
- (2014) Masanori Matsumoto et al. IMMUNITY
- Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity
- (2014) Ilaria Bellezza et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Endoplasmic Reticulum Stress Regulator XBP-1 Contributes to Effector CD8+ T Cell Differentiation during Acute Infection
- (2014) D. Kamimura et al. JOURNAL OF IMMUNOLOGY
- T-cell-mediated regulation of neuroinflammation involved in neurodegenerative diseases
- (2014) Hugo González et al. Journal of Neuroinflammation
- PERK-Dependent Activation of JAK1 and STAT3 Contributes to Endoplasmic Reticulum Stress-Induced Inflammation
- (2014) G. P. Meares et al. MOLECULAR AND CELLULAR BIOLOGY
- The unfolded-protein-response sensor IRE-1α regulates the function of CD8α+ dendritic cells
- (2014) Fabiola Osorio et al. NATURE IMMUNOLOGY
- Systemic stress signalling: understanding the cell non-autonomous control of proteostasis
- (2014) Rebecca C. Taylor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases
- (2014) Claudio Hetz et al. NATURE REVIEWS NEUROSCIENCE
- Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1
- (2014) P. Valdes et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia
- (2014) B. Kharabi Masouleh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Getting RIDD of RNA: IRE1 in cell fate regulation
- (2014) M. Maurel et al. TRENDS IN BIOCHEMICAL SCIENCES
- New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease
- (2014) James P. Fuller et al. Frontiers in Neuroscience
- Physiological roles of regulated Ire1 dependent decay
- (2014) Dina S. Coelho et al. Frontiers in Genetics
- T helper-17 activation dominates the immunologic milieu of both amyotrophic lateral sclerosis and progressive multiple sclerosis
- (2013) Marina Saresella et al. CLINICAL IMMUNOLOGY
- Self-antigen-Driven Activation Induces Instability of Regulatory T Cells during an Inflammatory Autoimmune Response
- (2013) Samantha L. Bailey-Bucktrout et al. IMMUNITY
- The Serine-threonine Kinase Inositol-requiring Enzyme 1α (IRE1α) Promotes IL-4 Production in T Helper Cells
- (2013) Kyeorda L. Kemp et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- How Do Immune Cells Support and Shape the Brain in Health, Disease, and Aging?
- (2013) M. Schwartz et al. JOURNAL OF NEUROSCIENCE
- Intracranial Injection of Gammagard, a Human IVIg, Modulates the Inflammatory Response of the Brain and Lowers A in APP/PS1 Mice Along a Different Time Course than Anti-A Antibodies
- (2013) T. L. Sudduth et al. JOURNAL OF NEUROSCIENCE
- Suppression of eIF2α kinases alleviates Alzheimer's disease–related plasticity and memory deficits
- (2013) Tao Ma et al. NATURE NEUROSCIENCE
- Functional Contribution of the Transcription Factor ATF4 to the Pathogenesis of Amyotrophic Lateral Sclerosis
- (2013) Soledad Matus et al. PLoS One
- Microglia: Scapegoat, Saboteur, or Something Else?
- (2013) A. Aguzzi et al. SCIENCE
- Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice
- (2013) J. A. Moreno et al. Science Translational Medicine
- Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson disease
- (2013) Carmen Noelker et al. Scientific Reports
- ER stress upregulated PGE2/IFNγ-induced IL-6 expression and down-regulated iNOS expression in glial cells
- (2013) Toru Hosoi et al. Scientific Reports
- Stress-Independent Activation of XBP1s and/or ATF6 Reveals Three Functionally Diverse ER Proteostasis Environments
- (2013) Matthew D. Shoulders et al. Cell Reports
- AAV-mediated delivery of the transcription factor XBP1s into the striatum reduces mutant Huntingtin aggregation in a mouse model of Huntington’s disease
- (2012) Amparo Zuleta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress
- (2012) Alana G. Lerner et al. Cell Metabolism
- Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase expression by endoplasmic reticulum stress
- (2012) Hui-Ju Ho et al. CELLULAR SIGNALLING
- Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
- (2012) Rene L. Vidal et al. HUMAN MOLECULAR GENETICS
- NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
- (2012) Michael T. Heneka et al. NATURE
- ATF6alpha Promotes Astroglial Activation and Neuronal Survival in a Chronic Mouse Model of Parkinson’s Disease
- (2012) Koji Hashida et al. PLoS One
- ER Stress Activates NF-κB by Integrating Functions of Basal IKK Activity, IRE1 and PERK
- (2012) Arvin B. Tam et al. PLoS One
- Activation of the unfolded protein response enhances motor recovery after spinal cord injury
- (2012) V Valenzuela et al. Cell Death & Disease
- Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
- (2011) Niroshana Anandasabapathy et al. JOURNAL OF EXPERIMENTAL MEDICINE
- ER stress response plays an important role in aggregation of α-synuclein
- (2011) Peizhou Jiang et al. Molecular Neurodegeneration
- The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
- (2011) P. Walter et al. SCIENCE
- The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death
- (2010) Naohiro Egawa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages
- (2010) Fabio Martinon et al. NATURE IMMUNOLOGY
- Impaired ATF6α processing, decreased Rheb and neuronal cell cycle re-entry in Huntington's disease
- (2010) Maria Rosario Fernandez-Fernandez et al. NEUROBIOLOGY OF DISEASE
- Activation of PERK Signaling Attenuates Aβ-Mediated ER Stress
- (2010) Do Yeon Lee et al. PLoS One
- XBP-1 regulates signal transduction, transcription factors and bone marrow colonization in B cells
- (2009) Chih-Chi Andrew Hu et al. EMBO JOURNAL
- XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy
- (2009) C. Hetz et al. GENES & DEVELOPMENT
- Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
- (2009) Claudio Hetz et al. MOLECULAR CELL
- CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
- (2009) Cameron R Stewart et al. NATURE IMMUNOLOGY
- Attenuated BDNF-induced upregulation of GABAergic markers in neurons lacking Xbp1
- (2008) Akiko Hayashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Protective effect against Parkinson's disease-related insults through the activation of XBP1
- (2008) Megumi Sado et al. BRAIN RESEARCH
- B- and T-cell Development Both Involve Activity of the Unfolded Protein Response Pathway
- (2008) Ryan Brunsing et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Infiltration of CD4+ lymphocytes into the brain contributes to neurodegeneration in a mouse model of Parkinson disease
- (2008) Vanessa Brochard et al. JOURNAL OF CLINICAL INVESTIGATION
- Origin and physiological roles of inflammation
- (2008) Ruslan Medzhitov NATURE
- Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis
- (2008) Julie D. Atkin et al. NEUROBIOLOGY OF DISEASE
- Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis
- (2008) C. Hetz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
- The unfolded protein response of B-lymphocytes: PERK-independent development of antibody-secreting cells
- (2007) Jennifer N. Gass et al. MOLECULAR IMMUNOLOGY
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