The Adhesion G Protein-Coupled Receptor GPR97/ADGRG3 Is Expressed in Human Granulocytes and Triggers Antimicrobial Effector Functions

Adhesion G Protein–Coupled Receptors as Drug Targets

(2018) Ryan H. Purcell et al.   Annual Review of Pharmacology and Toxicology

Gpr97 Exacerbates AKI by Mediating Sema3A Signaling

(2018) Wei Fang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Dynamics of Transcription Regulation in Human Bone Marrow Myeloid Differentiation to Mature Blood Neutrophils

(2018) Luigi Grassi et al.   Cell Reports

GPR56/ADGRG1 Activation Promotes Melanoma Cell Migration via NTF Dissociation and CTF-Mediated Gα 12/13 /RhoA Signaling

(2017) Nien-Yi Chiang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Selectivity determinants of GPCR–G-protein binding

(2017) Tilman Flock et al.   NATURE

Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

(2017) Nicole Scholz et al.   eLife

Comparative Analysis of the Host Response to Community-acquired and Hospital-acquired Pneumonia in Critically Ill Patients

(2016) Lonneke A. van Vught et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The constitutive activity of the adhesion GPCR GPR114/ADGRG5 is mediated by its tethered agonist

(2016) Caroline Wilde et al.   FASEB JOURNAL

Broad defects in the energy metabolism of leukocytes underlie immunoparalysis in sepsis

(2016) Shih-Chin Cheng et al.   NATURE IMMUNOLOGY

Transcriptome analysis of G protein-coupled receptors in distinct genetic subgroups of acute myeloid leukemia: identification of potential disease-specific targets

(2016) A Maiga et al.   Blood Cancer Journal

Increased EMR2 expression on neutrophils correlates with disease severity and predicts overall mortality in cirrhotic patients

(2016) Chien-Hao Huang et al.   Scientific Reports

Gpr97 is dispensable for metabolic syndrome but is involved in macrophage inflammation in high-fat diet-induced obesity in mice

(2016) Jueping Shi et al.   Scientific Reports

The Adhesion G Protein-Coupled Receptor GPR56/ADGRG1 Is an Inhibitory Receptor on Human NK Cells

(2016) Gin-Wen Chang et al.   Cell Reports

A Molecular Biomarker to Diagnose Community-acquired Pneumonia on Intensive Care Unit Admission

(2015) Brendon P. Scicluna et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Identification of the tethered peptide agonist of the adhesion G protein-coupled receptor GPR64/ADGRG2

(2015) Lilian M. Demberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RNA binding proteins as regulators of immune cell biology

(2015) R. Newman et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

The Selective Sirtuin 1 Activator SRT2104 Reduces Endotoxin-Induced Cytokine Release and Coagulation Activation in Humans*

(2015) Anne J. van der Meer et al.   CRITICAL CARE MEDICINE

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adhesion GPCR Latrophilin/CIRL Shapes Mechanosensation

(2015) Nicole Scholz et al.   Cell Reports

Gpr97 Is Dispensable for Inflammation in OVA-Induced Asthmatic Mice

(2015) Jue-ping Shi et al.   PLoS One

The eosinophil surface receptor epidermal growth factor–like module containing mucin-like hormone receptor 1 (EMR1): A novel therapeutic target for eosinophilic disorders

(2014) Fanny Legrand et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A network approach to clinical intervention in neurodegenerative diseases

(2014) Jose A. Santiago et al.   TRENDS IN MOLECULAR MEDICINE

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Neutrophil cell surface receptors and their intracellular signal transduction pathways

(2013) Krisztina Futosi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

The Orphan Adhesion G Protein-coupled Receptor GPR97 Regulates Migration of Lymphatic Endothelial Cells via the Small GTPases RhoA and Cdc42

(2013) Nadejda Valtcheva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Gpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decision

(2013) J-j Wang et al.   Cell Death & Disease

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

Signaling property study of adhesion G-protein-coupled receptors

(2012) Jamila Gupte et al.   FEBS LETTERS

F4/80 and the related adhesion-GPCRs

(2011) Siamon Gordon et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Specific expression of GPR56 by human cytotoxic lymphocytes

(2011) Yen-Ming Peng et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Clinical microfluidics for neutrophil genomics and proteomics

(2010) Kenneth T Kotz et al.   NATURE MEDICINE

Site-specific N-glycosylation regulates the GPS auto-proteolysis of CD97

(2009) Cheng-Chih Hsiao et al.   FEBS LETTERS

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function

(2007) Simon Yona et al.   FASEB JOURNAL