Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons

Adhesion G protein-coupled receptors in nervous system development and disease

(2016) Tobias Langenhan et al.   NATURE REVIEWS NEUROSCIENCE

Vibratory Urticaria Associated with a Missense Variant in ADGRE2

(2016) Steven E. Boyden et al.   NEW ENGLAND JOURNAL OF MEDICINE

cAMP Signals in Drosophila Motor Neurons Are Confined to Single Synaptic Boutons

(2016) Isabella Maiellaro et al.   Cell Reports

The Touching Tail of a Mechanotransduction Channel

(2015) Zachary A. Knecht et al.   CELL

Ankyrin Repeats Convey Force to Gate the NOMPC Mechanotransduction Channel

(2015) Wei Zhang et al.   CELL

AgingDrosophila melanogasterdisplay altered pre- and postsynaptic ultrastructure at adult neuromuscular junctions

(2015) Nicole Wagner et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Adhesion GPCR GPR126 Has Distinct, Domain-Dependent Functions in Schwann Cell Development Mediated by Interaction with Laminin-211

(2015) Sarah C. Petersen et al.   NEURON

Mechanically Activated Ion Channels

(2015) Sanjeev S. Ranade et al.   NEURON

Adhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonist

(2015) Hannah M. Stoveken et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adhesion GPCR Latrophilin/CIRL Shapes Mechanosensation

(2015) Nicole Scholz et al.   Cell Reports

Oriented Cell Division in the C. elegans Embryo Is Coordinated by G-Protein Signaling Dependent on the Adhesion GPCR LAT-1

(2015) Antje Müller et al.   PLoS Genetics

LPHN3, a presynaptic adhesion-GPCR implicated in ADHD, regulates the strength of neocortical layer 2/3 synaptic input to layer 5

(2014) Matthew L O’Sullivan et al.   Neural Development

G protein-coupled odorant receptors underlie mechanosensitivity in mammalian olfactory sensory neurons

(2014) Timothy Connelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

(2014) J. P. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Channelrhodopsin-2-XXL, a powerful optogenetic tool for low-light applications

(2014) A. Dawydow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative super-resolution imaging of Bruchpilot distinguishes active zone states

(2014) Nadine Ehmann et al.   Nature Communications

A Tethered Agonist within the Ectodomain Activates the Adhesion G Protein-Coupled Receptors GPR126 and GPR133

(2014) Ines Liebscher et al.   Cell Reports

Orphan G Protein–Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size

(2013) James P. Bridges et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Early Olfactory Processing in Drosophila: Mechanisms and Principles

(2013) Rachel I. Wilson   Annual Review of Neuroscience

Progress in demystification of adhesion G protein-coupled receptors

(2013) Ines Liebscher et al.   BIOLOGICAL CHEMISTRY

Sticky Signaling--Adhesion Class G Protein-Coupled Receptors Take the Stage

(2013) T. Langenhan et al.   Science Signaling

Matching structure with function: the GAIN domain of Adhesion-GPCR and PKD1-like proteins

(2013) Simone Prömel et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Hebbian Plasticity Guides Maturation of Glutamate Receptor Fields In Vivo

(2013) Dmitrij Ljaschenko et al.   Cell Reports

A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis

(2012) Demet Araç et al.   EMBO JOURNAL

High Affinity Neurexin Binding to Cell Adhesion G-protein-coupled Receptor CIRL1/Latrophilin-1 Produces an Intercellular Adhesion Complex

(2012) Antony A. Boucard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Drosophila NOMPC is a mechanotransduction channel subunit for gentle-touch sensation

(2012) Zhiqiang Yan et al.   NATURE

The GPS Motif Is a Molecular Switch for Bimodal Activities of Adhesion Class G Protein-Coupled Receptors

(2012) Simone Prömel et al.   Cell Reports

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

(2011) Sebastian Börner et al.   Nature Protocols

Latrophilin 1 and its endogenous ligand Lasso/teneurin-2 form a high-affinity transsynaptic receptor pair with signaling capabilities

(2011) J.-P. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AT1 receptors as mechanosensors

(2010) Michael Mederos y Schnitzler et al.   CURRENT OPINION IN PHARMACOLOGY

Light Modulation of Cellular cAMP by a Small Bacterial Photoactivated Adenylyl Cyclase, bPAC, of the Soil BacteriumBeggiatoa

(2010) Manuela Stierl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

The Role of the TRP Channel NompC in Drosophila Larval and Adult Locomotion

(2010) Li E. Cheng et al.   NEURON

Drosophila TRPN( = NOMPC) Channel Localizes to the Distal End of Mechanosensory Cilia

(2010) Jeongmi Lee et al.   PLoS One

Genomic mapping and expression patterns of C380, OK6 and D42 enhancer trap lines in the larval nervous system of Drosophila

(2009) Subhabrata Sanyal   GENE EXPRESSION PATTERNS

Directed, efficient, and versatile modifications of the Drosophila genome by genomic engineering

(2009) J. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction

(2008) Michael Mederos y Schnitzler et al.   EMBO JOURNAL

Efficient Ends-Out Gene Targeting In Drosophila

(2008) J. Huang et al.   GENETICS